Enterobacteria and host resistance to infection

Development and application of CRISPR/Cas9 technologies in genomic editing

(2018) Cui Zhang et al.   HUMAN MOLECULAR GENETICS

Loss of disease tolerance during Citrobacter rodentium infection is associated with impaired epithelial differentiation and hyperactivation of T cell responses

(2018) Eugene Kang et al.   Scientific Reports

Enhanced Macrophage M1 Polarization and Resistance to Apoptosis Enable Resistance to Plague

(2017) Emilia Pachulec et al.   JOURNAL OF INFECTIOUS DISEASES

The infectious hypoxia: occurrence and causes during Shigella infection

(2017) Ellen T. Arena et al.   MICROBES AND INFECTION

Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis

(2017) Michael Sigal et al.   NATURE

Antibiofilm activities of norharmane and its derivatives against Escherichia coli O157:H7 and other bacteria

(2017) Jin-Hyung Lee et al.   PHYTOMEDICINE

Identification of novel substrates of Shigella T3SA through analysis of its virulence plasmid-encoded secretome

(2017) Laurie Pinaud et al.   PLoS One

Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility

(2017) Anthony S. Piro et al.   mBio

Citrobacter rodentium Relies on Commensals for Colonization of the Colonic Mucosa

(2017) Caroline Mullineaux-Sanders et al.   Cell Reports

Optimizing Genomic Methods for Mapping and Identification of Candidate Variants in ENU Mutagenesis Screens Using Inbred Mice

(2017) Krista A. Geister et al.   G3-Genes Genomes Genetics

How Do the Virulence Factors of Shigella Work Together to Cause Disease?

(2017) Emily Mattock et al.   Frontiers in Cellular and Infection Microbiology

Resistance of Mice of the 129 Background to Yersinia pestis Maps to Multiple Loci on Chromosome 1

(2016) Michael Tencati et al.   INFECTION AND IMMUNITY

Deletion of toxin–antitoxin systems in the evolution of Shigella sonnei as a host-adapted pathogen

(2016) Gareth McVicker et al.   Nature Microbiology

Essential Oils and Eugenols Inhibit Biofilm Formation and the Virulence of Escherichia coli O157:H7

(2016) Yong-Guy Kim et al.   Scientific Reports

Mapping of genetic loci that modulate differential colonization by Escherichia coli O157:H7 TUV86-2 in advanced recombinant inbred BXD mice

(2015) Lisa M. Russo et al.   BMC GENOMICS

Reported Foodborne Outbreaks Due to Fresh Produce in the United States and European Union: Trends and Causes

(2015) Raquel M. Callejón et al.   Foodborne Pathogens and Disease

Comparison of Models for Bubonic Plague Reveals Unique Pathogen Adaptations to the Dermis

(2015) Rodrigo J. Gonzalez et al.   INFECTION AND IMMUNITY

Citrobacter rodentium -induced colitis: A robust model to study mucosal immune responses in the gut

(2015) Ekaterina P. Koroleva et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Genetic variants associated with non-typhoidal Salmonella bacteraemia in African children

(2015) James J Gilchrist et al.   LANCET

Now you see me, now you don't: the interaction of Salmonella with innate immune receptors

(2015) A. Marijke Keestra-Gounder et al.   NATURE REVIEWS MICROBIOLOGY

Bioimage analysis ofShigellainfection reveals targeting of colonic crypts

(2015) Ellen T. Arena et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatially Distinct Neutrophil Responses within the Inflammatory Lesions of Pneumonic Plague

(2015) Nikolas M. Stasulli et al.   mBio

World Health Organization Global Estimates and Regional Comparisons of the Burden of Foodborne Disease in 2010

(2015) Arie H. Havelaar et al.   PLOS MEDICINE

The Rising Dominance of Shigella sonnei: An Intercontinental Shift in the Etiology of Bacillary Dysentery

(2015) Corinne N. Thompson et al.   PLoS Neglected Tropical Diseases

Shigella Manipulates Host Immune Responses by Delivering Effector Proteins with Specific Roles

(2015) Hiroshi Ashida et al.   Frontiers in Immunology

Salmonella entericaSerovar Typhi and the Pathogenesis of Typhoid Fever

(2014) Gordon Dougan et al.   Annual Review of Microbiology

A Fluorescent Reporter Reveals On/Off Regulation of the Shigella Type III Secretion Apparatus during Entry and Cell-to-Cell Spread

(2014) François-Xavier Campbell-Valois et al.   Cell Host & Microbe

Contribution of increased ISG15, ISGylation and deregulated type I IFN signaling in Usp18 mutant mice during the course of bacterial infections

(2014) S M Dauphinee et al.   GENES AND IMMUNITY

The association between malaria and non-typhoid Salmonella bacteraemia in children in sub-Saharan Africa: a literature review

(2014) Ebako Takem et al.   MALARIA JOURNAL

Variation at HLA-DRB1 is associated with resistance to enteric fever

(2014) Sarah J Dunstan et al.   NATURE GENETICS

Citrobacter rodentium: infection, inflammation and the microbiota

(2014) James W. Collins et al.   NATURE REVIEWS MICROBIOLOGY

New Insights into How Yersinia pestis Adapts to Its Mammalian Host during Bubonic Plague

(2014) Elizabeth Pradel et al.   PLoS Pathogens

Mouse ENU Mutagenesis to Understand Immunity to Infection: Methods, Selected Examples, and Perspectives

(2014) Grégory Caignard et al.   Genes

Recent Advances in Understanding Enteric Pathogenic Escherichia coli

(2013) M. A. Croxen et al.   CLINICAL MICROBIOLOGY REVIEWS

A Shigella Effector Dampens Inflammation by Regulating Epithelial Release of Danger Signal ATP through Production of the Lipid Mediator PtdIns5P

(2013) Andrea Puhar et al.   IMMUNITY

Altered IFN- -Mediated Immunity and Transcriptional Expression Patterns in N-Ethyl-N-Nitrosourea-Induced STAT4 Mutants Confer Susceptibility to Acute Typhoid-like Disease

(2013) M. M. Eva et al.   JOURNAL OF IMMUNOLOGY

A Mouse Model of Shigellosis by Intraperitoneal Infection

(2013) Jin-Young Yang et al.   JOURNAL OF INFECTIOUS DISEASES

Suppression of Hepcidin Expression and Iron Overload Mediate Salmonella Susceptibility in Ankyrin 1 ENU-Induced Mutant

(2013) Kyoko E. Yuki et al.   PLoS One

R-Spondin 2 signalling mediates susceptibility to fatal infectious diarrhoea

(2013) Olivier Papapietro et al.   Nature Communications

EnterohaemorrhagicEscherichia coli O157:H7 Shiga-like toxin 1 is required for full pathogenicity and activation of the p38 mitogen-activated protein kinase pathway inCaenorhabditis elegans

(2012) T-C. Chou et al.   CELLULAR MICROBIOLOGY

Resistance to plague of Mus spretus SEG/Pas mice requires the combined action of at least four genetic factors

(2012) L Chevallier et al.   GENES AND IMMUNITY

The R-spondin family of proteins: Emerging regulators of WNT signaling

(2012) Yong-Ri Jin et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A novel murine infection model for Shiga toxin–producing Escherichia coli

(2012) Emily M. Mallick et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: B Cells Are Essential for Protective Immunity against Salmonella Independent of Antibody Secretion

(2012) M. R. Nanton et al.   JOURNAL OF IMMUNOLOGY

Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa

(2012) Nicholas A Feasey et al.   LANCET

A non-invasive in vivo imaging system to study dissemination of bioluminescent Yersinia pestis CO92 in a mouse model of pneumonic plague

(2012) Jian Sha et al.   MICROBIAL PATHOGENESIS

Beyond an AFLP genome scan towards the identification of immune genes involved in plague resistance inRattus rattusfrom Madagascar

(2012) C. Tollenaere et al.   MOLECULAR ECOLOGY

Recurrent R-spondin fusions in colon cancer

(2012) Somasekar Seshagiri et al.   NATURE

Quantitative RT-PCR profiling of the Rabbit Immune Response: Assessment of Acute Shigella flexneri Infection

(2012) Pamela Schnupf et al.   PLoS One

Imaging of Bubonic Plague Dynamics by In Vivo Tracking of Bioluminescent Yersinia pestis

(2012) Toan Nham et al.   PLoS One

A Novel ENU-Mutation in Ankyrin-1 Disrupts Malaria Parasite Maturation in Red Blood Cells of Mice

(2012) Andreas Greth et al.   PLoS One

Salmonellosis in cattle: Advantages of being an experimental model

(2012) Luciana F. Costa et al.   RESEARCH IN VETERINARY SCIENCE

Opposing Roles for Interferon Regulatory Factor-3 (IRF-3) and Type I Interferon Signaling during Plague

(2012) Ami A. Patel et al.   PLoS Pathogens

Typhoid fever and paratyphoid fever: Systematic review to estimate global morbidity and mortality for 2010

(2012) Geoffrey C. Buckle et al.   Journal of Global Health

Chemokine Receptor CXCR2 Mediates Bacterial Clearance Rather Than Neutrophil Recruitment in a Murine Model of Pneumonic Plague

(2011) Nicholas A. Eisele et al.   AMERICAN JOURNAL OF PATHOLOGY

Colonic microbiota alters host susceptibility to infectious colitis by modulating inflammation, redox status, and ion transporter gene expression

(2011) S. Ghosh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Identification and characterization of Cri1, a locus controlling mortality during Citrobacter rodentium infection in mice

(2011) E Diez et al.   GENES AND IMMUNITY

Early Systemic Bacterial Dissemination and a Rapid Innate Immune Response Characterize Genetic Resistance to Plague of SEG Mice

(2011) Christian E. Demeure et al.   JOURNAL OF INFECTIOUS DISEASES

Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and typhoid susceptibility in Asian Malay population in Malaysia

(2011) Saatheeyavaane Bhuvanendran et al.   MICROBES AND INFECTION

Enteropathogenic and enterohaemorrhagic Escherichia coli: even more subversive elements

(2011) Alexander R. C. Wong et al.   MOLECULAR MICROBIOLOGY

Identification of an innate T helper type 17 response to intestinal bacterial pathogens

(2011) Kaoru Geddes et al.   NATURE MEDICINE

Malaria impairs resistance to Salmonella through heme- and heme oxygenase–dependent dysfunctional granulocyte mobilization

(2011) Aubrey J Cunnington et al.   NATURE MEDICINE

Identification of the bile salt binding site on ipad from Shigella flexneri and the influence of ligand binding on IpaD structure

(2011) Michael L. Barta et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Humanized mice forSalmonellatyphiinfection: new tools for an old problem

(2011) M. Firoz Mian et al.   Virulence

The Global Burden of NontyphoidalSalmonellaGastroenteritis

(2010) Shannon E. Majowicz et al.   CLINICAL INFECTIOUS DISEASES

Mus spretus SEG/Pas mice resist virulent Yersinia pestis, under multigenic control

(2010) C Blanchet et al.   GENES AND IMMUNITY

N-Ethyl-N-Nitrosourea-Induced Mutation in Ubiquitin-Specific Peptidase 18 Causes Hyperactivation of IFN-   Signaling and Suppresses STAT4-Induced IFN-  Production, Resulting in Increased Susceptibility to Salmonella Typhimurium

(2010) E. Richer et al.   JOURNAL OF IMMUNOLOGY

Revisiting Human IL-12Rβ1 Deficiency

(2010) Ludovic de Beaucoudrey et al.   MEDICINE

AFLP genome scan in the black rat (Rattus rattus) from Madagascar: detecting genetic markers undergoing plague-mediated selection

(2010) C. TOLLENAERE et al.   MOLECULAR ECOLOGY

Neutrophils Are Resistant to Yersinia YopJ/P-Induced Apoptosis and Are Protected from ROS-Mediated Cell Death by the Type III Secretion System

(2010) Justin L. Spinner et al.   PLoS One

Humanized nonobese diabetic-scid IL2r null mice are susceptible to lethal Salmonella Typhi infection

(2010) S. J. Libby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification by PCR of Non-typhoidal Salmonella enterica Serovars Associated with Invasive Infections among Febrile Patients in Mali

(2010) Sharon M. Tennant et al.   PLoS Neglected Tropical Diseases

Model Systems to Study Plague Pathogenesis and Develop New Therapeutics

(2010) Matthew B. Lawrenz   Frontiers in Microbiology

Pathogenesis and treatment of Shiga toxin-producing Escherichia coli infections

(2009) Antonio Serna et al.   CURRENT OPINION IN GASTROENTEROLOGY

Genetics of susceptibility to infection with enteric pathogens

(2009) Jose Flores et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Comparative Analysis of the Locus of Enterocyte Effacement and Its Flanking Regions

(2009) D. Muller et al.   INFECTION AND IMMUNITY

Yersinia pestis Can Reside in Autophagosomes and Avoid Xenophagy in Murine Macrophages by Preventing Vacuole Acidification

(2009) C. Pujol et al.   INFECTION AND IMMUNITY

Human genetics of infectious diseases: between proof of principle and paradigm

(2009) Alexandre Alcaïs et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic deficiencies of innate immune signalling in human infectious disease

(2009) Esther van de Vosse et al.   LANCET INFECTIOUS DISEASES

Non-typhoidal Salmonella bacteraemia: Epidemiology, clinical characteristics and its' association with severe immunosuppression

(2009) Amreeta Dhanoa et al.   Annals of Clinical Microbiology and Antimicrobials

Stem Cells, Self-Renewal, and Differentiation in the Intestinal Epithelium

(2008) Laurens G. van der Flier et al.   Annual Review of Physiology

Influence of Host Interleukin-10 Polymorphisms on Development of Traveler's Diarrhea Due to Heat-Labile Enterotoxin-Producing Escherichia coli in Travelers from the United States Who Are Visiting Mexico

(2008) J. Flores et al.   Clinical and Vaccine Immunology

Molecular Pathogenesis of Shigella spp.: Controlling Host Cell Signaling, Invasion, and Death by Type III Secretion

(2008) G. N. Schroeder et al.   CLINICAL MICROBIOLOGY REVIEWS

Substrains of 129 Mice Are Resistant to Yersinia pestis KIM5: Implications for Interleukin-10-Deficient Mice

(2008) J. K. Turner et al.   INFECTION AND IMMUNITY

The Resistance of BALB/cJ Mice to Yersinia pestis Maps to the Major Histocompatibility Complex of Chromosome 17

(2008) J. K. Turner et al.   INFECTION AND IMMUNITY

Interaction between Yersinia pestis and the Host Immune System

(2008) B. Li et al.   INFECTION AND IMMUNITY

CCR5 polymorphism and plague resistance in natural populations of the black rat in Madagascar

(2008) C. Tollenaere et al.   INFECTION GENETICS AND EVOLUTION

VirulentShigella flexnerisubverts the host innate immune response through manipulation of antimicrobial peptide gene expression

(2008) Brice Sperandio et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Salmonella infections in immunocompromised adults

(2008) Melita A. Gordon   JOURNAL OF INFECTION

Characterization of the rat pneumonic plague model: infection kinetics following aerosolization of Yersinia pestis CO92

(2008) Stacy L. Agar et al.   MICROBES AND INFECTION

Characterization of a mouse model of plague after aerosolization of Yersinia pestis CO92

(2008) S. L. Agar et al.   MICROBIOLOGY-SGM

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE

Forward Genetic Dissection of Immunity to Infection in the Mouse

(2007) S.M. Vidal et al.   Annual Review of Immunology