The toxic nature of murine amylin and the immune responsivity of pancreatic islet to conformational antibody in mice

Prediabetes definitions and clinical outcomes

(2017) Luís Maurício T R Lima   Lancet Diabetes & Endocrinology

Analysis of the Amyloidogenic Potential of Pufferfish (Takifugu rubripes) Islet Amyloid Polypeptide Highlights the Limitations of Thioflavin-T Assays and the Difficulties in Defining Amyloidogenicity

(2016) Amy G. Wong et al.   BIOCHEMISTRY

Amyloidogenesis of the amylin analogue pramlintide

(2016) Dayana Cabral da Silva et al.   BIOPHYSICAL CHEMISTRY

Regulation of the assembly and amyloid aggregation of murine amylin by zinc

(2016) Luiza C.S. Erthal et al.   BIOPHYSICAL CHEMISTRY

The formation, function and regulation of amyloids: insights from structural biology

(2016) M. Landreh et al.   JOURNAL OF INTERNAL MEDICINE

A Comparison of Three Fluorophores for the Detection of Amyloid Fibers and Prefibrillar Oligomeric Assemblies. ThT (Thioflavin T); ANS (1-Anilinonaphthalene-8-sulfonic Acid); and bisANS (4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonic Acid)

(2015) Nadine D. Younan et al.   BIOCHEMISTRY

The pathogenic mechanism of diabetes varies with the degree of overexpression and oligomerization of human amylin in the pancreatic islet β cells

(2014) Shaoping Zhang et al.   FASEB JOURNAL

Stepwise oligomerization of murine amylin and assembly of amyloid fibrils

(2013) Leonardo C. Palmieri et al.   BIOPHYSICAL CHEMISTRY

 -Cell Failure in Type 2 Diabetes: A Case of Asking Too Much of Too Few?

(2013) S. Costes et al.   DIABETES

Fibril formation and toxicity of the non-amyloidogenic rat amylin peptide

(2012) Nathaniel G.N. Milton et al.   MICRON

Clustering and Internalization of Toxic Amylin Oligomers in Pancreatic Cells Require Plasma Membrane Cholesterol

(2011) Saurabh Trikha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?

(2010) S. Zraika et al.   DIABETOLOGIA

Islet architecture: A comparative study

(2010) Abraham Kim et al.   Islets

Evidence for Proteotoxicity in β Cells in Type 2 Diabetes

(2009) Tatyana Gurlo et al.   AMERICAN JOURNAL OF PATHOLOGY

Spontaneous Diabetes in Hemizygous Human Amylin Transgenic Mice That Developed Neither Islet Amyloid nor Peripheral Insulin Resistance

(2008) W. P.S. Wong et al.   DIABETES

Structural Classification of Toxic Amyloid Oligomers

(2008) Charles G. Glabe   JOURNAL OF BIOLOGICAL CHEMISTRY

Amyloid oligomers in diabetic and nondiabetic human pancreas

(2008) Hai-Lu Zhao et al.   Translational Research