The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

(2017) Yannick Simoni et al.   IMMUNITY

The heterogeneous landscape of ALK negative ALCL

(2017) Elisabetta Mereu et al.   Oncotarget

The 2016 revision of the World Health Organization classification of lymphoid neoplasms

(2016) S. H. Swerdlow et al.   BLOOD

Distinct Gene Regulatory Pathways for Human Innate versus Adaptive Lymphoid Cells

(2016) Olivia I. Koues et al.   CELL

RORγt inhibitors as potential back-ups for the phase II candidate VTP-43742 from Vitae Pharmaceuticals: patent evaluation of WO2016061160 and US20160122345

(2016) Christian Gege   EXPERT OPINION ON THERAPEUTIC PATENTS

Abrupt Relapse of ALK-Positive Lymphoma after Discontinuation of Crizotinib

(2016) Carlo Gambacorti-Passerini et al.   NEW ENGLAND JOURNAL OF MEDICINE

Phase 3 Trials of Ixekizumab in Moderate-to-Severe Plaque Psoriasis

(2016) Kenneth B. Gordon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress

(2016) Tim I. M. Malcolm et al.   Nature Communications

Insights into the Pathogenesis of Anaplastic Large-Cell Lymphoma through Genome-wide DNA Methylation Profiling

(2016) Melanie R. Hassler et al.   Cell Reports

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

(2015) I. Scarfo et al.   BLOOD

Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma

(2015) Ramona Crescenzo et al.   CANCER CELL

Group 3 innate lymphoid cells (ILC3s): Origin, differentiation, and plasticity in humans and mice

(2015) Elisa Montaldo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Essential role of IRF4 and MYC signaling for survival of anaplastic large cell lymphoma

(2014) Andre Weilemann et al.   BLOOD

Inhibiting RORγt/Th17 axis for autoimmune disorders

(2014) Fujio Isono et al.   DRUG DISCOVERY TODAY

Small-Molecule RORγt Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms

(2014) Sheng Xiao et al.   IMMUNITY

Crizotinib in Advanced, Chemoresistant Anaplastic Lymphoma Kinase–Positive Lymphoma Patients

(2014) Carlo Gambacorti Passerini et al.   JNCI-Journal of the National Cancer Institute

PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma

(2013) M. Boi et al.   BLOOD

RORγt+ Innate Lymphoid Cells Acquire a Proinflammatory Program upon Engagement of the Activating Receptor NKp44

(2013) Timor Glatzer et al.   IMMUNITY

Identification of SR2211: A Potent Synthetic RORγ-Selective Modulator

(2012) Naresh Kumar et al.   ACS Chemical Biology

Pathogenesis of Human B Cell Lymphomas

(2012) Arthur L. Shaffer et al.   Annual Review of Immunology

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma

(2012) L. Agnelli et al.   BLOOD

A Validated Regulatory Network for Th17 Cell Specification

(2012) Maria Ciofani et al.   CELL

Compensatory dendritic cell development mediated by BATF–IRF interactions

(2012) Roxane Tussiwand et al.   NATURE

BATF–JUN is critical for IRF4-mediated transcription in T cells

(2012) Peng Li et al.   NATURE

PDGFR blockade is a rational and effective therapy for NPM-ALK–driven lymphomas

(2012) Daniela Laimer et al.   NATURE MEDICINE

A Genomic Regulatory Element That Directs Assembly and Function of Immune-Specific AP-1-IRF Complexes

(2012) E. Glasmacher et al.   SCIENCE

miR-135b mediates NPM-ALK-driven oncogenicity and renders IL-17-producing immunophenotype to anaplastic large cell lymphoma

(2011) H. Matsuyama et al.   BLOOD

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity

(2011) Jun R. Huh et al.   NATURE

Malignant pirates of the immune system

(2011) Lixin Rui et al.   NATURE IMMUNOLOGY

A novel role for IL-22R1 as a driver of inflammation

(2010) R. Savan et al.   BLOOD

AP-1 — The Jun proteins: Oncogenes or tumor suppressors in disguise?

(2010) Eitan Shaulian   CELLULAR SIGNALLING

Identification of differential and functionally active miRNAs in both anaplastic lymphoma kinase (ALK)+ and ALK- anaplastic large-cell lymphoma

(2010) O. Merkel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular signatures to improve diagnosis in peripheral T-cell lymphoma and prognostication in angioimmunoblastic T-cell lymphoma

(2009) J. Iqbal et al.   BLOOD

Gene expression profiling of isolated tumour cells from anaplastic large cell lymphomas: insights into its cellular origin, pathogenesis and relation to Hodgkin lymphoma

(2009) S Eckerle et al.   LEUKEMIA

The AP-1 transcription factor Batf controls TH17 differentiation

(2009) Barbara U. Schraml et al.   NATURE

Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma

(2009) S. Mathas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aberrant expression of IL-22 receptor 1 and autocrine IL-22 stimulation contribute to tumorigenicity in ALK+ anaplastic large cell lymphoma

(2008) J Dien Bard et al.   LEUKEMIA