Article
Cardiac & Cardiovascular Systems
Chang Hee Kwon, Woohyeun Kim, Jeong-Hun Shin, Chan Joo Lee, Hyeon-Chang Kim, Si-Hyuck Kang, Mi-Hyang Jung, Dae-Hee Kim, Ju-Hee Lee, Hack Lyoung Kim, Hyue Mee Kim, In Jeong Cho, Iksung Cho, Dae Ryong Kang, Hae-Young Lee, Wook-Jin Chung, Sang-Hyun Ihm, Kwang Il Kim, Eun Joo Cho, Il-Suk Sohn, Sungha Park, Jinho Shin, Sung Kee Ryu, Seok-Min Kang, Myeong-Chan Cho, Ju Han Kim, Jun Hyeok Lee, Jang-Young Kim, Wook Bum Pyun, Ki-Chul Sung
Summary: The study found that blood pressure levels are significantly correlated with the risk of major cardiovascular events (MACE) in Korean patients with hypertension, with no additional benefits observed for MACE among those treated for hypertension with a BP <120/70 mm Hg.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Cardiac & Cardiovascular Systems
Shishir Rao, Milad Nazarzadeh, Dexter Canoy, Yikuan Li, Jing Huang, Mohammad Mamouei, Gholamreza Salimi-Khorshidi, Aletta E. Schutte, Bruce Neal, George Davey Smith, Kazem Rahimi
Summary: This study analyzed health data from 475,442 individuals in the UK aged 60-90 who had at least one prescription of paracetamol. It found that paracetamol formulations containing sodium bicarbonate were associated with increased blood pressure, cardiovascular diseases, and all-cause mortality. However, further analysis showed that this association was primarily due to confounding by indication related to dysphagia and related conditions. Therefore, this study concludes that short-term use of sodium bicarbonate paracetamol in routine clinical practice does not increase the risk of elevated blood pressure and cardiovascular events.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Giacomo Rossitto, Giuseppe Maiolino, Silvia Lerco, Giulio Ceolotto, Gavin Blackburn, Sheon Mary, Giorgia Antonelli, Chiara Berton, Valeria Bisogni, Maurizio Cesari, Teresa Maria Seccia, Livia Lenzini, Alessio Pinato, Augusto Montezano, Rhian M. Touyz, Mark C. Petrie, Ronan Daly, Paul Welsh, Mario Plebani, Gian Paolo Rossi, Christian Delles
Summary: High sodium intake can lead to changes in renal sodium and water handling, increasing glomerular filtration rate, tubular energy expenditure, and promoting protein breakdown. These findings have significant implications for cardiovascular risk in hypertensive patients.
CARDIOVASCULAR RESEARCH
(2021)
Article
Medicine, General & Internal
J. Mesquita Bastos, Lisa Ferraz, Flavio G. Pereira, Susana Lopes
Summary: This study found that ambulatory blood pressure monitoring (ABPM) can predict cardiovascular events in patients with resistant hypertension. The study revealed that 24 h systolic blood pressure, night systolic blood pressure, and 24 h pulse pressure were independent predictors of cardiovascular events. Particularly, patients with a 24 h daytime and nighttime pulse pressure > 60 mm Hg had a higher risk of future cardiovascular events.
Article
Medicine, General & Internal
Chin-Chou Huang, Chia-Min Chung, Chih-Yu Yang, Hsin-Bang Leu, Po-Hsun Huang, Liang-Yu Lin, Tao-Cheng Wu, Shing-Jong Lin, Wen-Harn Pan, Jaw-Wen Chen
Summary: This study found an association between SLC12A3 gene polymorphisms and renal function in patients with hypertension.
FRONTIERS IN MEDICINE
(2022)
Article
Peripheral Vascular Disease
Ryan J. Pewowaruk, Claudia Korcarz, Yacob Tedla, Gregory Burke, Philip Greenland, Colin Wu, Adam D. Gepner
Summary: By analyzing the data from the Multi-Ethnic Study of Atherosclerosis, it was found that load-dependent stiffness was significantly associated with the incidence of cardiovascular disease (CVD) events, while structural stiffness was not.
Article
Peripheral Vascular Disease
Florence Lamarche, Mohsen Agharazii, Francois Madore, Remi Goupil
Summary: This study found that central blood pressure measured with a type I device was statistically but likely not clinically superior to brachial blood pressure in a general population without prior cardiovascular disease. The optimal central systolic blood pressure threshold associated with increased risk of major adverse cardiovascular events was identified as 112 mm Hg.
Article
Cardiac & Cardiovascular Systems
Seong Soon Kwon, Haekyung Lee, Byoung-Won Park, Soon Hyo Kwon, Duk Won Bang, Jin Seok Jeon, Hyunjin Noh, Hyoungnae Kim
Summary: This study evaluated the association between different definitions of glomerular hyperfiltration (GHF) and carotid plaque in a health checkup cohort. The results showed that GHF was positively associated with the presence of carotid plaque, and GHF defined based on creatinine was more sensitive in identifying carotid plaque. Therefore, creatinine-based GHF could serve as a useful surrogate marker for cardiovascular disease surveillance in asymptomatic individuals.
Article
Endocrinology & Metabolism
Bo-Yeon Kim, Ji-In Lee, Hye-Mi Lee, So Hun Kim, Eun Yeong Mo, Jang Won Son, Sihoon Lee, Sungrae Kim
Summary: This study aimed to investigate the optimal blood pressure target in Korean individuals with type 2 diabetes mellitus (T2DM) and analyze its relationship with cardio-renal events and all-cause mortality. The results showed that an SBP of 120-129 mmHg and a DBP of 75-79 mmHg were associated with the lowest risk of all-cause mortality. Lower SBP may be beneficial for patients with T2DM at high risk of renal disease.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Article
Peripheral Vascular Disease
Corey K. Bradley, Eunhee Choi, Marwah Abdalla, Hiroyuki Mizuno, Michael Lam, Maria Cepeda, Dona Sangapalaarachchi, Justin Liu, Paul Muntner, Kazuomi Kario, Anthony J. Viera, Joseph E. Schwartz, Daichi Shimbo
Summary: For most people, high home blood pressure can be identified or ruled out with a high degree of confidence within 3 days or less of monitoring.
Article
Peripheral Vascular Disease
Leo F. Buckley, William L. Baker, Benjamin W. Van Tassell, Jordana B. Cohen, Omar Alkhezi, Adam P. Bress, Dave L. Dixon
Summary: The study found that the amount of time spent within the target range for blood pressure is associated with adverse kidney and cardiovascular events. Better blood pressure control in hypertensive patients is linked to a lower risk of kidney and cardiovascular problems.
Article
Medicine, General & Internal
Sara Mahdavi, Paolo Palatini, Ahmed El-Sohemy
Summary: This study found that the rate of caffeine metabolism is influenced by genetic variation in the CYP1A2 gene, and the association between coffee intake and kidney dysfunction is modified by CYP1A2 genotypes. Among individuals with the AC and CC genotypes, heavy coffee intake is associated with an increased risk of albuminuria, hyperfiltration, and hypertension compared to normal metabolizers.
Article
Peripheral Vascular Disease
Barak Zafrir, Amir Aker, Yosi Asaf, Walid Saliba
Summary: This study investigated the association between blood pressure measurements during exercise stress testing (EST) and the risk of cardiovascular events and the development of hypertension. The results indicated that higher blood pressure levels at rest, submaximal exercise, peak exercise, and recovery were associated with an increased risk of major adverse cardiovascular events (MACE). The association between blood pressure at submaximal exercise and recovery with MACE showed a J-shaped pattern. Among nonhypertensive patients, excessive blood pressure response during peak exercise, as well as submaximal exercise and recovery, were independent predictors of developing hypertension.
JOURNAL OF HYPERTENSION
(2022)
Article
Health Care Sciences & Services
Paivi E. Korhonen, Sem Kiiski, Hannu Kautiainen, Seppo Ojanen, Risto Tertti
Summary: This study investigated the long-term clinical consequences of different eGFR levels calculated by the CKD-EPI equation in apparently healthy cardiovascular risk subjects. It found that subjects with eGFR >= 105 ml/min/1.73 m(2) had an increased risk for all-cause mortality, incident peripheral artery disease, and atrial fibrillation/flutter compared to those with eGFR in the range of 90-104 ml/min. These patients also had a higher mortality rate compared to the general population in Finland. Therefore, close monitoring and timely interventions are necessary for patients with eGFR >= 105 ml/min/1.73 m(2).
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Tatsuya Haze, Nobuhito Hirawa, Yuichiro Yano, Kouichi Tamura, Isao Kurihara, Hiroki Kobayashi, Mika Tsuiki, Takamasa Ichijo, Norio Wada, Takuyuki Katabami, Koichi Yamamoto, Kenji Oki, Nobuya Inagaki, Shintaro Okamura, Tatsuya Kai, Shoichiro Izawa, Masanobu Yamada, Yoshiro Chiba, Akiyo Tanabe, Mitsuhide Naruse
Summary: The study utilized a dataset from a Japanese nationwide registry of patients with primary aldosteronism to determine prognostic factors for cardiovascular diseases. It found that higher aldosterone-to-renin ratio before treatments, higher pulse pressure after treatments, and longer duration of hypertension were associated with increased risk of cardiovascular events. Early intervention may be important for preventing cardiovascular disease among patients with primary aldosteronism.
Article
Sport Sciences
Andrew Haynes, Joanne McVeigh, Leanne Lester, Peter R. Eastwood, Leon Straker, Trevor A. Mori, Lawrence Beilin, Daniel J. Green
Summary: TV watching habits during childhood and adolescence have a negative impact on cardiorespiratory fitness in adulthood, but this impact can be attenuated by engaging in higher levels of physical activity in adulthood.
EUROPEAN JOURNAL OF SPORT SCIENCE
(2023)
Review
Peripheral Vascular Disease
James E. Sharman, Isabella Tan, George S. Stergiou, Carolina Lombardi, Francesca Saladini, Mark Butlin, Raj Padwal, Kei Asayama, Alberto Avolio, Tammy M. Brady, Alan Murray, Gianfranco Parati
Summary: Automated oscillometric blood pressure measuring devices have replaced manual auscultatory blood pressure measurement by mercury sphygmomanometers in clinical settings. These validated devices provide similar blood pressure values to manual measurement, making them the recommended standard for hypertension diagnosis and management globally.
JOURNAL OF HUMAN HYPERTENSION
(2023)
Article
Medicine, General & Internal
Paolo Palatini, Lucio Mos, Francesca Saladini, Olga Vriz, Claudio Fania, Andrea Ermolao, Francesca Battista, Marcello Rattazzi
Summary: The aim of this study was to investigate the reproducibility of white-coat hypertension (WCH) and its predictive capacity for hypertension needing antihypertensive treatment (HT) in young to middle-age subjects. The results showed that WCH has limited reproducibility, and the risk of future hypertension increased when diagnosed with two sets of blood pressure measurements instead of one.
Article
Public, Environmental & Occupational Health
Yiwei Liu, Aya Hirata, Tomonori Okamura, Daisuke Sugiyama, Takumi Hirata, Aya Kadota, Keiko Kondo, Takayoshi Ohkubo, Katsuyuki Miura, Akira Okayama, Hirotsugu Ueshima
Summary: The impact of resting heart rate on cardiovascular disease mortality varies according to serum albumin levels in the general Japanese population.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Multidisciplinary Sciences
Patrick Hilden, Joseph E. Schwartz, Christian Pascual, Keith M. Diaz, Jeff Goldsmith
Summary: This study aims to determine the number of valid observation days needed to obtain reliable measurements of habitual physical activity levels. With a resampling-based approach, the research found that 6 or more valid days are needed for reliable measurements of light physical activity, while 8 and 10 valid days are required for sedentary time and moderate/vigorous activity, respectively.
Review
Medicine, General & Internal
Luca Piscitani, Gianpaolo Reboldi, Angelo Venanzi, Francesca Timio, Annamaria D'Ostilio, Vittorio Sirolli, Mario Bonomini
Summary: Chyloperitoneum is a rare complication of peritoneal dialysis (PD), and it can be caused by trauma or nontrauma, neoplastic disease, autoimmune disease, retroperitoneal fibrosis, or calcium antagonist use. We report six cases of chyloperitoneum in PD patients as a result of using calcium channel blockers. The cloudy peritoneal dialysate cleared up within 24-72 hours after withdrawal of the drug, indicating a potential association between calcium channel blockers and chyloperitoneum. Prompt resolution can be achieved by suspending the offending drug.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Paolo Palatini, Lucio Mos, Francesca Saladini, Olga Vriz, Claudio Fania, Andrea Ermolao, Francesca Battista, Mattia Canevari, Marcello Rattazzi
Summary: The aim of this study was to evaluate the association between alcohol and smoking and cardiovascular and renal events, and to investigate the impact of moderate and heavy alcohol consumption on this association. The findings showed that smoking had a detrimental effect on cardiovascular and renal events in alcohol drinkers, but not in abstainers. There was a synergistic effect between smoking and alcohol use, and this was seen in both moderate and heavy alcohol consumers.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Fabio Angeli, Gianpaolo Reboldi, Francesco Giuseppe Solano, Antonietta Prosciutto, Antonella Paolini, Martina Zappa, Claudia Bartolini, Andrea Santucci, Stefano Coiro, Paolo Verdecchia
Summary: Several outcome-based prospective investigations have shown the prognostic value of 24-hour ambulatory blood pressure monitoring in cardiovascular risk stratification. Average 24-hour, daytime, and nighttime blood pressures are essential components that improve risk assessment beyond traditional factors. However, the interpretation and clinical use of ambulatory blood pressure monitoring need standardization, and implementing its results in individual patient management remains challenging.
Article
Psychology, Multidisciplinary
Kristie M. Harris, Allison E. Gaffey, Joseph E. Schwartz, David S. Krantz, Matthew M. Burg
Summary: This study examined the stability and variability of the Perceived Stress Scale (PSS) using data from two independent samples. The results showed that between-person variance accounted for a large proportion of the total variance in PSS scores, indicating that the PSS may primarily measure a stable perception of stress. However, within-person variance was also observed. These findings suggest that the PSS may have a more stable characteristic in assessing individuals' perception of stress.
ANNALS OF BEHAVIORAL MEDICINE
(2023)
Article
Psychology, Clinical
Corinne Meinhausen, Gabriel J. Sanchez, Donald Edmondson, Ian M. Kronish, Joseph E. Schwartz, Rebecca Hinrichs, Tanja Jovanovic, Jennifer A. Sumner
Summary: This study explores a potential biomarker of PTSD risk, skin conductance (SC) measurement, in a medical trauma population. It found a significant positive association between SC reactivity to recalling the traumatic event and fear-related symptoms of PTSD at 1-month follow-up. These findings suggest that mobile SC reactivity measures may be useful for identifying individuals at risk for fear-related PTSD symptoms following a medical event and shed light on the potential mechanisms involved in their development.
DEPRESSION AND ANXIETY
(2023)
Article
Endocrinology & Metabolism
Ashish Yadav, Lawrence J. Beilin, Rae-Chi Huang, John P. Newnham, Scott W. White, Trevor A. Mori
Summary: This study investigated the relationship between serial ultrasound-derived fetal growth trajectories and markers of insulin resistance in young adults in an Australian pregnancy cohort. The study found that restricted fetal head circumference and abdominal circumference from early pregnancy are associated with higher relative insulin resistance in offspring during adulthood. These findings enhance our understanding of the importance of the intrauterine environment and its impact on the risk of adult diabetes and related metabolic disorders.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2023)
Letter
Cardiac & Cardiovascular Systems
J. Ball, J. T. Neumann, A. M. Tonkin, P. Kirchhof, B. Freedman, A. Brodtmann, C. Reid, M. R. Nelson, L. J. Beilin, S. Fitzgerald, D. Stub, R. L. Woods, J. J. McNeil
EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY
(2023)
Article
Public, Environmental & Occupational Health
Yiwei Liu, Tomonori Okamura, Aya Hirata, Yasunori Sato, Takehito Hayakawa, Aya Kadota, Keiko Kondo, Takayoshi Ohkubo, Katsuyuki Miura, Akira Okayama, Hirotsugu Ueshima
Summary: This study found that smoking is associated with worse quality of life in long-term follow-up.
JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Geriatrics & Gerontology
Sultana Monira Hussain, Andrew M. Tonkin, Gerald F. Watts, Paul Lacaze, Chenglong Yu, Lawrence J. Beilin, Zhen Zhou, Anne B. Newman, Johannes T. Neumann, Cammie Tran, John J. Mcneil
Summary: This study found that higher HDL-C levels are associated with increased risk of cancer and non-cancer non-CVD mortality in healthy older men, but not with CVD mortality. No significant association was found between HDL-C levels and mortality in women.
Article
Geriatrics & Gerontology
A. R. M. Saifuddin Ekram, S. E. Espinoza, M. E. Ernst, J. Ryan, L. Beilin, N. P. Stocks, S. A. Ward, J. J. McNeil, R. C. Shah, R. L. Woods
Summary: This study aimed to examine the association between metabolic syndrome (MetS) and frailty, and determine whether co-existent MetS and frailty affect disability-free survival (DFS). The results showed that MetS was associated with frailty, but MetS alone did not shorten DFS, while frailty increased the risk of reduced DFS.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)