Article
Biology
Anda-Petronela Radan, Sophie Schneider, Jarmila A. Zdanowicz, Luigi Raio, Nando Mertineit, Johannes Thomas Heverhagen, Daniel Surbek
Summary: This study evaluated the long-term outcomes of 28 patients who underwent transcatheter pelvic arterial embolization (TAE) for severe postpartum hemorrhage between 2009 and 2018. The study suggests limited fertility in patients undergoing TAE with increased risk for miscarriage and recurrent PPH for those who conceive, highlighting the need for counseling.
Article
Biochemistry & Molecular Biology
Oyvind Hatlevik, Martin Jensen, Douglas Steinhauff, Xiaomei Wei, Eugene Huo, Jolanta Jedrzkiewicz, Joseph Cappello, Darwin Cheney, Hamidreza Ghandehari
Summary: Transcatheter arterial embolization using silk-elastinlike protein polymers (SELPs) as embolic agents is effective in locally blocking blood flow to tumors. The SELP embolic system can deeply penetrate target tissues and selectively embolize blood vessels, offering a better treatment option compared to current microparticle agents.
MACROMOLECULAR BIOSCIENCE
(2022)
Article
Pharmacology & Pharmacy
Xiaotian Zhao, Wanqiu Huang, Xufeng Li, Runxing Lin, Qiuxia Li, Jingmiao Wu, Zongjun Yu, Yanfang Zhou, Hong Huang, Mingguang Yu, Yugang Huang, Guodong Ye
Summary: The study successfully synthesized embolic microspheres from sucrose multi-allyl ether monomer using a novel photopolymerization technique. The microspheres demonstrated good biocompatibility and long-term embolic effects in rabbit models.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
(2021)
Article
Medicine, General & Internal
Shinhaeng Lee, Taehwan Kim, Seung Chul Han, Haeyong Pak, Han Ho Jeon
Summary: This study evaluated the clinical outcomes and prognostic factors of transcatheter arterial embolization (TAE) for acute gastrointestinal bleeding. The results showed that TAE is an effective, safe, and potentially lifesaving procedure for GI bleeding, with coagulopathy being a prognostic factor for rebleeding and mortality.
Article
Engineering, Biomedical
Li Liu, Xianxian Liang, Xiangxian Xu, Xiang Zhang, Jun Wen, Kun Chen, Xiaodan Su, Zhaogang Teng, Guangming Lu, Jian Xu
Summary: A new magnetic mesoporous embolic microsphere capable of loading drugs, blocking vessels, and being visualized on MRI has been developed for the treatment of liver cancer. In animal studies, this microsphere demonstrated effective inhibition of liver cancer cell growth and potential for use in TACE.
ACTA BIOMATERIALIA
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Maide Gokce Bekaroglu, Fuad Nurili, Ismail Caymaz, Ahmet Bas, Sevim Isci
Summary: The aim of this study was to prepare embolic hydroxyl ethyl cellulose (HEC)-polyvinyl prolidone (PVP)-magnetic particles suitable for TACE procedures, drug delivery, and magnetic hyperthermia. The particles demonstrated good embolization and drug delivery properties, with appropriate size and drug release time for localized chemotherapy at the tumor site. In vivo studies showed that the particles could be easily delivered through microcatheters and effectively embolize the target.
Article
Materials Science, Multidisciplinary
Maofeng Gong, Zhengli Liu, Jie Kong, Boxiang Zhao, Xu He, Jianping Gu, Haobo Su
Summary: Acute massive pancreaticoduodenal artery (PDA) hemorrhage is an urgent condition. We report our experience in transcatheter arterial embolization (TAE) using N-butyl-2 cyanoacrylate (NBCA) Glubran 2 for this condition. TAE with NBCA Glubran 2 plays an important role in controlling massive PDA hemorrhage, being minimally invasive, effective, relatively safe, and reducing the need for immediate traditional surgery.
FRONTIERS IN MATERIALS
(2022)
Article
Veterinary Sciences
Yuta Kawamura, Hiroki Itou, Akitomo Kida, Hiroki Sunkawa, Kenji Kawamura
Summary: This case demonstrates the effectiveness of transcatheter arterial embolization (TAE) for initial hemostasis and stabilization of conditions in animals with tumor-induced hemorrhage.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Surgery
Hyo-Cheol Kim, Yun Soo Jeong, Kichang Han, Gyoung Min Kim
Summary: The study aimed to evaluate the safety and clinical outcomes of transcatheter arterial embolization (TAE) via the cystic artery for treating patients with bleeding from the cystic artery. A retrospective study of 20 patients who underwent TAE via the cystic artery was conducted. Technical success was achieved in all cases, while clinical success rate was 70%. Complications such as ischemic cholecystitis and mortality were observed.
FRONTIERS IN SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Seong Ho Kim, Kichang Han, Ji Hoon Shin, Jinoo Kim, Dong Ho Hyun, Mi-Young Lee
Summary: This study retrospectively analyzed the angiographic findings and outcomes of repeat uterine artery embolization (UAE) for recurrent postpartum hemorrhage (PPH) in patients who had undergone UAE for PPH in the past. The results showed that the technical success rates of the first and second UAEs were 100% and 95.2%, respectively, and the clinical success rates were 85.7% and 95.2%. Obliteration of uterine arteries and formation of collateral arteries were common during the second UAEs.
EUROPEAN RADIOLOGY
(2023)
Article
Medicine, General & Internal
Samir R. R. Kapadia, Raj Makkar, Martin Leon, Mohamed Abdel-Wahab, Thomas Waggoner, Steffen Massberg, Wolfgang Rottbauer, Samuel Horr, Lars Sondergaard, Juhana Karha, Robert Gooley, Lowell Satler, Robert C. Stoler, Steven R. Messe, Suzanne J. Baron, Julia Seeger, Susheel Kodali, Amar Krishnaswamy, Vinod H. Thourani, Katherine Harrington, Stuart Pocock, Rodrigo Modolo, Dominic J. Allocco, Ian T. Meredith, Axel Linke, PROTECTED TAVR Investigators
Summary: Among patients with aortic stenosis undergoing transfemoral TAVR, the use of CEP did not have a significant effect on the incidence of periprocedural stroke, but on the basis of the 95% confidence interval around this outcome, the results may not rule out a benefit of CEP during TAVR.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Chemistry, Multidisciplinary
Xuqi Peng, Yating Zheng, Yi Xue, Xiaoliu Liang, Pan He, Hu Chen, Peng He, Yisheng Peng, Zhenwen Zhao, Yulun Chen, Xiran Gui, Lei Yang, Yongfu Xiong, Juan Lin, Yesi Shi, Chengchao Chu, Yang Zhang, Gang Liu
Summary: Transcatheter arterial ionic-embolization (TAIE) is a promising approach that disrupts intracellular ionic balance to inhibit tumor activity and invasion in treating hepatocellular carcinoma (HCC). The super-stable homogeneous embolic formulation lipiodol-sodium chloride (LSC) selectively deposits in HCC lesions and disrupts the cell's ionic balance, causing cell death without drug resistance. LSC treatment significantly hinders tumor cell migration and invasion by inducing cell swelling and remodeling the cytoskeleton.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Jingjie Hu, Hassan Albadawi, Zefu Zhang, Marcela A. Salomao, Seyda Gunduz, Suliman Rehman, Luciana D'Amone, Joseph L. Mayer, Fiorenzo Omenetto, Rahmi Oklu
Summary: A novel silk-based embolic material (SEM) has been developed and optimized for embolization and therapeutic drug delivery. In vitro studies show sustained release of drugs from SEM over 28 days, while in vivo experiments demonstrate successful embolization and drug delivery in porcine arteries. SEM has the potential to be a next-generation embolic agent for treating vascular diseases, including tumors.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Zefu Zhang, Hassan Albadawi, Richard J. Fowl, Izzet Altun, Marcela A. Salomao, Jama Jahanyar, Brian W. Chong, Joseph L. Mayer, Rahmi Oklu
Summary: Saccular aneurysms are outpouchings from artery walls and have limitations with current treatment options. A nanoclay-based hydrogel, called STH, is developed and shows promising results in preclinical studies, effectively treating saccular aneurysms and potentially changing medical practice.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Y. Lun, Y. Zhou, Q. Li, P. Chen, Y. Huang, G. Ye
Summary: In this study, Fe3O4 sucrose allyl ether (Fe3O4@SAE) magnetic microspheres were prepared using photodriven radical-mediated cyclization reaction (PRMC). These microspheres showed good morphology, performance, and cell compatibility, making them suitable for use as embolic agents.
MATERIALS TODAY CHEMISTRY
(2022)
