Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques

Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI

(2017) Martina Absinta et al.   eLife

Rates of non-confounded HIV-associated neurocognitive disorders in men initiating combination antiretroviral therapy during primary infection

(2016) Teresa H. Evering et al.   AIDS

Neurologic signs and symptoms frequently manifest in acute HIV infection

(2016) Joanna Hellmuth et al.   NEUROLOGY

Prospective Study of Acute HIV-1 Infection in Adults in East Africa and Thailand

(2016) Merlin L. Robb et al.   NEW ENGLAND JOURNAL OF MEDICINE

SIV Encephalitis Lesions Are Composed of CD163+ Macrophages Present in the Central Nervous System during Early SIV Infection and SIV-Positive Macrophages Recruited Terminally with AIDS

(2015) Brian T. Nowlin et al.   AMERICAN JOURNAL OF PATHOLOGY

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The meningeal lymphatic system: a route for HIV brain migration?

(2015) Susanna L. Lamers et al.   JOURNAL OF NEUROVIROLOGY

The effects of antiretroviral treatment initiation on cognition in HIV-infected individuals with advanced disease in Pune, India

(2015) Manisha Ghate et al.   JOURNAL OF NEUROVIROLOGY

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Compartmentalized Replication of R5 T Cell-Tropic HIV-1 in the Central Nervous System Early in the Course of Infection

(2015) Christa Buckheit Sturdevant et al.   PLoS Pathogens

Giant cell encephalitis and microglial infection with mucosally transmitted simian-human immunodeficiency virus SHIVSF162P3N in rhesus macaques

(2014) Carole Harbison et al.   JOURNAL OF NEUROVIROLOGY

Initiation of ART during Early Acute HIV Infection Preserves Mucosal Th17 Function and Reverses HIV-Related Immune Activation

(2014) Alexandra Schuetz et al.   PLoS Pathogens

Central Nervous System Viral Invasion and Inflammation During Acute HIV Infection

(2012) Victor Valcour et al.   JOURNAL OF INFECTIOUS DISEASES

Recently Infiltrating MAC387+ Monocytes/Macrophages

(2011) Caroline Soulas et al.   AMERICAN JOURNAL OF PATHOLOGY

Loss of mucosal CD4 lymphocytes is an early feature of HIV infection

(2010) S. G. LIM et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Simian Immunodeficiency Virus–Infected Macaques Treated with Highly Active Antiretroviral Therapy Have Reduced Central Nervous System Viral Replication and Inflammation but Persistence of Viral DNA

(2010) M. Christine Zink et al.   JOURNAL OF INFECTIOUS DISEASES

Initiation of HAART during acute simian immunodeficiency virus infection rapidly controls virus replication in the CNS by enhancing immune activity and preserving protective immune responses

(2010) David R. Graham et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

Compartmentalization and Clonal Amplification of HIV-1 Variants in the Cerebrospinal Fluid during Primary Infection

(2009) G. Schnell et al.   JOURNAL OF VIROLOGY

Changes in MRS neuronal markers and T cell phenotypes observed during early HIV infection

(2009) M. R. Lentz et al.   NEUROLOGY

Coordinated Regulation of SIV Replication and Immune Responses in the CNS

(2009) Kenneth W. Witwer et al.   PLoS One

Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques

(2008) William R. Wikoff et al.   JOURNAL OF CLINICAL INVESTIGATION