☆ 3.9 Article

Salinity tolerant Aedes aegypti and Ae. albopictus-Infection with dengue virus and contribution to dengue transmission in a coastal peninsula

JOURNAL OF VECTOR BORNE DISEASES (2018)

Journal

JOURNAL OF VECTOR BORNE DISEASES

Volume 55, Issue 1, Pages 26-33

Publisher

WOLTERS KLUWER MEDKNOW PUBLICATIONS

DOI: 10.4103/0972-9062.234623

Keywords

Aedes aegypti; Ae. albopictus; brackish water larval habitats; coastal zones; dengue transmission and rainfall; Jaffna peninsula; salinity tolerant mosquito vectors; Sri Lanka

Funding

University of Jaffna [URG/2016/SEIT/05]
Meteorological Department of Sri Lanka

Ask authors/readers for more resources

Protocol

Community support

Reagent

Community support

Abstract

Background & objectives: Aedes aegypti and Ae. albopictus are major arboviral vectors that are considered to lay eggs, and undergo preimaginal development only in fresh water collections. I Iowever, recently they have been also shown to develop in coastal brackish water habitats. The ability of the biologically variant salinity-tolerant Aedes vectors to transmit arboviral diseases is unknown. We therefore, investigated the infection of salinity-tolerant Aedes mosquitoes with dengue virus (DENV) and analysed dengue incidence and rainfall data to assess the contribution of salinity-tolerant Aedes vectors to dengue transmission in the coastal Jaffna peninsula in Sri Lanka. Methods: Brackish and fresh water developing female Ae. aegypti and Ae. albopictus were tested for their ability to become infected with DENV through in vitro blood feeding and then transmit DENV vertically to their progeny. An immunochromatographic test for the NSI antigen was used to detect DENV Temporal variation in dengue incidence in relation to rainfall was analysed for the peninsula and other parts of Sri Lanka. Results: Aedes aegypti and Ae. albopictus developing in brackish water, became infected with DENV through in vitro blood feeding and the infected mosquitoes were able to vertically transmit DENV to their progeny. Monsoonal rainfall was the discernible factor responsible for the seasonal increase in dengue incidence in the peninsula and elsewhere in Sri Lanka. Interpretation & conclusion: Fresh water Aedes vectors are main contributors to the increased dengue incidence that typically follows monsoons in the Jaffna peninsula and elsewhere in Sri Lanka. It is possible however, that brackish water-developing Aedes constitute a perennial reservoir for DENY to maintain a basal level of dengue transmission in coastal areas of the peninsula during the dry season, and this supports increased transmission when monsoonal rains expand populations of fresh water Aedes.

Authors

I am an author on this paper

Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

3.9

Not enough ratings

Secondary Ratings

Novelty

Significance

Scientific rigor

Rate this paper

Evolution of knockdown resistance (kdr) mutations of Aedes aegypti and Aedes albopictus in Hainan Island and Leizhou Peninsula, China

Minghui Zhao, Xin Ran, Dan Xing, Yun Liao, Wei Liu, Yu Bai, Qiang Zhang, Kan Chen, Lan Liu, Mingyu Wu, Zu Ma, Jian Gao, Hengduan Zhang, Tongyan Zhao

Summary: This study focused on the knockdown resistance (kdr) genes of Aedes aegypti and Aedes albopictus mosquitoes, investigating their mutations and analyzing their haplotype and evolutionary diversity. The results may help identify the evolutionary trend of insecticide resistance and improve the efficiency of biological vector control.

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2023)