Isolation and genome sequencing of individual circulating tumor cells using hydrogel encapsulation and laser capture microdissection

Platforms for Single-Cell Collection and Analysis

(2018) Lukas Valihrach et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Integration of pan-cancer transcriptomics with RPPA proteomics reveals mechanisms of epithelial-mesenchymal transition

(2018) Simon Koplev et al.   PLoS Computational Biology

Treatment Outcomes and Tumor Loss of Heterozygosity in Germline DNA Repair–deficient Prostate Cancer

(2017) Matti Annala et al.   EUROPEAN UROLOGY

Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer

(2017) Alexander W Wyatt et al.   JNCI-Journal of the National Cancer Institute

Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer

(2017) Alexander W Wyatt et al.   JNCI-Journal of the National Cancer Institute

Mutation Analysis of Cell-Free DNA and Single Circulating Tumor Cells in Metastatic Breast Cancer Patients with High Circulating Tumor Cell Counts

(2016) Jacqueline A. Shaw et al.   CLINICAL CANCER RESEARCH

Reality of Single Circulating Tumor Cell Sequencing for Molecular Diagnostics in Pancreatic Cancer

(2016) Colin M. Court et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Gene expression profiling of single circulating tumor cells in ovarian cancer - Establishment of a multi-marker gene panel

(2016) Christina Blassl et al.   Molecular Oncology

Continuous Flow Deformability-Based Separation of Circulating Tumor Cells Using Microfluidic Ratchets

(2016) Emily S. Park et al.   Small

Technologies for Single-Cell Isolation

(2015) Andre Gross et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Circulating Tumor Cell Biomarker Panel As an Individual-Level Surrogate for Survival in Metastatic Castration-Resistant Prostate Cancer

(2015) Howard I. Scher et al.   JOURNAL OF CLINICAL ONCOLOGY

Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue

(2015) Colin S Cooper et al.   NATURE GENETICS

High-Density Dielectrophoretic Microwell Array for Detection, Capture, and Single-Cell Analysis of Rare Tumor Cells in Peripheral Blood

(2015) Atsushi Morimoto et al.   PLoS One

Heterogeneity of PIK3CA mutational status at the single cell level in circulating tumor cells from metastatic breast cancer patients

(2014) Marta Pestrin et al.   Molecular Oncology

Whole-exome sequencing of circulating tumor cells provides a window into metastatic prostate cancer

(2014) Jens G Lohr et al.   NATURE BIOTECHNOLOGY

Single-cell RNA-seq: advances and future challenges

(2014) Antoine-Emmanuel Saliba et al.   NUCLEIC ACIDS RESEARCH

Rapid Phenotypic and Genomic Change in Response to Therapeutic Pressure in Prostate Cancer Inferred by High Content Analysis of Single Circulating Tumor Cells

(2014) Angel E. Dago et al.   PLoS One

Dielectrophoretic Capture and Genetic Analysis of Single Neuroblastoma Tumor Cells

(2014) Erica L. Carpenter et al.   Frontiers in Oncology

High-Purity Prostate Circulating Tumor Cell Isolation by a Polymer Nanofiber-Embedded Microchip for Whole Exome Sequencing

(2013) Libo Zhao et al.   ADVANCED MATERIALS

Semiautomated isolation and molecular characterisation of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting

(2013) D J E Peeters et al.   BRITISH JOURNAL OF CANCER

Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing

(2013) E. Heitzer et al.   CANCER RESEARCH

Punctuated Evolution of Prostate Cancer Genomes

(2013) Sylvan C. Baca et al.   CELL

Are morphological criteria sufficient for the identification of circulating tumor cells in renal cancer?

(2013) Amin El-Heliebi et al.   Journal of Translational Medicine

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

(2012) Christopher E Barbieri et al.   NATURE GENETICS

High-resolution analyses of copy number changes in disseminated tumor cells of patients with breast cancer

(2011) Randi R. Mathiesen et al.   INTERNATIONAL JOURNAL OF CANCER

Tumour evolution inferred by single-cell sequencing

(2011) Nicholas Navin et al.   NATURE

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

Characterization of KRAS Rearrangements in Metastatic Prostate Cancer

(2011) Xiao-Song Wang et al.   Cancer Discovery

Androgen receptor sequence and variations in several common prostate cancer cell lines

(2010) Caitlin E. Baum et al.   CANCER BIOLOGY & THERAPY

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing

(2010) D. Pflueger et al.   GENOME RESEARCH

Significant and Sustained Antitumor Activity in Post-Docetaxel, Castration-Resistant Prostate Cancer With the CYP17 Inhibitor Abiraterone Acetate

(2010) Alison H.M. Reid et al.   JOURNAL OF CLINICAL ONCOLOGY

Amplification of multiple genomic loci from single cells isolated by laser micro-dissection of tissues

(2008) Dan Frumkin et al.   BMC BIOTECHNOLOGY

Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer

(2008) J. S. de Bono et al.   CLINICAL CANCER RESEARCH

Relationship of Circulating Tumor Cells to Tumor Response, Progression-Free Survival, and Overall Survival in Patients With Metastatic Colorectal Cancer

(2008) Steven J. Cohen et al.   JOURNAL OF CLINICAL ONCOLOGY