Salvinorin A ameliorates cerebral vasospasm through activation of endothelial nitric oxide synthase in a rat model of subarachnoid hemorrhage

Intra-Arterial Nimodipine Infusion for Cerebral Vasospasm in Patients with Aneurysmal Subarachnoid Hemorrhage

(2017) W-S. Cho et al.   INTERVENTIONAL NEURORADIOLOGY

The role of rhynchophylline in alleviating early brain injury following subarachnoid hemorrhage in rats

(2016) Yan Zhang et al.   BRAIN RESEARCH

Highly selective non-opioid kappa opioid receptor (KOR) agonist salvinorin A protects against forebrain ischemia-induced brain injury in rats

(2016) Jihua Xin et al.   BRAIN RESEARCH

Knockout of programmed cell death 5 (PDCD5) gene attenuates neuron injury after middle cerebral artery occlusion in mice

(2016) Jianfei Lu et al.   BRAIN RESEARCH

Sulforaphane activates the cerebral vascular Nrf2–ARE pathway and suppresses inflammation to attenuate cerebral vasospasm in rat with subarachnoid hemorrhage

(2016) Xudong Zhao et al.   BRAIN RESEARCH

The Role of κ Opioid Receptor in Brain Ischemia

(2016) Chunhua Chen et al.   CRITICAL CARE MEDICINE

Phosphorylation of Akt by SC79 Prevents Iron Accumulation and Ameliorates Early Brain Injury in a Model of Experimental Subarachnoid Hemorrhage

(2016) Shuangying Hao et al.   MOLECULES

Alterations in the expression of protease-activated receptor 1 and tumor necrosis factor-α in the basilar artery of rats following a subarachnoid hemorrhage

(2016) GANG LI et al.   Experimental and Therapeutic Medicine

Role of Cyclooxygenase-2 in Relation to Nitric Oxide and Endothelin-1 on Pathogenesis of Cerebral Vasospasm After Subarachnoid Hemorrhage in Rabbit

(2016) Akira Munakata et al.   Translational Stroke Research

Hemoglobin induced NO/cGMP suppression Deteriorate Microcirculation via Pericyte Phenotype Transformation after Subarachnoid Hemorrhage in Rats

(2016) Qiang Li et al.   Scientific Reports

Recombinant osteopontin attenuates experimental cerebral vasospasm following subarachnoid hemorrhage in rats through an anti-apoptotic mechanism

(2015) Junchi He et al.   BRAIN RESEARCH

Memantine Attenuates Delayed Vasospasm after Experimental Subarachnoid Hemorrhage via Modulating Endothelial Nitric Oxide Synthase

(2015) Chih-Yuan Huang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Exendin-4-Loaded PLGA Microspheres Relieve Cerebral Ischemia/Reperfusion Injury and Neurologic Deficits through Long-Lasting Bioactivity-Mediated Phosphorylated Akt/eNOS Signaling in Rats

(2015) Chiang-Ting Chien et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cerebral vasospasm and corticospinal tract injury induced by a modified rat model of subarachnoid hemorrhage

(2015) Yang Qin et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Protective effects of thrombomodulin on microvascular permeability after subarachnoid hemorrhage in mouse model

(2015) T. Xu et al.   NEUROSCIENCE

Arctigenin, a Potent Ingredient ofArctium lappaL., Induces Endothelial Nitric Oxide Synthase and Attenuates Subarachnoid Hemorrhage-Induced Vasospasm through PI3K/Akt Pathway in a Rat Model

(2015) Chih-Zen Chang et al.   Biomed Research International

Pharmacology and anti-addiction effects of the novel κ opioid receptor agonist Mesyl Sal B, a potent and long-acting analogue of salvinorin A

(2014) B Simonson et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cannabinoid type 2 receptor stimulation attenuates brain edema by reducing cerebral leukocyte infiltration following subarachnoid hemorrhage in rats

(2014) Mutsumi Fujii et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Rat Endovascular Perforation Model

(2014) Fatima A. Sehba   Translational Stroke Research

Targeted over-expression of endothelin-1 in astrocytes leads to more severe brain damage and vasospasm after subarachnoid hemorrhage

(2013) Patrick KK Yeung et al.   BMC NEUROSCIENCE

Protective Effects of Urinary Trypsin Inhibitor on Vascular Permeability Following Subarachnoid Hemorrhage in a Rat Model

(2013) Ning Zhou et al.   CNS Neuroscience & Therapeutics

Delayed neurological deterioration after subarachnoid haemorrhage

(2013) R. Loch Macdonald   Nature Reviews Neurology

Potential Contribution of Hypoxia-Inducible Factor-1α, Aquaporin-4, and Matrix Metalloproteinase-9 to Blood–Brain Barrier Disruption and Brain Edema After Experimental Subarachnoid Hemorrhage

(2012) Zhong Wang et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Salvinorin A Administration after Global Cerebral Hypoxia/Ischemia Preserves Cerebrovascular Autoregulation via Kappa Opioid Receptor in Piglets

(2012) Zhenhong Wang et al.   PLoS One

Salvinorin A Pretreatment Preserves Cerebrovascular Autoregulation After Brain Hypoxic/Ischemic Injury via Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase in Piglets

(2011) Diansan Su et al.   ANESTHESIA AND ANALGESIA

Salvinorin A Produces Cerebrovasodilation through Activation of Nitric Oxide Synthase, κ Receptor, and Adenosine Triphosphate–sensitive Potassium Channel

(2011) Diansan Su et al.   ANESTHESIOLOGY

Improvement in neurological outcome and abolition of cerebrovascular endothelin B and 5-hydroxytryptamine 1B receptor upregulation through mitogen-activated protein kinase kinase 1/2 inhibition after subarachnoid hemorrhage in rats

(2010) Carl Christian Larsen et al.   JOURNAL OF NEUROSURGERY

Evaluation of the transport, in vitro metabolism and pharmacokinetics of Salvinorin A, a potent hallucinogen

(2009) Zeynep S. Teksin et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS