Haliotis discus discus Sialic Acid-Binding Lectin Reduces the Oncolytic Vaccinia Virus Induced Toxicity in a Glioblastoma Mouse Model

A hypoxia- and telomerase-responsive oncolytic adenovirus expressing secretable trimeric TRAIL triggers tumour-specific apoptosis and promotes viral dispersion in TRAIL-resistant glioblastoma

(2018) Eonju Oh et al.   Scientific Reports

Ulva pertusa lectin 1 delivery through adenovirus vector affects multiple signaling pathways in cancer cells

(2017) Gongchu Li et al.   GLYCOCONJUGATE JOURNAL

Oncolytic virus therapy: A new era of cancer treatment at dawn

(2016) Hiroshi Fukuhara et al.   CANCER SCIENCE

The challenges associated with molecular targeted therapies for glioblastoma

(2016) Toni Rose Jue et al.   JOURNAL OF NEURO-ONCOLOGY

cDNA and Gene Structure of MytiLec-1, A Bacteriostatic R-Type Lectin from the Mediterranean Mussel (Mytilus galloprovincialis)

(2016) Imtiaj Hasan et al.   Marine Drugs

Crystal structure of MytiLec, a galactose-binding lectin from the mussel Mytilus galloprovincialis with cytotoxicity against certain cancer cell types

(2016) Daiki Terada et al.   Scientific Reports

Effective treatment of glioblastoma requires crossing the blood–brain barrier and targeting tumors including cancer stem cells: The promise of nanomedicine

(2015) Sang-Soo Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Galectin expression in cancer diagnosis and prognosis: A systematic review

(2015) Victor L. Thijssen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

The Impact of Macrophage- and Microglia-Secreted TNF  on Oncolytic HSV-1 Therapy in the Glioblastoma Tumor Microenvironment

(2015) W. H. Meisen et al.   CLINICAL CANCER RESEARCH

Overcoming the blood–brain tumor barrier for effective glioblastoma treatment

(2015) O. van Tellingen et al.   DRUG RESISTANCE UPDATES

Microglia and astrocytes attenuate the replication of the oncolytic vaccinia virus LIVP 1.1.1 in murine GL261 gliomas by acting as vaccinia virus traps

(2015) Christina Kober et al.   Journal of Translational Medicine

MytiLec, a Mussel R-Type Lectin, Interacts with Surface Glycan Gb3 on Burkitt’s Lymphoma Cells to Trigger Apoptosis through Multiple Pathways

(2015) Imtiaj Hasan et al.   Marine Drugs

Anti-cancer effects of enteric-coated polymers containing mistletoe lectin in murine melanoma cells in vitro and in vivo

(2015) Seung-Yeon Han et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Lectins with Potential for Anti-Cancer Therapy

(2015) Tammy Yau et al.   MOLECULES

Potentiating oncolytic viral therapy through an understanding of the initial immune responses to oncolytic viral infection

(2015) Christopher A Alvarez-Breckenridge et al.   Current Opinion in Virology

Cellular Factors Promoting Resistance to Effective Treatment of Glioma with Oncolytic Myxoma Virus

(2014) F. J. Zemp et al.   CANCER RESEARCH

Plant lectins, from ancient sugar-binding proteins to emerging anti-cancer drugs in apoptosis and autophagy

(2014) Q.-L. Jiang et al.   CELL PROLIFERATION

Integrin antagonist augments the therapeutic effect of adenovirus-mediated REIC/Dkk-3 gene therapy for malignant glioma

(2014) Y Shimazu et al.   GENE THERAPY

Stem Cells Loaded With Multimechanistic Oncolytic Herpes Simplex Virus Variants for Brain Tumor Therapy

(2014) Matthias Duebgen et al.   JNCI-Journal of the National Cancer Institute

Adenovirus Carrying Gene Encoding Haliotis discus discus Sialic Acid Binding Lectin Induces Cancer Cell Apoptosis

(2014) Xinyan Yang et al.   Marine Drugs

CD123 targeting oncolytic adenoviruses suppress acute myeloid leukemia cell proliferation in vitro and in vivo

(2014) G Li et al.   Blood Cancer Journal

Exogenous expression of marine lectins DlFBL and SpRBL induces cancer cell apoptosis possibly through PRMT5-E2F-1 pathway

(2014) Liqin Wu et al.   Scientific Reports

Interferon Induced IFIT Family Genes in Host Antiviral Defense

(2013) Xiang Zhou et al.   International Journal of Biological Sciences

Oncolytic viruses as therapeutic cancer vaccines

(2013) David L Bartlett et al.   Molecular Cancer

Preferential Replication of Systemically Delivered Oncolytic Vaccinia Virus in Focally Irradiated Glioma Xenografts

(2012) S. J. Advani et al.   CLINICAL CANCER RESEARCH

Oncolytic measles virus strains have significant antitumor activity against glioma stem cells

(2012) C Allen et al.   GENE THERAPY

A Lectin from the MusselMytilus galloprovincialisHas a Highly Novel Primary Structure and Induces Glycan-mediated Cytotoxicity of Globotriaosylceramide-expressing Lymphoma Cells

(2012) Yuki Fujii et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oncolytic virotherapy

(2012) Stephen J Russell et al.   NATURE BIOTECHNOLOGY

Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end?

(2012) Shota Tanaka et al.   Nature Reviews Clinical Oncology

Current status of gene therapy for brain tumors

(2012) Andrea M. Murphy et al.   Translational Research

A Mechanistic Proof-of-concept Clinical Trial With JX-594, a Targeted Multi-mechanistic Oncolytic Poxvirus, in Patients With Metastatic Melanoma

(2011) Tae-Ho Hwang et al.   MOLECULAR THERAPY

The Oncolytic Poxvirus JX-594 Selectively Replicates in and Destroys Cancer Cells Driven by Genetic Pathways Commonly Activated in Cancers

(2011) Kelley A Parato et al.   MOLECULAR THERAPY

Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans

(2011) Caroline J. Breitbach et al.   NATURE

Toxicity and Activity of a Twice Daily High-dose Bolus Interleukin 2 Regimen in Patients With Metastatic Melanoma and Metastatic Renal Cell Cancer

(2009) Nicolas Acquavella et al.   JOURNAL OF IMMUNOTHERAPY