Article
Multidisciplinary Sciences
Chang Liu, Naoya Morimoto, Lan Jiang, Sohei Kawahara, Takako Noritomi, Hideaki Yokoyama, Koichi Mayumi, Kohzo Ito
Summary: The study introduces a damageless reinforcement strategy for hydrogels using strain-induced crystallization, which significantly enhances the toughness and enables almost 100% rapid recovery of extension energy.
Article
Chemistry, Physical
JiHyeon Hwang, Yujin Cha, Luis Ramos, Tianyu Zhu, Leman Buzoglu Kurnaz, Chuanbing Tang
Summary: Tough double-network metallopolymer antibacterial hydrogels were prepared through dual polymerization, exhibiting high compressive stress and antimicrobial efficacy.
CHEMISTRY OF MATERIALS
(2022)
Article
Polymer Science
Xiang Ni, Zhen Yang, Jianyu Li
Summary: Tough adhesive hydrogels have high resistance against both cohesion and adhesion failure, but their fracture properties may deteriorate when they swell upon exposure to water. The correlation between polymer fraction and fracture properties of tough adhesive hydrogels is still largely unexplored. This study investigates how cohesion and adhesion energies of tough adhesive hydrogels evolve with the swelling process, showing a scaling law of these quantities as a function of the polymer fraction. The results from scaling analysis and computational study suggest that the scaling of shear modulus plays a key role in this relationship, which can provide guidelines for the development of next-generation tough adhesive hydrogels.
Article
Chemistry, Multidisciplinary
Matteo Hirsch, Alvaro Charlet, Esther Amstad
Summary: Many soft natural tissues possess unique mechanical properties achieved through complex interactions between structure and composition. To address the lack of control in soft synthetic materials, a novel 3D printing approach called double network granular hydrogels (DNGHs) has been introduced. These DNGHs are stiff enough to support high tensile loads and significantly tougher than pure polymeric networks. This ink allows for the printing of strong and tough objects with high shape fidelity, opening up new possibilities for soft robotic applications.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Zhen Yang, Zhenwei Ma, Shiyu Liu, Jianyu Li
Summary: This study investigates the adhesion between tough hydrogels and various tissues through both experimental and computational methods, revealing a quantitative dependence of adhesion on the elastic modulus and dissipative properties of tissues. The findings provide insights for the development of tissue-specific adhesives for precision and personalized medicine.
MECHANICS OF MATERIALS
(2021)
Article
Materials Science, Multidisciplinary
Yong Liu, Yang Chen, Jie Zhu, Mengze Lu, Chuanxia Jiang, Zhiwei Fan, Taolin Sun
Summary: In this study, we investigated the mechanical behavior of tough and viscoelastic hydrogels under multiaxial stretching. The hydrogels exhibited higher mechanical properties and energy dissipation under equal biaxial stretching due to the greater contribution of hydrogen bonds. Additionally, the relaxation of dynamic hydrogen bonds in the hydrogels only depended on stretching time, regardless of the elongation ratio and stretching modes.
INTERNATIONAL JOURNAL OF SMART AND NANO MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Donghao Zhao, Yide Liu, Binhong Liu, Zhe Chen, Guodong Nian, Shaoxing Qu, Wei Yang
Summary: A new strategy for formulating hydrogel inks has been proposed to enable printing of strong and tough particle-based double-network hydrogels of arbitrary shapes without the need for any rheological modifiers. The hydrogel inks consist of microgels and a hydrogel precursor, which regulate the rheological properties of the ink and enable direct printing. This approach allows for the 3D printing of multifunctional hydrogel structures with high mechanical performance and strong adhesion to diverse materials, opening up new possibilities for applications in tissue engineering and soft robotics.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Puskal Kunwar, Bianca Louise Andrada, Arun Poudel, Zheng Xiong, Ujjwal Aryal, Zachary J. J. Geffert, Sajag Poudel, Daniel Fougnier, Ivan Gitsov, Pranav Soman
Summary: We introduce a new method to shape double-network (DN) hydrogels into customized 3D structures with superior mechanical properties. This method involves optimizing a prepolymer formulation containing acrylamide and κ-carrageenan to create tough DN hydrogels. We use a TOPS system to photopolymerize the primary acrylamide network, while cooling generates the secondary κ-carrageenan network, resulting in highly resilient DN hydrogel structures. These 3D structures exhibit high stress and strain under tension, as well as high compression stress and strain, with excellent recovery rates. Furthermore, we demonstrate the potential of this technology by printing a flexible axicon lens that can dynamically tune a Bessel beam.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Review
Polymer Science
Hai Xin
Summary: This review focuses on the mechanical toughness and structures of double-network (DN) hydrogels, discussing toughening mechanisms, damage recoverability, stress relaxation, and biomedical applications. While covalently cross-linked hydrogels are tough but damage-irreversible, physically cross-linked hydrogels are damage-recoverable but exhibit mechanical instability, posing a significant challenge for future research studies.
Article
Engineering, Mechanical
Xuelian Zhang, Junjie Liu, Jian Li, Zhihong Liang, Han Jiang, Guozheng Kang, Qianhua Kan
Summary: This study investigates the stress-controlled cyclic fatigue behavior of a double-network tough hydrogel, considering the effects of peak stress, loading rate, peak stress holding time, and environmental relative humidity. The results show that peak stress, humidity, and stress holding time affect the peak, valley, and ratcheting stretch, as well as the apparent modulus of the hydrogel. However, stress rate has a reverse effect on these parameters. The experimental results can be explained by the competition between the unzipping of ionic bonds and water loss during the fatigue test, revealing the ratcheting behavior of double-network tough hydrogels and inspiring further studies on other tough hydrogels' fatigue behavior.
EXTREME MECHANICS LETTERS
(2023)
Article
Engineering, Biomedical
Yuwan Huang, Pavithra B. Jayathilaka, Md Shariful Islam, Carina B. Tanaka, Meredith N. Silberstein, Kristopher A. Kilian, Jamie J. Kruzic
Summary: This study evaluated the mechanical and biological properties of hybrid double network (DN) hydrogels and found that the monomer molecular weight and structure of polyethylene glycol (PEG) affected the mechanical properties. The alginate network played an important role in the DN hydrogel, and showed potential in guiding musculoskeletal differentiation. These findings are significant for the design of hydrogels with controllable properties.
ACTA BIOMATERIALIA
(2022)
Article
Multidisciplinary Sciences
Bin Xue, Zoobia Bashir, Yachong Guo, Wenting Yu, Wenxu Sun, Yiran Li, Yiyang Zhang, Meng Qin, Wei Wang, Yi Cao
Summary: In this study, hydrogels with hierarchical structures and hidden length are reported, which enable the dissipation of mechanical load and improve the mechanical performance of the hydrogels.
NATURE COMMUNICATIONS
(2023)
Article
Materials Science, Composites
Dan Xie, Wenwen Hou, Xiaodan Wang, Wenxin Fan, Xiaohui Zhang, Dong Wang, Jianzhuang Shi, Libang Guo, Kunyan Sui
Summary: A simple and generable strategy of folding polymer chains in poor solvent is presented to fabricate high-performance sensors. The combination of chain folding and double-network structure greatly improves the stress buffering and energy dissipation capacity of hydrogels. The resulting hydrogels exhibit ultra-high strength, stretchability, and toughness, making them ideal strain sensors with a broad work window.
COMPOSITES COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Wei Cui, Ruijie Zhu, Yong Zheng, Qifeng Mu, Menghan Pi, Qiang Chen, Rong Ran
Summary: Utilizing a phase-separation strategy, non-adhesive hydrogels can be transformed into tough glues for various solid surfaces without the need for chemical treatment. This method significantly increases the polymer volume fraction at the gel surface and in the bulk, enhancing adhesion between the hydrogel and solid surfaces.
JOURNAL OF MATERIALS CHEMISTRY A
(2021)
Article
Engineering, Mechanical
Zhi-Yong Yin, Xiao-wei Chen
Summary: This study numerically reveals three typical fracture modes of explosively-driven metal shells and investigates the influencing factors of different fracture modes through experimental data and dimensional analysis.
INTERNATIONAL JOURNAL OF IMPACT ENGINEERING
(2024)
Article
Biochemistry & Molecular Biology
Zannatul Ferdous, Jean-Emmanuel Clement, Jian Ping Gong, Shinya Tanaka, Tamiki Komatsuzaki, Masumi Tsuda
Summary: Cancer stem cells (CSCs) are a crucial target for curing cancer, but their characteristics are difficult to elucidate due to the variability of CSC markers and expressions. This study examined the relationship between stemness elevation and geometrical features of single cells, revealing a strong correlation between morphological differences and stemness elevation.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2023)
Article
Polymer Science
Xueyu Li, Feng Luo, Tao Lin Sun, Kunpeng Cui, Reina Watanabe, Tasuku Nakajima, Jian Ping Gong
Summary: Understanding the mechanical behaviors of tough hydrogels with dynamic bonds in saline solution is crucial for applications, especially in the biomedical field.
Article
Polymer Science
Anais Giustiniani, Muhammad Ilyas, Tsutomu Indei, Jian Ping Gong
Summary: This study investigates the dynamic mechanical properties of PDGI/PAAm gels and the energy dissipation mechanisms involved. The relaxation process is found to be caused by the rupture of physical bonds within the PDGI bilayers, with a characteristic time of approximately 10 seconds.
Article
Engineering, Mechanical
Jikun Wang, Kunpeng Cui, Bangguo Zhu, Jian Ping Gong, Chung-Yuen Hui, Alan T. Zehnder
Summary: Relaxation experiments were conducted on single edge notch tension (SENT) and T shape specimens made of various polyampholyte (PA) hydrogels. These specimens have the common feature of containing regions with high and low stress/strain, allowing us to investigate the load transfer mechanisms between permanent and dynamic networks of different strengths, which are related to viscoelastic behavior. PA gels exhibit non-linear viscoelasticity, with time-dependent behavior controlled by the breaking and reforming of ionic bonds in the dynamic network. Contrary to the prediction of linear viscoelastic theory, the displacement and strain fields during stress relaxation change in a complex manner depending on the strength of the dynamic bonds and the observation time window. These experimental findings are explained by a non-linear viscoelastic model. Additional physical insights are obtained by studying the non-linear rheology of dynamic bonds or stickers. Our results demonstrate that modifying the strength of dynamic bonds can control the load transfer between networks.
EXTREME MECHANICS LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Yong Zheng, Julong Jiang, Mingoo Jin, Daiyo Miura, Fei Xue Lu, Koji Kubota, Tasuku Nakajima, Satoshi Maeda, Hajime Ito, Jian Ping Gong
Summary: In this study, a novel strategy for real-time visualization of mechanochemical damages in hydrogels was developed using prefluorescent probes via oxygen-relayed free-radical trapping. This method allows for the detection of mechanochemical damages in hydrogels made from brittle networks of varied chemical structures, without introducing any chemical structural changes in the materials.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Polymer Science
Martin Frauenlob, Honglei Guo, Takayuki Kurokawa, Jian Ping Gong
Summary: Understanding the molecular origin of surface charges in double network hydrogels is crucial for their applications. This paper investigates the incorporation of unreacted monomers from the first network into the second network, which results in an increase in surface charge and affects the repulsive/adhesive properties. The authors propose a method to remove unreacted monomers and modulate the surface charge density of double network hydrogels.
Article
Polymer Science
Tasuku Nakajima, Kei Mito, Jian Ping Gong
Summary: MC-PDGI/PAAm gels are cylindrical composite gels with PDGI as a polymerized lipid in a multilayer tubular shape within a PAAm network. The unique feature of these gels is their super-anisotropic swelling, with increased diameter but decreased length. Swelling and X-ray diffraction experiments reveal that the elasticity of PDGI bilayers dominates the swelling anisotropy. Understanding the equation of state of the gel is crucial for controlling the super-anisotropic swelling and applications as anisotropic actuation devices.
Article
Multidisciplinary Sciences
Chika Imaoka, Tasuku Nakajima, Tsutomu Indei, Masaya Iwata, Wei Hong, Alba Marcellan, Jian Ping Gong
Summary: In this study, it was found that highly extended double-network hydrogels exhibit abnormal inverse mechanical-swelling coupling, with extension causing deswelling and drying causing softening. Theoretical models were established to reproduce the complex mechanical and swelling trends of the highly deformed hydrogels. These findings contribute to the understanding of the mechanics of rubber-like materials at their ultimate deformation and fracture limit.
Article
Chemistry, Multidisciplinary
Milena Lama, Jian Ping Gong
Summary: It is found that the formation of fibrous morphology of bentonite nanoparticles is closely related to the presence of organic cations surfactant. Under the action of organic cationic surfactant, the fibrous morphology of the nanoparticles can be well formed.
Article
Chemistry, Multidisciplinary
Gumi Wei, Yumeko Kudo, Takahiro Matsuda, Zhi Jian Wang, Qi Feng Mu, Daniel R. King, Tasuku Nakajima, Jian Ping Gong
Summary: Double-network (DN) gels are mechanochemical materials with dynamic structures that can be remodeled during use. A circulatory system was constructed to continuously supply chemicals to channel-containing DN hydrogels, enabling continuous remodelling and growth in response to mechanical stimuli. The chemical supply facilitated modulation of the mechanical enhancement of the DN gels and achieved muscle-like strengthening under repeated mechanical training in deoxygenated air. The kinetics of polymer growth and strengthening in DN gels were also studied, revealing unique features of mechanochemical reactions.
MATERIALS HORIZONS
(2023)
Article
Materials Science, Multidisciplinary
Shou Ohmura, Tasuku Nakajima, Masahiro Yoshida, Jian Ping Gong
Summary: The hierarchical anisotropy of a biotissue plays a critical role in its functions. Soft and wet synthetic hydrogels with biotissue-like anisotropy have been extensively studied, but most lack mechanical toughness. This paper presents hybrid double-network hydrogels made from a squid mantle and a synthetic polymer, which exhibit anisotropy and excellent toughness due to their unique composite structure. This strategy provides a general method for preparing hydrogels with elaborate anisotropy and derived functions.
NPG ASIA MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Soichiro Hiraiwa, Thanh-Tam Mai, Katsuhiko Tsunoda, Kenji Urayama
Summary: This study reveals the strain hardening due to strain-induced crystallization (SIC) in both cross-linked natural rubber (NR) and its synthetic analogue (IR) under planar extension. The research shows that evident strain hardening due to SIC is observed in both stretching and constrained directions when the stretch exceeds a critical value. The study also finds a distinct minimum in the nominal stress ratio as a function of stretch, indicating a reversed relationship between the increment of stress in the stretching and constrained directions. Furthermore, the investigation provides valuable insights for predicting the mechanical response of SIC rubber under different deformation conditions.
Article
Chemistry, Multidisciplinary
Javier Troyano, Fuerkaiti Tayier, Phitchayapha Phattharaphuti, Takuma Aoyama, Kenji Urayama, Shuhei Furukawa
Summary: This study presents a self-gelation approach based on metal-organic polyhedra (MOPs) that allows for the reversible assembly into nanoparticles and colloidal gels through charge manipulation. Furthermore, the simplicity of this method is demonstrated by synthesizing MOP-based gels via a one-pot synthetic approach. The research highlights the potential application of charge manipulation in the formation of supramolecular gels and porous aerogels based on MOPs.
Article
Chemistry, Physical
Atsushi Yamamoto, Takumi Inui, Daisuke Suzuki, Kenji Urayama
Summary: We investigated the yielding behavior of dilute poly(N-isopropyl acrylamide-co-fumaric acid) (PNIPAM-FAc) colloidal gels obtained above the volume phase transition temperature. We found that yielding occurs when the applied strain exceeds a specific threshold, requiring a finite, stress-independent delay time. This behavior is distinct from previous findings on delayed yielding in other colloidal gels.