Article
Medicine, General & Internal
Ruzica Jurcevic, Lazar Angelkov, Nebojsa Tasic, Milosav Tomovic, Dejan Kojic, Petar Otasevic, Milovan Bojic
Summary: This study introduces PVIOD as a new semiquantitative measure for AF catheter ablation efficacy, and identifies longstanding persistent AF, left atrial diameter, and left ventricular ejection fraction as independent predictors associated with PVIOD.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Julian Mueller, Karin Nentwich, Artur Berkovitz, Kai Sonne, Olena Kozlova, Sebastian Barth, Alexandru Deacanu, Christian Waechter, Philipp Halbfass, Heiko Lehrmann, Thomas Deneke
Summary: This study investigated the characteristics of patients undergoing redo AF ablation and the impact of different ablation strategies. The results showed that pulmonary vein reconnection was common among all techniques of AF ablation, and different ablation strategies did not improve long-term success.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Iva Krizanovic-Grgic, Shehab Anwer, Jan Steffel, Daniel Hofer, Ardan M. Saguner, Christina M. Spengler, Alexander Breitenstein, Felix C. Tanner
Summary: This study investigated the association of 2D and 3D left atrial strain with low-voltage area in relation to the recurrence of atrial fibrillation after pulmonary vein isolation. The results showed that 3D left atrial reservoir strain and pump strain were lower in patients with recurrent AF. Furthermore, the association of 3D left atrial strain with recurrence of AF was independent of other clinical and echocardiographic parameters, making it a potential predictor for outcomes in patients undergoing PVI.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Chi Cai, Jing Wang, Hong-Xia Niu, Jian-Min Chu, Wei Hua, Shu Zhang, Yan Yao
Summary: This study investigates the association between lesion size index (LSI) and acute conduction gap formation during high-power (HP) ablation for pulmonary vein isolation (PVI) in atrial fibrillation (AF) patients. Using LSI-guided HP ablation, a LSI value above 4.35 for all PV segments showed the best predictive value in avoiding gap formation for effective first-pass PVI. The optimal LSI cutoff values for predicting gap formation were 4.55 for the anterior wall and 3.95 for the posterior wall.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Leon Zwimpfer, Stefanie Aeschbacher, Philipp Krisai, Michael Coslovsky, Anne Springer, Rebecca E. Paladini, Marc Girod, Janik Hufschmid, Sven Knecht, Patrick Badertscher, Jurg H. Beer, Leo H. Bonati, Christine S. Zuern, Laurent Roten, Tobias Reichlin, Christian Sticherling, David Conen, Stefan Osswald, Michael Kuhne
Summary: In the Swiss Atrial Fibrillation Cohort study, there was no consistent evidence of an association between pulmonary vein isolation (PVI) and neurocognitive function in atrial fibrillation patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Andreas A. Boehmer, Moritz Rothe, Celine Zezyk, Christina M. Soether, Bianca C. Dobre, Bernhard M. Kaess, Joachim R. Ehrlich
Summary: This study aimed to evaluate the impact of age on the efficacy and safety of cryoballoon pulmonary vein isolation (cryoPVI) in elderly patients. The results showed that elderly patients (>=75 years) had an approximately threefold higher risk of symptomatic atrial fibrillation (AF) recurrence after cryoPVI compared to younger patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Yun Young Choi, Jaemin Shim, Yun Gi Kim, Kyongjin Min, Seung-Young Roh, Jin Seok Kim, Jong-Il Choi, Young-Hoon Kim
Summary: Adenosine-induced atrial fibrillation (AIAF) does not affect the long-term recurrence rate after pulmonary vein isolation (PVI). Additional ablation for the trigger site of AIAF does not improve clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Peter M. Kistler, David Chieng, Hariharan Sugumar, Liang-Han Ling, Louise Segan, Sonia Azzopardi, Ahmed Al-Kaisey, Ramanathan Parameswaran, Robert D. Anderson, Joshua Hawson, Sandeep Prabhu, Aleksandr Voskoboinik, Geoffrey Wong, Joseph B. Morton, Bhupesh Pathik, Alex J. McLellan, Geoffrey Lee, Michael Wong, Sue Finch, Rajeev K. Pathak, Deep Chandh Raja, Laurence Sterns, Matthew Ginks, Christopher M. Reid, Prashanthan Sanders, Jonathan M. Kalman
Summary: This randomized clinical trial compares pulmonary vein isolation (PVI) vs PVI with posterior wall isolation for achieving freedom from atrial arrhythmia in adult patients with persistent atrial fibrillation undergoing first-time catheter ablation in Australia, the UK, and Canada. The study findings suggest that adding posterior wall isolation to PVI does not significantly improve freedom from atrial arrhythmias in patients with persistent AF. Therefore, the empirical inclusion of posterior wall isolation for ablation of persistent AF may not be supported.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2023)
Article
Medicine, General & Internal
Philippe Taghji, Jean-Claude Deharo, Sana Amraoui, Sok-Sithikun Bun
Summary: This study evaluated the efficacy of CLOSE-guided pulmonary vein isolation (PVI) in the treatment of persistent atrial fibrillation (AF). The results showed that CLOSE-guided PVI achieved a high single-procedure arrhythmia-free survival rate of 80% at 1 year under intensive cardiac rhythm monitoring. However, larger-scale studies are still needed to further confirm these findings.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Nandor Szegedi, Judit Simon, Balint Szilveszter, Zoltan Sallo, Szilvia Herczeg, Lili Szaraz, Marton Kolossvary, Gabor Orban, Gabor Szeplaki, Klaudia Vivien Nagy, Mohammed El Mahdiui, Jeff M. Smit, Victoria Delgado, Jeroen J. Bax, Pal Maurovich-Horvat, Bela Merkely, Laszlo Geller
Summary: This study evaluated the impact of the spatial relationship between LSPV and LAA on recurrence after catheter ablation for paroxysmal AF. The study found that an abutting LAA-LSPV was associated with a higher chance of AF recurrence.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Michelle Lycke, Maria Kyriakopoulou, Milad El Haddad, Jean-Yves Wielandts, Gabriela Hilfiker, Alexandre Almorad, Teresa Strisciuglio, Jan De Pooter, Michael Wolf, Philippe Unger, Yves Vandekerckhove, Rene Tavernier, Jean-Benoit e Polain de Waroux, Mattias Duytschaever, Sebastien Knecht
Summary: The study aimed to identify predictors for atrial fibrillation (AF) recurrence 1 year after CLOSE-guided pulmonary vein isolation (PVI) in patients with paroxysmal AF.
Article
Cardiac & Cardiovascular Systems
Daehoon Kim, Taehyun Hwang, Min Kim, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
Summary: Extra-pulmonary vein triggers are commonly found in atrial fibrillation patients and associated with poorer rhythm outcomes after both de novo and repeat catheter ablation procedures.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Giulio Falasconi, Diego Penela, David Soto-Iglesias, Pietro Francia, Cheryl Teres, Andrea Saglietto, Beatriz Jauregui, Daniel Viveros, Aldo Bellido, Jose Alderete, Julia Meca-Santamaria, Paula Franco, Carlo Gaspardone, Rodolfo San Antonio, Marina Huguet, Oscar Camara, Jose-Tomas Ortiz-Perez, Julio Marti-Almor, Antonio Berruezo
Summary: The study aimed to personalize the ablation index (AI) based on left atrial wall thickness (LAWT) and investigate its effectiveness in PV antrum isolation for persistent atrial fibrillation (PeAF). The results showed that this personalized approach was effective and efficient, with low procedure, fluoroscopy, and RF time. The importance of this study lies in providing a new method for the treatment of PeAF.
Article
Cardiac & Cardiovascular Systems
Arash Aryana, Anna M. Thiemann, Deep K. Pujara, Laura L. Cossette, Shelley L. Allen, Mark R. Bowers, Maheer Gandhavadi, Russell Heath, Amar D. Trivedi, Padraig Gearoid O'Neill, Ethan R. Ellis, Andre d'Avila
Summary: This study investigated the acute and long-term outcomes of cryoballoon PVI vs PVI+PWI in patients with symptomatic PAF. The results showed that PVI+PWI treatment was associated with greater freedom from recurrent atrial arrhythmias and AF during long-term follow-up, compared to PVI alone.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2023)
Article
Medicine, General & Internal
Sebastian Weyand, Viola Adam, Matthias Beuter, Simon Hanger, David Heinzmann, Willibald Schrezenmeier, Peter Seizer
Summary: For patients undergoing radiofrequency pulmonary vein isolation, the necessity of pulmonary vein angiography was investigated after the use of high-resolution mapping catheters and high-power, short-duration ablation technique. The study found that omitting pulmonary vein angiography had no significant impact on the efficacy, efficiency, and complications of the ablation procedure. Therefore, avoiding pulmonary vein angiography may be useful, especially for young patients and those with chronic renal disease, when using this protocol.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Cory M. Tschabrunn, Sara Attalla, Jonathan Salas, David S. Frankel, Matthew C. Hyman, Emily Simon, Tiffany Sharkoski, David J. Callans, Gregory E. Supple, Saman Nazarian, David Lin, Robert D. Schaller, Sanjay Dixit, Francis E. Marchlinski, Pasquale Santangeli
Summary: Active esophageal cooling using the Attune Medical Esophageal Heat Transfer Device may reduce the occurrence of severe endoscopically detected esophageal thermal lesions, offering potential benefits in preventing complications following radiofrequency catheter ablation for atrial fibrillation.
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Brianna F. Moon, Srikant Kamesh Iyer, Nicholas J. Josselyn, Eileen Hwuang, Sophia Swago, Samuel J. Keeney, Estibaliz Castillero, Giovanni Ferrari, James J. Pilla, Joseph H. Gorman, Robert C. Gorman, Cory M. Tschabrunn, Haochang Shou, William Matthai, Felix W. Wehrli, Victor A. Ferrari, Yuchi Han, Harold Litt, Walter R. Witschey
Summary: The study compared Delta chi and R2* in subacute myocardial infarction at 3T and 7T, finding that magnetic susceptibility did not significantly differ across field strengths, while R2* showed a significant difference. The study concluded that R2* was dependent on field strength, while Delta chi showed independence, with histology validating the presence of iron and supporting imaging findings.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Martin R. Arceluz, Ioan Liuba, Cory M. Tschabrunn, David S. Frankel, Pasquale Santangeli, Gregory E. Supple, Robert D. Schaller, Fermin C. Garcia, David J. Callans, Gustavo S. Guandalini, Katie Walsh, Saman Nazarian, Erica S. Zado, Francis E. Marchlinski
Summary: In left ventricular nonischemic cardiomyopathy, the presence and location of ventricular tachycardia substrate can be identified by reduced QRS amplitude and QRS fractionation during sinus rhythm. Low frontal plane QRS amplitude and multilead QRS fractionation are associated with ventricular tachycardia substrate, but can also be present in patients without ventricular tachycardia.
Article
Cardiac & Cardiovascular Systems
Cory M. Tschabrunn, Erica S. Zado, Robert D. Schaller, Fermin C. Garcia, Ramanan Kumareswaran, Weihow Hsue, Pasquale Santangeli, Francis E. Marchlinski
Summary: In patients with arrhythmogenic right ventricular cardiomyopathy (ARVC) and ventricular tachycardia (VT), isolated epicardial substrate (IES) abnormalities can be present. Ablation of the epicardium can eliminate VT and result in long-term VT-free survival.
Editorial Material
Cardiac & Cardiovascular Systems
Cory M. Tschabrunn, Pasquale Santangeli
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Katie A. Walsh, Jonathan M. Daw, Aung Lin, Gustavo Guandalini, Matthew C. Hyman, Ramanan Kumareswaran, Jeffrey S. Arkles, Robert D. Schaller, Gregory E. Supple, David S. Frankel, Saman Nazarian, Michael P. Riley, Fermin Garcia, David Lin, Cory Tschabrunn, Sanjay Dixit, Andrew E. Epstein, David J. Callans, Francis E. Marchlinski, Pasquale Santangeli
Summary: Right ventricular (RV) involvement in postinfarction ventricular tachycardia (VT) is rare, but critical RV substrate (CRVS) was identified in 2.1% of cases. RV mapping should be considered in cases where left ventricular (LV) mapping fails to demonstrate adequate targets, especially in patients with left bundle branch block (LBBB) morphology VT. After RV ablation, 80% of patients had no VT recurrence, but 41% died during follow-up.
Article
Veterinary Sciences
Alexandra Crooks, Weihow Hsue, Cory M. Tschabrunn, Anna R. Gelzer
Summary: This study describes the use of electroanatomic mapping and radiofrequency catheter ablation (RFCA) to guide treatment for ventricular tachycardia (VT) in Boxers. The results show that RFCA can decrease the number of VT episodes and improve clinical signs in Boxers. However, there are potential complications associated with the procedure. Further research is needed to understand the anatomical substrate and electrophysiological mechanisms of VT.
JOURNAL OF VETERINARY INTERNAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Bahman Hooshdaran, Benjamin B. Pressly, Ivan S. Alferiev, Jonathan D. Smith, Philip W. Zoltick, Cory M. Tschabrunn, Robert L. Wilensky, Robert C. Gorman, Robert J. Levy, Ilia Fishbein
Summary: This study investigated whether local delivery of adeno-associated viral (AAV) vectors expressing oxidation-resistant apoA1(4WF) preserves apoA1 functionality. The results showed that apoA1(4WF) improved cholesterol efflux and inhibited cell proliferation, but failed to prevent in-stent restenosis in the presence of severe atherosclerotic disease.
SCIENTIFIC REPORTS
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Cory M. Tschabrunn, David S. Frankel
JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Cory M. Tschabrunn, Pasquale Santangeli
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2022)
Article
Veterinary Sciences
W. Hsue, A. R. Gelzer, C. M. Tschabrunn
Summary: This article reports on the successful treatment of a five-year-old dog with paroxysmal supraventricular tachycardia using three-dimensional electroanatomical mapping and radiofrequency ablation. The dog recovered without complications and had no recurrence of tachycardia.
JOURNAL OF VETERINARY CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Jonathan M. Daw, C. Anwar A. Chahal, Jeffrey S. Arkles, David J. Callans, Sanjay Dixit, Andrew E. Epstein, David S. Frankel, Fermin C. Garcia, Matthew C. Hyman, Ramanan Kumareswaran, David Lin, Saman Nazarian, Michael P. Riley, Pasquale Santangeli, Robert D. Schaller, Gregory E. Supple, Cory Tschabrunn, Francis E. Marchlinski, Rajat Deo
Summary: The Brugada pattern in patients with Brugada syndrome is often dynamic, and most patients have a low risk of lethal arrhythmic events.
Meeting Abstract
Cardiac & Cardiovascular Systems
Munveer Thind, Martin Arceluz, Qing Lou, Sara Ciaverelli, Irene Lucena Padros, Maciej Kubala, Bishnu P. Dhakal, Weeranun D. Bode, Maxime Cerantola, Maiwand Mirwais, Kelvin Bush, Erica S. Zado, Gustavo Guandalini, Matthew C. Hyman, David Lin, Rajat Deo, Saman Nazarian, Cory M. Tschabrunn, Robert D. Schaller, Andrew E. Epstein, Gregory E. Supple, David S. Frankel
Meeting Abstract
Cardiac & Cardiovascular Systems
Munveer Thind, Martin Arceluz, Irene Lucena Padros, Maciej Kubala, Bishnu P. Dhakal, Weeranun D. Bode, Maxime Cerantola, Maiwand Mirwais, Kelvin Bush, Gustavo Guandalini, Matthew C. Hyman, David Lin, Rajat Deo, Saman Nazarian, Cory M. Tschabrunn, Robert D. Schaller, Andrew E. Epstein, Gregory E. Supple, David S. Frankel, Pasquale Santangeli
Correction
Cardiac & Cardiovascular Systems
C. M. Tschabrunn, Naga Venkata K. Pothineni, William H. Sauer, Daniel Doynow, Jonathan Salas, Ting-Wei Liao, Pasquale Santangeli, Jeffrey Arkles, Matthew C. Hyman, David S. Frankel, Gregory E. Supple, Fermin C. Garcia, Saman Nazarian, Sanjay Dixit, Andrew E. Epstein, Robert D. Schaller, David J. Callans, Francis E. Marchlinski
JACC-CLINICAL ELECTROPHYSIOLOGY
(2022)