Copper-related toxicity in replicating and dormant Mycobacterium tuberculosis caused by 1-hydroxy-5-R-pyridine-2(1H)-thiones

New 1-hydroxy-2-thiopyridine derivatives active against both replicating and dormant Mycobacterium tuberculosis

(2017) Elena G. Salina et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Pharmacokinetic studies of a three-component complex that repurposes the front line antibiotic isoniazid against Mycobacterium tuberculosis

(2017) Thomas J. Manning et al.   TUBERCULOSIS

8-Hydroxyquinolines Are Boosting Agents of Copper-Related Toxicity in Mycobacterium tuberculosis

(2016) Santosh Shah et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Combinatorial phenotypic screen uncovers unrecognized family of extended thiourea inhibitors with copper-dependent anti-staphylococcal activity

(2016) Alex G. Dalecki et al.   Metallomics

Copper(II)-Bis(Thiosemicarbazonato) Complexes as Antibacterial Agents: Insights into Their Mode of Action and Potential as Therapeutics

(2015) Karrera Y. Djoko et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Disulfiram and Copper Ions Kill Mycobacterium tuberculosis in a Synergistic Manner

(2015) Alex G. Dalecki et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mycobacteria, metals, and the macrophage

(2015) Olivier Neyrolles et al.   IMMUNOLOGICAL REVIEWS

Copper homeostasis in Mycobacterium tuberculosis

(2015) Xiaoshan Shi et al.   Metallomics

Copper intoxication inhibits aerobic nucleotide synthesis in Streptococcus pneumoniae

(2015) Michael D. L. Johnson et al.   Metallomics

Copper tolerance and virulence in bacteria

(2015) Erik Ladomersky et al.   Metallomics

Facing multi-drug resistant tuberculosis

(2015) Giovanni Sotgiu et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Perturbation of copper homeostasis is instrumental in early developmental arrest of intraerythrocytic Plasmodium falciparum

(2014) Hiroko Asahi et al.   BMC MICROBIOLOGY

Novel drugs against tuberculosis: a clinician's perspective

(2014) Ioana Diana Olaru et al.   EUROPEAN RESPIRATORY JOURNAL

Antimicrobial effects of copper(ii) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action

(2014) Karrera Y. Djoko et al.   Metallomics

Co(II) and Cu(II) pyrophosphate complexes have selectivity and potency against Mycobacteria including Mycobacterium tuberculosis

(2013) Amanda E. Hoffman et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

A Multicopper Oxidase Is Required for Copper Resistance in Mycobacterium tuberculosis

(2013) J. L. Rowland et al.   JOURNAL OF BACTERIOLOGY

PATRIC, the bacterial bioinformatics database and analysis resource

(2013) Alice R. Wattam et al.   NUCLEIC ACIDS RESEARCH

Copper-Boosting Compounds: a Novel Concept for Antimycobacterial Drug Discovery

(2012) A. Speer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Delamanid for Multidrug-Resistant Pulmonary Tuberculosis

(2012) Maria Tarcela Gler et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resistance mechanisms of Mycobacterium tuberculosis against phagosomal copper overload

(2012) Jennifer L. Rowland et al.   TUBERCULOSIS

Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data

(2011) T. Carver et al.   BIOINFORMATICS

Copper toxicity and the origin of bacterial resistance—new insights and applications

(2011) Christopher L. Dupont et al.   Metallomics

Copper resistance is essential for virulence of Mycobacterium tuberculosis

(2011) F. Wolschendorf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dormant ovoid cells of Mycobacterium tuberculosis are formed in response to gradual external acidification

(2011) Margarita O. Shleeva et al.   TUBERCULOSIS

Copper Stress Affects Iron Homeostasis by Destabilizing Iron-Sulfur Cluster Formation in Bacillus subtilis

(2010) S. Chillappagari et al.   JOURNAL OF BACTERIOLOGY

A novel copper-responsive regulon in Mycobacterium tuberculosis

(2010) Richard A. Festa et al.   MOLECULAR MICROBIOLOGY

TubercuList – 10 years after

(2010) Jocelyne M. Lew et al.   TUBERCULOSIS

Gene ontology analysis for RNA-seq: accounting for selection bias

(2010) Matthew D Young et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity

(2009) L. Macomber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis

(2009) V. Makarov et al.   SCIENCE

The Global Responses of Mycobacterium tuberculosis to Physiological Levels of Copper

(2008) S. K. Ward et al.   JOURNAL OF BACTERIOLOGY

Identification of a copper-binding metallothionein in pathogenic mycobacteria

(2008) Ben Gold et al.   Nature Chemical Biology