First-in-class oral small molecule inhibitor of the tyrosine kinase ROR1 (KAN0439834) induced significant apoptosis of chronic lymphocytic leukemia cells

Preclinical development of novel humanised ROR1 targeting chimeric antigen receptor T cells and bispecific T-cell engagers

(2017) Satyen Gohil et al.   LANCET

Cirmtuzumab inhibits Wnt5a-induced Rac1 activation in chronic lymphocytic leukemia treated with ibrutinib

(2016) J Yu et al.   LEUKEMIA

Modeling the chronic lymphocytic leukemia microenvironment in vitro

(2016) Kyle Crassini et al.   LEUKEMIA & LYMPHOMA

Identification of Noncanonical Wnt Receptors Required for Wnt-3a-Induced Early Differentiation of Human Neural Stem Cells

(2016) Nora Bengoa-Vergniory et al.   MOLECULAR NEUROBIOLOGY

Novel Agents in the Treatment of Chronic Lymphocytic Leukemia: A Review About the Future

(2015) Anjali Varma Desai et al.   Clinical Lymphoma Myeloma & Leukemia

The receptor tyrosine kinase ROR1 – An oncofetal antigen for targeted cancer therapy

(2014) Mohammad Hojjat-Farsangi et al.   SEMINARS IN CANCER BIOLOGY

The Tyrosine Kinase Receptor ROR1 Is Constitutively Phosphorylated in Chronic Lymphocytic Leukemia (CLL) Cells

(2013) Mohammad Hojjat-Farsangi et al.   PLoS One

NKX2-1/TITF1/TTF-1-Induced ROR1 Is Required to Sustain EGFR Survival Signaling in Lung Adenocarcinoma

(2012) Tomoya Yamaguchi et al.   CANCER CELL

Monoclonal antibodies against ROR1 induce apoptosis of chronic lymphocytic leukemia (CLL) cells

(2012) A H Daneshmanesh et al.   LEUKEMIA

ROR1 Is Expressed in Human Breast Cancer and Associated with Enhanced Tumor-Cell Growth

(2012) Suping Zhang et al.   PLoS One

Silencing of ROR1 and FMOD with siRNA results in apoptosis of CLL cells

(2010) Aniruddha Choudhury et al.   BRITISH JOURNAL OF HAEMATOLOGY