New technologies for developing second generation retinal prostheses

A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina

(2017) Antoine Chaffiol et al.   MOLECULAR THERAPY

A fully organic retinal prosthesis restores vision in a rat model of degenerative blindness

(2017) José Fernando Maya-Vetencourt et al.   NATURE MATERIALS

Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration

(2017) Michiko Mandai et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cellular interfaces with hydrogen-bonded organic semiconductor hierarchical nanocrystals

(2017) Mykhailo Sytnyk et al.   Nature Communications

Restoring visual function to the blind retina with a potent, safe and long-lasting photoswitch

(2017) Ivan Tochitsky et al.   Scientific Reports

Stem Cell Therapies in Retinal Disorders

(2017) Aakriti Garg et al.   Cells

Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina

(2016) Abhishek Sengupta et al.   EMBO Molecular Medicine

Emerging therapies for inherited retinal degeneration

(2016) H. P. N. Scholl et al.   Science Translational Medicine

Cell-Based Therapy for Degenerative Retinal Disease

(2016) Marco Zarbin   TRENDS IN MOLECULAR MEDICINE

Characterization of a Polymer-Based, Fully Organic Prosthesis for Implantation into the Subretinal Space of the Rat

(2016) Maria Rosa Antognazza et al.   Advanced Healthcare Materials

Nanoparticles: A Challenging Vehicle for Neural Stimulation

(2016) Elisabetta Colombo et al.   Frontiers in Neuroscience

Surface Polarization Drives Photoinduced Charge Separation at the P3HT/Water Interface

(2016) Edoardo Mosconi et al.   ACS Energy Letters

Light-evoked hyperpolarization and silencing of neurons by conjugated polymers

(2016) Paul Feyen et al.   Scientific Reports

Restoring Light Sensitivity in Blind Retinae Using a Photochromic AMPA Receptor Agonist

(2015) L. Laprell et al.   ACS Chemical Neuroscience

Optogenetics

(2015) Jens Duebel et al.   CURRENT OPINION IN OPHTHALMOLOGY

Gene Therapy of Inherited Retinal Degenerations: Prospects and Challenges

(2015) Ivana Trapani et al.   HUMAN GENE THERAPY

Photovoltaic restoration of sight with high visual acuity

(2015) Henri Lorach et al.   NATURE MEDICINE

Photosensitivity of Neurons Enabled by Cell-Targeted Gold Nanoparticles

(2015) João L. Carvalho-de-Souza et al.   NEURON

Photothermal cellular stimulation in functional bio-polymer interfaces

(2015) Nicola Martino et al.   Scientific Reports

Optogenetic Approaches to Restoring Vision

(2015) Zhuo-Hua Pan et al.   Annual Review of Vision Science

Shedding Light on Living Cells

(2014) Maria Rosa Antognazza et al.   ADVANCED MATERIALS

Flexible Organic Electronics in Biology: Materials and Devices

(2014) Caizhi Liao et al.   ADVANCED MATERIALS

A review and update on the current status of retinal prostheses (bionic eye)

(2014) Y. H.- L. Luo et al.   BRITISH MEDICAL BULLETIN

Organic electronics meets biology

(2014) Guglielmo Lanzani   NATURE MATERIALS

Independent optical excitation of distinct neural populations

(2014) Nathan C Klapoetke et al.   NATURE METHODS

Noninvasive optical inhibition with a red-shifted microbial rhodopsin

(2014) Amy S Chuong et al.   NATURE NEUROSCIENCE

Restoring Visual Function to Blind Mice with a Photoswitch that Exploits Electrophysiological Remodeling of Retinal Ganglion Cells

(2014) Ivan Tochitsky et al.   NEURON

First-in-Human Trial of a Novel Suprachoroidal Retinal Prosthesis

(2014) Lauren N. Ayton et al.   PLoS One

Optogenetics, visual prosthesis and electrostimulation for retinal dystrophies

(2013) Sunir J. Garg et al.   CURRENT OPINION IN OPHTHALMOLOGY

A polymer optoelectronic interface restores light sensitivity in blind rat retinas

(2013) Diego Ghezzi et al.   Nature Photonics

Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS

(2013) K. Stingl et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Fighting Blindness with Microelectronics

(2013) E. Zrenner   Science Translational Medicine

Cortical responses elicited by photovoltaic subretinal prostheses exhibit similarities to visually evoked potentials

(2013) Yossi Mandel et al.   Nature Communications

Photovoltaic retinal prosthesis with high pixel density

(2012) Keith Mathieson et al.   Nature Photonics

Photochemical Restoration of Visual Responses in Blind Mice

(2012) Aleksandra Polosukhina et al.   NEURON

Interim Results from the International Trial of Second Sight's Visual Prosthesis

(2012) Mark S. Humayun et al.   OPHTHALMOLOGY

Infrared light excites cells by changing their electrical capacitance

(2012) Mikhail G. Shapiro et al.   Nature Communications

Control of optical properties through photochromism: a promising approach to photonics

(2011) A. Bianco et al.   Laser & Photonics Reviews

Retinal Prostheses: Current Clinical Results and Future Needs

(2011) James D. Weiland et al.   OPHTHALMOLOGY

A hybrid bioorganic interface for neuronal photoactivation

(2011) Diego Ghezzi et al.   Nature Communications

Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait

(2010) Alan F. Wright et al.   NATURE REVIEWS GENETICS

Subretinal electronic chips allow blind patients to read letters and combine them to words

(2010) E. Zrenner et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa

(2010) V. Busskamp et al.   SCIENCE

The relationship between visual resolution and cone spacing in the human fovea

(2009) Ethan A Rossi et al.   NATURE NEUROSCIENCE

Photochemical control of endogenous ion channels and cellular excitability

(2008) Doris L Fortin et al.   NATURE METHODS

Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis

(2008) Albert M. Maguire et al.   NEW ENGLAND JOURNAL OF MEDICINE