Article
Multidisciplinary Sciences
Marcel Prasetyo, Ratna Moniqa, Angela Tulaar, Joedo Prihartono, Stefanus Imanuel Setiawan
Summary: This study aimed to explore the correlation between HEAD-US and HJHS in hemophiliac patients with joint problems in Indonesia. The results showed a moderate correlation between HEAD-US and HJHS scores, indicating that HEAD-US can provide additional value in assessing the joint status in hemophilia patients who received episodic treatment.
Article
Acoustics
Yunmei Fang, Rui Sun, Jingxuan Chang, Cuiming Zhang
Summary: This study assessed the reliability of the HEAD-US-C scale in detecting knee-joint lesions in SHA patients and compared it with MRI. The results showed good inter-rater reliability for the HEAD-US-C scale and excellent agreement between US and MRI for detecting knee lesions in SHA patients. The study suggests that US is important for evaluating knee lesions in SHA patients and may potentially replace MRI.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Haris Majeed, Humayun Ahmed, Marshall S. Sussman, Christopher Macgowan, Tammy Rayner, Ruth Weiss, Brian M. Feldman, Andrea S. Doria
Summary: This study evaluates the value of MRI-T-2 mapping in assessing cartilage status in children with hemophilic arthropathy, finding negative correlations between age and cartilage T-2 relaxation times. The results highlight the potential importance of MRI-T-2 mapping in detecting early cartilage degeneration in children and adolescents with hemophilic arthropathy.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Ana Maria Crespo-Rodriguez, Jesus Sanz Sanz, Dalifer Freites, Zulema Rosales, Lydia Abasolo, Juan Arrazola
Summary: Psoriasis is a common skin disease that can develop into psoriatic arthritis (PsA) in up to 30% of patients, leading to impaired function and reduced quality of life. Early diagnosis and effective treatments are crucial for halting PsA progression. Sensitive imaging techniques such as ultrasound and MRI play an important role in the diagnosis, follow-up, and prognosis of PsA.
INSIGHTS INTO IMAGING
(2021)
Review
Radiology, Nuclear Medicine & Medical Imaging
Claudia Lucia Piccolo, Carlo Augusto Mallio, Federica Vaccarino, Rosario Francesco Grasso, Bruno Beomonte Zobel
Summary: Knee osteoarthritis (KOA) is a common chronic condition that significantly affects the quality of life in the elderly population. Various imaging modalities, including radiography, ultrasound, MRI, CT, and PET-MRI, are available for the diagnosis and evaluation of KOA. Radiography is recommended as the first-line imaging modality due to its availability and clear visualization of bony components, while ultrasound provides information on cartilage thickness and other parameters. MRI is optimal for assessing soft tissue structures, while CT has limited utility. PET-MRI combines morphological and biochemical information but requires further research. Artificial intelligence tools, such as machine learning models, offer potential for improving diagnosis, grading, and predicting the need for surgery in KOA.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Veterinary Sciences
Kayla M. Fowler, Timothy A. Bolton, John H. Rossmeisl, Avril U. Arendse, Karen M. Vernau, Ronald H. L. Li, Rell L. Parker
Summary: This case series provides information on clinical signs, MRI findings, and outcome in 3 juvenile dogs with hemophilia A that developed neurologic deficits or paraspinal hyperesthesia secondary to spontaneous or iatrogenic vertebral canal hemorrhage. Hemophilia A should be considered as a differential in any young dog presenting with an acute onset of hyperesthesia with or without neurologic deficits. This diagnosis should be prioritized in young male dogs that have other evidence of hemorrhage on physical exam.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Orthopedics
Richard F. W. Barnes, Peter Aguero, Cris Hanacek, Andres Flores, Bruno Steiner, Cindy Bailey, Doris V. Quon, Rebecca Kruse-Jarres, Annette von Drygalski
Summary: The JADE protocol is a point-of-care musculoskeletal ultrasound (MSKUS) protocol for evaluating hemophilic arthropathy. It has been found to be consistent with clinical joint health assessments and functional joint evaluations, providing reproducible cross-sectional associations with joint health outcomes.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Orthopedics
N. Gallastegui, Buk Steiner, P. Aguero, C. Bailey, R. Kruse-Jarres, D. Quon, C. Hanacek, L. M. Volland, R. F. W. Barnes, A. von Drygalski
Summary: The study demonstrated that musculoskeletal ultrasound (MSKUS) had a significant impact on physical therapy plans for patients with hemophilic arthropathy, while medical management decisions were less influenced by MSKUS.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mohamed Jarraya, Cheri A. Blauwet, Michel D. Crema, Rafael Heiss, Frank W. Roemer, Daichi Hayashi, Wayne E. Derman, Ali Guermazi
Summary: The study described occurrences of sports-related injuries during the Rio 2016 Summer Paralympic Games using imaging techniques. A total of 109 injuries were reported among 4378 athletes, with bone stress injuries being most common. MRI was the most utilized imaging modality, comprising 63% of imaging examinations. The findings may help in developing future prevention programs for elite para athletes.
EUROPEAN RADIOLOGY
(2021)
Article
Acoustics
Yunmei Fang, Yulin Guo, Ting Qin, Yuting Luan, Cuiming Zhang
Summary: This study aimed to discuss the correlation between the Hemophilia Early Detection Ultrasound in China (HEAD-US-C) score and the Hemophilia Joint Health Score version 2.1 (HJHS 2.1) of the knee joint in patients with hemophilia. The results showed a significant correlation between the ultrasound score and the clinical score, indicating the importance of HEAD-US-C in evaluating hemophilic arthropathy.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Fausto Salaffi, Marina Carotti, Andrea Di Matteo, Luca Ceccarelli, Sonia Farah, Catalina Villota-Eraso, Marco Di Carlo, Andrea Giovagnoni
Summary: This review summarizes the evidence for using ultrasound and MRI to assess sarcopenia and highlights the advantages of ultrasound in evaluating muscle mass, quality, structure, and biomechanical function.
Article
Hematology
Soumya Susan Regi, Roshan S. Livingstone, Madhavi Kandagaddala, Pradeep Poonnoose, Sridhar Gibikote, Shyamkumar N. Keshava, Alok Srivastava
Summary: This study evaluated the sensitivity of ultrasonography and magnetic resonance imaging in detecting small concentrations of blood in joint bleeding. Results showed that the detection of blood using ultrasound depends on variables such as blood concentration, transducer frequency, and imaging timing. As blood concentration decreases, discordance between observers increases.
Article
Radiology, Nuclear Medicine & Medical Imaging
Sevtap Tugce Ulas, Katharina Ziegeler, Sophia-Theresa Richter, Sarah Ohrndorf, Robert Biesen, Fabian Proft, Denis Poddubnyy, Torsten Diekhoff
Summary: This study compared the performance of dual-energy CT and CT subtraction in detecting arthritis, with CT-S having the highest diagnostic accuracy. Both iMap and MRI showed good correlation and interreader reliability. Musculoskeletal ultrasound remains the most available modality for arthritis imaging and served as the gold standard in this study.
EUROPEAN RADIOLOGY
(2022)
Article
Rheumatology
Sevtap Tugce Ulas, Felix Radny, Katharina Ziegeler, Iris Eshed, Juliane Greese, Dominik Deppe, Carsten Stelbrink, Robert Biesen, Hildrun Haibel, Valeria Rios Rodriguez, Judith Rademacher, Mikhail Protopopov, Fabian Proft, Denis Poddubnyy, Torsten Diekhoff
Summary: This study aimed to investigate whether self-reported diagnostic confidence can predict diagnostic accuracy in axial spondyloarthritis imaging. The results showed significant differences in diagnostic confidence between correct and incorrect responses for all imaging modalities, and self-reported diagnostic confidence can serve as useful information to predict diagnostic reliability.
Article
Acoustics
Peter Aguero, Richard F. W. Barnes, Andres Flores, Annette von Drygalski
Summary: This study investigated the feasibility of patient self-imaging with or without teleguidance in persons with hemophilia. The results showed that with teleguidance, all images were acquired correctly with high image quality. The study found that it was easy and fast to navigate and acquire images using mobile technology and teleguidance. This study suggests that mobile ultrasound with teleguidance for joint self-imaging is feasible and should be further explored.
JOURNAL OF ULTRASOUND IN MEDICINE
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Amir Masoud Afsahi, Yajun Ma, Hyungseok Jang, Saeed Jerban, Christine B. Chung, Eric Y. Chang, Jiang Du
Summary: This review article summarizes recent technical developments in ultrashort echo time (UTE) magnetic resonance imaging of musculoskeletal (MSK) tissues with short-T2 relaxation times. It discusses contrast mechanisms for high-contrast morphological imaging of short-T2 MSK tissues and introduces quantitative UTE mapping techniques.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Orthopedics
Saeed Jerban, Takehito Hananouchi, Yajun Ma, Behnam Namiranian, Erik W. Dorthe, Jonathan H. Wong, Niloofar Shojaeiadib, Mei Wu, Jiang Du, Darryl D'Lima, Christine B. Chung, Eric Y. Chang
Summary: The study investigated the correlations between the mechanical and microstructural properties of human ACL specimens and quantitative three-dimensional UTE Cones MRI measures. The results showed significant moderate correlations between UTE-MRI biomarkers and the elastic modulus of ACL, but nonsignificant correlations with histomorphometry measures.
JOURNAL OF ORTHOPAEDIC RESEARCH
(2022)
Article
Biophysics
Lidi Wan, Xin Cheng, Adam C. Searleman, Ya-Jun Ma, Jonathan H. Wong, R. Scott Meyer, Jiang Du, Guangyu Tang, Eric Y. Chang
Summary: The study aimed to investigate the feasibility of quantitative 3D ultrashort echo time (UTE)-based biomarkers in detecting proteoglycan (PG) loss and collagen degradation in human cartilage. The results showed that AdiabT(1 rho) and T-1 have the potential for detecting PG loss, while MMF and MTR are promising for the detection of collagen degradation in articular cartilage, facilitating earlier, noninvasive diagnosis of osteoarthritis.
NMR IN BIOMEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Hyungseok Jang, Jiang Du
Review
Medicine, General & Internal
Keith R. Cole, Karen Goodman, Lena Volland
Summary: The objective of this review is to evaluate and quantify the reporting of dose parameters and dosage for gaze stabilisation exercises, as well as the outcome measures used to assess changes in gaze stabilisation following intervention. The results show that only a small percentage of studies reported all parameters of dose and dosage, and most studies did not use clinical or instrumented measures of gaze stability as outcome measures.
Article
Radiology, Nuclear Medicine & Medical Imaging
Zhao Wei, Alecio F. Lombardi, Roland R. Lee, Mark Wallace, Koichi Masuda, Eric Y. Chang, Jiang Du, Graeme M. Bydder, Wenhui Yang, Ya-Jun Ma
Summary: This study used ultrashort echo time (UTE) scanning technique to evaluate intervertebral discs and found that T-1 rho values are associated with the degree of disc degeneration and age. In addition, there are differences in T-1 rho values between subjects with and without low back pain.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Article
Hematology
Srila Gopal, Richard F. W. Barnes, Lena M. Volland, David Page, Annette von Drygalski
Summary: Objective diagnosis of haemarthrosis by MSKUS facilitates the development of a symptom-based prediction tool for diagnosis of haemarthrosis and could be particularly helpful in situations where MSKUS is not readily available.
Article
Biochemistry & Molecular Biology
Alecio F. Lombardi, Yajun Ma, Hyungseok Jang, Saeed Jerban, Qingbo Tang, Adam C. Searleman, Robert Scott Meyer, Jiang Du, Eric Y. Chang
Summary: This study compared the pH measured in knee joints of individuals without osteoarthritis (OA) and patients with severe OA using acidoCEST-UTE MRI. The results showed that patients with OA had lower pH values in their cartilage, meniscus, and fluid compared to individuals without OA. Moreover, lower pH measurements were associated with worse symptoms and knee-joint function.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Radiology, Nuclear Medicine & Medical Imaging
Saeed Jerban, Salem Alenezi, Amir Masoud Afsahi, Yajun Ma, Jiang Du, Christine B. B. Chung, Eric Y. Y. Chang
Summary: This review article describes the potential of using MRI-based micro-FEA as a non-invasive method to predict bone mechanical competence and assess fracture risk, and discusses its applications and future potential.
MAGNETIC RESONANCE IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hongda Shao, Jiawei Yang, Yajun Ma, Xiaolian Su, Guangyu Tang, Junjie Jiang, Jiang Du, Jianjun Liu
Summary: The study aimed to investigate the diagnostic efficacy of multi-parametric quantitative UTE-based MRI for evaluating human cartilage degeneration. Among the quantitative MRI biomarkers, UTE-MTR had the strongest correlation with OA grade and collagen organization score. UTE-MTR showed the highest diagnostic efficacy for mild cartilage degeneration, while UTE-AdiabT1 rho and CubeQuant-T2 had lower efficacy.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Article
Medicine, General & Internal
Saeed Jerban, Yajun Ma, Amir Masoud Afsahi, Alecio Lombardi, Zhao Wei, Meghan Shen, Mei Wu, Nicole Le, Douglas G. Chang, Christine B. Chung, Jiang Du, Eric Y. Chang
Summary: This study utilized UTE-MT modeling and MRI techniques to detect the correlation between tendon quality deterioration in osteoporosis patients and bone health, highlighting the importance of UTE-MT MRI techniques in evaluating tendon quality.
Article
Orthopedics
N. Gallastegui, Buk Steiner, P. Aguero, C. Bailey, R. Kruse-Jarres, D. Quon, C. Hanacek, L. M. Volland, R. F. W. Barnes, A. von Drygalski
Summary: The study demonstrated that musculoskeletal ultrasound (MSKUS) had a significant impact on physical therapy plans for patients with hemophilic arthropathy, while medical management decisions were less influenced by MSKUS.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Hematology
Duc Q. Tran, Craig C. Benson, Judith A. Boice, Meera Chitlur, Amy L. Dunn, Miguel A. Escobar, Kalpna Gupta, Jill M. Johnsen, James Jorgenson, Scott D. Martin, Suzanne Martin, Shannon L. Meeks, Alfredo A. A. Narvaez Jr, Doris V. Quon, Mark T. Reding, Ulrike M. Reiss, Brittany Savage, Kim Schafer, Bruno Steiner, Courtney Thornburg, Lena M. Volland, Annette von Drygalski
Summary: Decades of research have improved the lives of hemophilia patients. Future research will determine if these developments can truly improve health equity for all hemophilia patients.
EXPERT REVIEW OF HEMATOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mei Wu, Ya-Jun Ma, Mouyuan Liu, Yanping Xue, Lillian Gong, Zhao Wei, Saeed Jerban, Hyungseok Jang, Douglas G. Chang, Eric Y. Chang, Liheng Ma, Jiang Du
Summary: The study evaluated the quantitative assessment of articular cartilage degeneration using 3D UTE-Cones-AdiabT(1 rho) imaging technique. Significant differences in UTE-Cones-AdiabT(1 rho) values were observed among different extents and depths of cartilage lesions, indicating its potential for early diagnosis of cartilage degeneration.
EUROPEAN RADIOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Takehito Hananouchi, Tomoyuki Suzuki, Erik W. Dorthe, Jiang Du, Darryl D. D'Lima
Summary: Using a probing device, the resistance force of dissected ACLs was measured, and its correlation with the mechanical properties of the ligaments was investigated. The results showed a moderate correlation, suggesting that the tension of the reconstructed ACL after fixation can be derived from the value of the probing device.
BIOENGINEERING-BASEL
(2022)