Hepatitis C Virus core+1/ARF Protein Modulates the Cyclin D1/pRb Pathway and Promotes Carcinogenesis

New liver cancer biomarkers: PI3K/AKT/mTOR pathway members and eukaryotic translation initiation factors

(2017) Nicole Golob-Schwarzl et al.   EUROPEAN JOURNAL OF CANCER

High prevalence of antibodies to core+1/ARF protein in HCV-infected patients with advanced cirrhosis

(2017) Katerina Kassela et al.   JOURNAL OF GENERAL VIROLOGY

The impact of the revolution in hepatitis C treatment on hepatocellular carcinoma

(2016) T. C. Wirth et al.   ANNALS OF ONCOLOGY

Direct-acting antiviral agents for hepatitis C: structural and mechanistic insights

(2016) Matthias Götte et al.   Nature Reviews Gastroenterology & Hepatology

Hepatitis C Virus Frameshift/Alternate Reading Frame Protein Suppresses Interferon Responses Mediated by Pattern Recognition Receptor Retinoic-Acid-Inducible Gene-I

(2016) Seung Bum Park et al.   PLoS One

Chronic hepatitis C virus infection and pathogenesis of hepatocellular carcinoma

(2016) Simonetta Bandiera et al.   Current Opinion in Virology

Hepatitis C Virus–Associated Cancer

(2015) Ming V. Lin et al.   Annual Review of Pathology-Mechanisms of Disease

Recombinant expression of the alternate reading frame protein (ARFP) of hepatitis C virus genotype 4a (HCV-4a) and detection of ARFP and anti-ARFP antibodies in HCV-infected patients

(2015) Michael G. Shehat et al.   ARCHIVES OF VIROLOGY

From non-A, non-B hepatitis to hepatitis C virus cure

(2015) Jean-Michel Pawlotsky et al.   JOURNAL OF HEPATOLOGY

Expression of the Novel Hepatitis C Virus Core+1/ARF Protein in the Context of JFH1-Based Replicons

(2015) Ioly Kotta-Loizou et al.   JOURNAL OF VIROLOGY

Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice

(2015) Thorsten Maass et al.   Oncotarget

Oncogenic viruses and cancer

(2015) Guangxiang George Luo et al.   VIROLOGICA SINICA

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Alternate Reading Frame Protein (F Protein) of Hepatitis C Virus: Paradoxical Effects of Activation and Apoptosis on Human Dendritic Cells Lead to Stimulation of T Cells

(2014) Subodh Kumar Samrat et al.   PLoS One

The flavivirus NS1 protein: Molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker

(2013) David A. Muller et al.   ANTIVIRAL RESEARCH

Both core and F proteins of hepatitis C virus could enhance cell proliferation in transgenic mice

(2013) Wen-Ta Hu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

All-trans retinoic acid induces cellular senescence via upregulation of p16, p21, and p27

(2011) Sun-Hye Park et al.   CANCER LETTERS

High levels of HCV core+1 antibodies in HCV patients with hepatocellular carcinoma

(2011) G. Dalagiorgou et al.   JOURNAL OF GENERAL VIROLOGY

Detection of specific antibodies to HCV-ARF/CORE+1 protein in patients treated with pegylated interferon plus ribavirin

(2011) T. Karamitros et al.   JOURNAL OF VIRAL HEPATITIS

Hepatitis C Virus Infection Causes Cell Cycle Arrest at the Level of Initiation of Mitosis

(2011) R. P. Kannan et al.   JOURNAL OF VIROLOGY

Enhancement of Canonical Wnt/β-Catenin Signaling Activity by HCV Core Protein Promotes Cell Growth of Hepatocellular Carcinoma Cells

(2011) Jiao Liu et al.   PLoS One

An alternative −1/+2 open reading frame exists within viral Npro(1–19) region of bovine viral diarrhea virus SD-1

(2011) Zhen-Chuan Fan et al.   VIRUS RESEARCH

Prevalence of intrinsic disorder in the hepatitis C virus ARFP/Core+1/S protein

(2010) Anissa Boumlic et al.   FEBS Journal

A Short N-Terminal Peptide Motif on Flavivirus Nonstructural Protein NS1 Modulates Cellular Targeting and Immune Recognition

(2010) S. Youn et al.   JOURNAL OF VIROLOGY

Characterization of the Specific CD4+ T Cell Response against the F Protein during Chronic Hepatitis C Virus Infection

(2010) De-Yong Gao et al.   PLoS One

New Insights into Structure and Replication of the Hepatitis C Virus and Clinical Implications

(2010) Marion Poenisch et al.   SEMINARS IN LIVER DISEASE

Oncogenic Potential of Hepatitis C Virus Proteins

(2010) Arup Banerjee et al.   Viruses-Basel

Seroconversion to hepatitis C virus alternate reading frame protein during acute infection

(2009) Yoann Morice et al.   HEPATOLOGY

The HCV ARFP/F/core+1 protein: Production and functional analysis of an unconventional viral product

(2009) Niki Vassilaki et al.   IUBMB LIFE

Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo

(2009) Pippa Newell et al.   JOURNAL OF HEPATOLOGY

Hepatocyte Nuclear Factor 4  Coordinates a Transcription Factor Network Regulating Hepatic Fatty Acid Metabolism

(2009) C. P. Martinez-Jimenez et al.   MOLECULAR AND CELLULAR BIOLOGY

Expression of X-linked inhibitor-of-apoptosis protein in hepatocellular carcinoma promotes metastasis and tumor recurrence

(2008) Ying-Hong Shi et al.   HEPATOLOGY

Differential microRNA expression between hepatitis B and hepatitis C leading disease progression to hepatocellular carcinoma

(2008) Shunsuke Ura et al.   HEPATOLOGY

Hepatitis C Virus NS5A Protein Down-regulates the Expression of Spindle GeneAspmthrough PKR-p38 Signaling Pathway

(2008) Shun-Chi Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatitis C virus ARFP/F protein interacts with cellular MM-1 protein and enhances the gene trans-activation activity of c-Myc

(2008) Hsin-Chieh Ma et al.   JOURNAL OF BIOMEDICAL SCIENCE

Assessment of Specific Antibodies to F Protein in Serum Samples from Chinese Hepatitis C Patients Treated with Interferon plus Ribavarin

(2008) D.-Y. Gao et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Role of the Hepatitis C Virus Core+1 Open Reading Frame and Core cis-Acting RNA Elements in Viral RNA Translation and Replication

(2008) N. Vassilaki et al.   JOURNAL OF VIROLOGY

A reproducible and well-tolerated method for 2/3 partial hepatectomy in mice

(2008) Claudia Mitchell et al.   Nature Protocols