Article
Environmental Sciences
Sofi Jonsson, Michelle Nerentorp Mastromonaco, Feiyue Wang, Andrea G. Bravo, Warren R. L. Cairns, John Chetelat, Thomas A. Douglas, Gretchen Lescord, Liisa Ukonmaanaho, Lars-Eric Heimburger-Boavida
Summary: Anthropogenic mercury undergoes long-range transport to the Arctic and can be transformed into methylmercury, potentially leading to high exposure in Arctic inhabitants and wildlife. Biogeochemical and ecological processes in the Arctic play a crucial role in determining the environmental exposure of mercury, particularly the bioavailability, methylation and demethylation, bioaccumulation, and biomagnification of methylmercury. Recent scientific advances have provided insights into these processes and highlighted their importance in understanding the fate of anthropogenic mercury in Arctic ecosystems.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Thais de Castro Paiva, Eurizangela Pereira Dary, Inacio Abreu Pestana, Sidineia Aparecida Amadio, Olaf Malm, Daniele Kasper
Summary: This study finds that the bioaccumulation of mercury in fishes from an Amazonian lake is influenced by biological characteristics and environmental changes. Feeding habits and seasonal flood-pulse have a significant impact on mercury concentrations in fish muscles.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Gabriela Echevarria, Nathan K. Lujan, Jose Montoya, Maria Genoveva Granda-Albuja, Jonathan Valdiviezo-Rivera, Fernando Sanchez, Francisco Cuesta, Blanca Rios-Touma
Summary: The escalating industrial and artisanal extraction of natural resources in the Amazon Basin has raised global environmental concerns. This study focuses on the problems of heavy metals pollution and biomagnification, which result from various activities such as mining and industrial discharges. By analyzing fish specimens and conducting stable isotope analyses, the study reveals elevated concentrations of certain heavy metals, particularly aluminum, arsenic, and mercury, in fish species that pose significant risks to human consumers. The study also highlights concerning trends, including increasing metal concentrations and mercury biomagnification within fish populations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Zhong-Li Huang, Zhan-Biao Yang, Xiao-Xun Xu, Yong-Jia Lei, Jin-Song He, Song Yang, Ming Hung Wong, Yu-Bon Man, Zhang Cheng
Summary: This study investigated the bioaccumulation of total and methylmercury by housefly maggots during the conversion of food waste, and assessed the human health risk of mercury through fish consumption. The results showed that maggots fed with vegetable and meat waste had higher methylmercury concentrations compared to other waste feed ratios. The mercury concentrations in tilapia fed with the converted maggots were within safe levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Sonia Romero-Romero, Efren Garcia-Ordiales, Nieves Roqueni, Jose Luis Acuna
Summary: Despite their remote location, deep-sea species have the ability to accumulate mercury, mainly in the form of the neurotoxin methylmercury (MeHg). The concentration of MeHg increases with the depth of occurrence of fish, and is influenced by their habitat. MeHg can be used as an indicator of a species' trophic position in the food web.
Review
Environmental Sciences
Beatriz Malcata Martins, Nelson J. O'Driscoll, Mark L. Mallory, Joao Canario
Summary: This review examines bioaccumulation of MeHg in freshwater invertebrates, particularly insects, highlighting the lack of robust environmental data in many studies. Providing physical and chemical characteristics of study sites is important for examining MeHg bioaccumulation and biomagnification, which will improve future mercury risk assessment analyses.
BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
(2021)
Article
Environmental Sciences
Adi Barocas, Claudia Vega, Alejandro Alarcon Pardo, Julio M. Araujo Flores, Luis Fernandez, Jessica Groenendijk, Jessica Pisconte, David W. Macdonald, Ronald R. Swaisgood
Summary: Driven by global gold price surges and additional socio-economic factors, artisanal small-scale gold mining (ASGM) in the Global South is increasing, resulting in significant mercury (Hg) emissions into the air and fresh-water. This study examined the factors influencing mercury accumulation in fish in oxbow lakes in Peru's Madre de Dios region and found that Hg levels were associated with ASGM activities, water quality, and fish trophic level. The results highlight the risks of high Hg exposure to human and top carnivore populations in neotropical ecosystems undergoing degradation due to ASGM.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Qiang Wang, Xingchun Li, Xuehong Zhou
Summary: Understanding trophic magnification factors (TMFs) is important for environmental management. Trophic position (TP) is a key parameter in TMFs assessment and can be estimated using nitrogen stable isotopes (δN-15). However, there are limitations in determining the ΔN-15 between trophic positions and selecting baseline species, which introduce uncertainty into TP and TMFs assessment. This study compared two frameworks (additive ΔN-15 and scaled ΔN-15) of the food chain in two interconnected freshwater ecosystems for the first time and found that TMFs differed significantly between the two lakes under the scaled framework but not under the additive framework. Based on these findings, we recommend using the scaled ΔN-15 framework for future TMFs assessments to improve the accuracy of TP assessment.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Gustavo Chiang, Karen A. Kidd, Mauricio Diaz-Jaramillo, Winfred Espejo, Paulina Bahamonde, Nelson J. O'Driscoll, Kelly R. Munkittrick
Summary: This study found that both the composition of the food web and the proximity to freshwater outflows are key factors influencing the trophic magnification slopes for methylmercury in Patagonian and Antarctic food webs.
Article
Environmental Sciences
Xiaoyu Xu, Albert L. Bryan, Jasmine R. Parks, Kara N. Gibson
Summary: This study investigated the deposition and accumulation of mercury in a stream ecosystem. The results showed a correlation between labile mercury in porewater and bioaccumulative mercury in biota. The study found that surface sediment had higher mercury concentrations, and most of the sediment mercury existed in non-labile forms. Additionally, sulfate levels influenced mercury methylation and methyl-mercury production in the sediment. Methyl-mercury concentrations in the aquatic food web increased with trophic levels.
Article
Ecology
Edd Hammill, Maya Pendleton, Janice Brahney, Karin M. Kettenring, Trisha B. Atwood
Summary: Wetland plants tolerate hazardous metals through exclusion or accumulation. Metal sequestration in Great Salt Lake wetlands was evaluated for both invasive and native plant species, as well as terrestrial invertebrates. Arsenic and copper concentrations were higher in plant tissues, while lead concentrations were higher in the invasive plant. All plants excluded arsenic and selenium, storing most of the metals in belowground tissues. Lead, copper, and cadmium were transferred to aboveground tissues, facilitating their movement into invertebrates, particularly predators.
Article
Engineering, Environmental
Peipei Wu, Yanxu Zhang
Summary: This study combines a fish ecological model and an ocean methylmercury model to explore the factors and mechanisms of methylmercury transfer in marine fish food webs. The results show that the available methylmercury in zooplankton strongly affects the methylmercury content in fish, and medium-sized fish are critical intermediaries in transferring methylmercury in the food webs. Feeding interactions influenced by ecosystem structures determine the degree of methylmercury biomagnification. It is estimated that the global population potentially consumes 6.1 metric tons of methylmercury per year through marine fish consumption. This model provides a useful tool for quantifying human exposure to methylmercury through marine fish consumption and fills a critical gap in the effectiveness evaluation of the convention.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Environmental
Peipei Wu, Yanxu Zhang
Summary: This study explores the influencing factors and mechanisms of methylmercury (MMHg) transfer in marine fish food webs using a fish ecological model and an ocean methylmercury model. The results show that available MMHg in the zooplankton strongly determines MMHg levels in fish. Medium-sized fish play a critical role in transferring over 70% of the circulating MMHg in food webs. Grazing and feeding interactions influenced by ecosystem structures determine the biomagnification of MMHg. Globally, the population potentially digests 6.1 metric tons of MMHg per year through marine fish consumption. This model provides a useful tool for quantifying human exposure to MMHg and evaluating the effectiveness of the Minamata Convention.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
Melissa A. McKinney, John Chetelat, Samantha M. Burke, Kyle H. Elliott, Kim J. Fernie, Magali Houde, Kimmo K. Kahilainen, Robert J. Letcher, Adam D. Morris, Derek C. G. Muir, Heli Routti, David J. Yurkowski
Summary: Global climate change has had a significant impact on the Arctic environment and ecosystems, affecting mercury (Hg) levels in Arctic biota. The marine environment has higher Hg levels compared to terrestrial environments, leading to changes in Hg concentrations in herbivores and predators in the Arctic region.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Geosciences, Multidisciplinary
Devanita Ghosh, Anwesha Ghosh, Punyasloke Bhadury
Summary: This review discusses the occurrence of arsenic (As) in various aquatic habitats and the direct or indirect effects on different organisms, including bacteria, algae, phytoplankton, zooplankton, and higher trophic levels. Special emphasis is given to finfishes and shellfishes that are commonly consumed by humans. The review also provides an overview of commonly used detection methods for As and highlights the importance of using As metabolites as an indicator of human exposure. Furthermore, the integration of 'omics' approaches and advanced sequencing technologies is emphasized for global monitoring of the human gut microbiome and understanding the effects and consequences of As bioaccumulation.
GEOSCIENCE LETTERS
(2022)
Article
Environmental Sciences
Gabriel Oliveira de Carvalho, Rodrigo Ornellas Meire, Adan Santos Lino, Debora Regina Yogui, Arnaud Leonard Jean Desbiez, Joao Paulo Machado Torres, Olaf Malm
Summary: This study investigated the mercury (Hg) levels in the fur of giant anteaters in the state of Mato Grosso do Sul, Brazil. The study found that juveniles had lower Hg concentrations than adults, and that the stage of carcass decomposition and vehicular traffic volume did not influence Hg levels. A spatial pattern of higher Hg concentrations in the eastern-southeastern region of the state was identified, potentially due to anthropogenic impacts.
Article
Environmental Sciences
B. M. R. Manhaes, E. B. Santos-Neto, L. R. Tovar, E. B. Guari, L. Flach, D. Kasper, P. M. A. Galvao, O. Malm, R. A. Goncalves, T. L. Bisi, A. F. Azevedo, J. Lailson-Brito
Summary: An unusual mortality event attributed to morbillivirus infection affected total mercury, methylmercury, and selenium bioaccumulation and body burden in Guiana dolphins. Differences in Se concentrations were found in individuals collected during the UME, likely due to impairment of the detoxification process in the liver. THg concentrations in the liver were higher and differed among organs, while Se concentrations in the skin and kidney were higher and varied among other tissues/organs.
Article
Environmental Sciences
Claudio E. T. Parente, Evelyn Oliveira da Silva, Sidney Fernandes Sales Junior, Rachel Ann Hauser-Davis, Olaf Malm, Fabio Verissimo Correia, Enrico Mendes Saggioro
Summary: The study revealed significant effects of contaminated poultry litter on earthworms, including avoidance, biomass loss, lethality, reproductive impacts, and changes to immune cells. Investigations showed that poultry litter strongly repels earthworms even at the lowest concentration.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Yago Guida, Raquel Capella, Natsuko Kajiwara, Joshua Olajiire Babayemi, Joao Paulo Machado Torres, Roland Weber
Summary: Despite their adverse impacts, global demand for chlorinated paraffins continues to rise. Short-chain chlorinated paraffins have been listed as persistent organic pollutants, yet exemptions have been granted for their applications. Brazil has developed its first SCCP inventory, assessed the feasibility of guidance, and provided technical insights into SCCPs.
Review
Environmental Sciences
Patricia C. G. Pereira, Claudio E. T. Parente, Gabriel O. Carvalho, Joao P. M. Torres, Rodrigo O. Meire, Paulo R. Dorneles, Olaf Malm
Summary: Flower import regulations are restricted for food security and biosafety, but the lack of pesticide limits for ornamental flowers can result in overuse of pesticides and trade of contaminated products. Many countries ban certain pesticides in flower production, with more research in developed countries, but there are still risks to both the environment and human health.
ENVIRONMENTAL POLLUTION
(2021)
Article
Environmental Sciences
Sidney Fernandes Sales Junior, Evelyn Oliveira da Silva, Gabriel de Farias Araujo, Lorena Oliveira Souza Soares, Claudio Ernesto Taveira Parente, Olaf Malm, Enrico Mendes Saggioro, Fabio Verissimo Correia
Summary: Long-term exposure of Eisenia andrei earthworms to fluoroquinolone-contaminated poultry litter led to increased CAT and SOD activities, as well as dose-dependent responses in GST and GSH levels. However, lipid peroxidation levels showed a decreasing trend. These findings suggest a trend of antioxidant system attenuation in response to successive poultry litter applications, with major alterations observed in the first month of exposure.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Environmental Sciences
Leandro de Oliveira Drummond, Rodrigo Ornellas Meire, Caryne Braga, Carlos Eduardo de Rezende, Olaf Malm, Rui Cerqueira
Summary: This study investigated the influence of altitudinal distribution, size, trophic position, and degree of water dependence on mercury concentration in amphibians in a mountainous complex in southeastern Brazil. The results showed a positive relationship between elevation and mercury concentration in topsoil samples from rainforest sites, while samples from cloud forest and highland grasslands had lower mercury concentration than expected. This suggests that vegetation structure plays a key role in the deposition of atmospheric mercury, and various factors such as elevation, trophic level, and water dependence affect mercury concentration in amphibians.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Fabio Barbosa Machado Torres, Yago Guida, Roland Weber, Joao Paulo Machado Torres
Summary: The article discusses the status of PFAS in Brazil, including its classification as persistent organic pollutants, import and export data, and domestic trade data. The study finds that although listed PFAS are present in Brazil, there is a lack of research on the topic, indicating a need for strategies to increase stakeholder engagement and reinforce control over PFAS trade.
Article
Environmental Sciences
Jose E. Celis, Winfred Espejo, Janeide de A. Padilha, Karen A. Kidd, Rodrigo Goncalves, Paulo Dorneles, Douglas Oliveira, Olaf Malm, Christopher A. Celis, Gustavo Chiang
Summary: Trace metals bioaccumulate and some biomagnify in aquatic organisms, posing a threat to organisms and human consumers. This study investigated the trophodynamics of trace metals in aquatic food webs from remote coastal zones in the southern hemisphere, revealing the influence of geographic location and species on the fate of these metals.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
G. P. Bighetti, J. A. Padilha, L. S. T. Cunha, O. Malm, P. L. Mancini
Summary: Seabird feathers are important matrices for analyzing environmental contaminants. In this study on brown boobies, the concentration of total mercury (THg) was measured in different types of feathers, revealing higher levels in ventral and wing feathers compared to dorsal and tail feathers. Juvenile birds had lower concentrations of THg in all feather types compared to adults. Ventral feathers are suggested as the most suitable biomonitor for THg contamination in brown boobies, but further studies are needed for other tropical seabird species.
Article
Environmental Sciences
Gabriela Cugler de Pontes, Murilo de Carvalho Vicente, Daniele Kasper, Wilson Thadeu Machado, Julio Cesar Wasserman
Summary: The main goal of this study was to evaluate the distributions of total mercury (THg) and methylmercury (MeHg) concentrations in the sediments of Jurujuba Cove and their associations with physical and chemical parameters, assessing their geochemical behavior. The results showed that grain size acted as the main diluting agent. The highest THg concentrations were observed in the mussel-farm area, related to fine grain size and elevated organic carbon values.
Article
Environmental Sciences
Christiane N. Monte, Ana Paula C. Rodrigues, Petrus M. A. Galvao, Gabriela C. Pontes, Olaf Malm, Julio C. Wasserman, Wilson Machado
Summary: This study evaluates the behavior of mercury and its methylmercury (MeHg) response upon sediment resuspension in two impacted areas of Guanabara Bay. The results show a statistically significant correlation between MeHg and resuspension time in the Rio de Janeiro Harbor sediments, indicating net methylation. This highlights the importance of considering concentration changes due to sediment resuspension-redeposition processes when assessing the variability of MeHg and associated toxicity risks.
ENVIRONMENTAL MONITORING AND ASSESSMENT
(2022)
Article
Environmental Sciences
Yago Guida, Hidenori Matsukami, Natsuko Kajiwara
Summary: CPs, including SCCPs and MCCPs, are widely used hazardous chemical additives in PVC. This study assessed the occurrence of SCCPs and MCCPs in PVC consumer goods in the Japanese market, and found that most impacted products were manufactured overseas.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Environmental Sciences
Thais de Castro Paiva, Eurizangela Pereira Dary, Inacio Abreu Pestana, Sidineia Aparecida Amadio, Olaf Malm, Daniele Kasper
Summary: This study finds that the bioaccumulation of mercury in fishes from an Amazonian lake is influenced by biological characteristics and environmental changes. Feeding habits and seasonal flood-pulse have a significant impact on mercury concentrations in fish muscles.
ENVIRONMENTAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Sadia Anjum, Hamile Ali, Faiza Naseer, Maisa S. Abduh, Halima Qadir, Salik Kakar, Yasir Waheed, Tahir Ahmad
Summary: This study demonstrates that avocado and papaya fruit juices can reduce the accumulation of cadmium in the liver, kidney, and hippocampal tissues, and upregulate the expression of antioxidant enzymes while reducing lipid peroxidation. Compared to avocado, papaya has a stronger potential for improving memory and learning, as well as reducing lipid peroxidation in various tissues.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Celio Junior da C. Fernandes, Gerson Santos de Almeida, Patricia Fretes Wood, Anderson M. Gomes, Fabio J. Bezerra, Jose C. S. Vieira, Pedro M. Padilha, Willian F. Zambuzzi
Summary: This study demonstrates the role of mechanosignaling in the promotion of an osteoblastic phenotype in response to zirconia exposure. The release of angiocrine factors modulated by mechanosignaling is crucial in creating a microenvironment that promotes wound healing and osseointegration. These findings highlight the importance of considering endothelial cell mechanosignaling in bone healing and osseointegration in the context of blood vessel effects.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Rehab I. Abdel-Karim, Rania K. Hashish, Dahlia I. Badran, Sally S. Mohammed, Noha A. Salem
Summary: The study found that chlorpyrifos has hepatotoxicity, while cerium oxide nanoparticles can alleviate this toxicity. Cerium oxide nanoparticles can protect the liver by reducing the expression of inflammatory and apoptotic proteins and increasing the activity of antioxidant enzymes.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Tahani El Ayari, Raja Ben Ahmed, Zaineb Hammemi, Abdessalem Kouki, Emna Chelb, Salwa Nechi, Najoua Trigui El Menif
Summary: This study assessed the effects of samarium doped zinc oxide nanoparticles (Sm doped ZnO NPs) on the edible mussel Mytilus galloprovincialis and found that it led to a decrease in filtration rates and histopathological alterations in the gills, digestive glands, and gonads.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Shanshan Niu, Zhangmin Wang, Xuebin Yin, Xiaodong Liu, Liqiang Qin, Muhammad Raza Farooq, Ofori Prince Danso, Zezhou Zhang, Qin Luo, Chenlu Sun, Jiaping Song
Summary: This study investigated the transport of selenium through the soil-crop-human chain in regions with different selenium levels. It found that the residents' dietary selenium intake was related to the selenium content in soil, with one village within the WHO recommended intake range while the other village was at risk of selenium deficiency. There were significant positive correlations between residents' dietary selenium intake and the three selenium biomarkers.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Sanaz Salaramoli, Hamid Reza Joshaghani, Ali Shoeibi, Seyed Isaac Hashemy
Summary: The study suggests that serum levels of selenium and selenoprotein P may serve as biomarkers or risk factors for Parkinson's disease. Additionally, there is a correlation between alpha-synuclein levels and disease stage. Further research is needed to understand the role of selenoprotein S in reducing alpha-synuclein aggregation.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Motozumi Ando, Keiko Suzuki, Riko Kitamoto, Ayako Nakayama, Norio Watanabe, Masami Kawahara
Summary: C57BL/6 mice and BALB/c mice showed different expression profiles of selenoprotein P after a high-fat diet (HFD). C57BL/6 mice in the HFD group had higher body weight, fasting plasma glucose levels, and plasma selenoprotein P levels compared to the ND group. However, BALB/c mice did not show significant differences in fasting plasma selenoprotein P levels between the HFD and ND groups.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Ruihan Song, Huanhuan Chen, Runqing Zhan, Miaomiao Han, Longzhu Zhao, Xiaoli Shen
Summary: This study aims to investigate the protective effects of Vitamin E (Vit E) on manganese (Mn)-induced nigrostriatal system lesions. The results demonstrate that Vit E improves behavioral disorders, attenuates the loss of nigral dopaminergic neurons, and restores mitochondrial function. Additionally, the protective effect of Vit E may be associated with the upregulation of CHRM1 and KCNJ4 mRNA.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Jose Luan da Paixao Teixeira, Ana Paula Rebellato, Maria Isabel Andrekowisk Fioravanti, Raquel Fernanda Milani, Marcelo Antonio Morgano
Summary: The study aimed to determine the total Se content and bioaccessibility in commercial plant-based beverages, with results showing that only one beverage made from organic cashew nuts could meet the recommended Se intake for different populations. High bioacessibility percentages were observed in the beverages.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Andreas F. Lehner, Sarah Rebolloso, Paul P. Calle, Karen Ingerman, Gregory A. Lewbart, Juan Pablo Munoz-Perez, Carlos A. Valle, John P. Buchweitz
Summary: The dried blood spot (DBS) technology is useful for storing blood samples from wildlife, and this study developed methods for measuring several important elements in DBS and used them for health assessments of Galapagos land iguanas. The results showed that the DBS samples accurately reflected the concentrations of various elements compared to plasma samples, with some divergences observed between different species.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Shuang Zhou, Chunbei Zhou, Jun Xie, Fei Luo, Ning Yao
Summary: The study illustrates the changes in iodized salt usage, goiter rate, and median urinary iodine concentration in school-aged children in Chongqing over the past 21 years. Adequate iodized salt consumption can eliminate iodine deficiency disorders in children, but excessive iodine intake from salt can lead to high urinary iodine excretion and even goiter. Continuous monitoring and adjustment of iodine fortification levels in household table salt is crucial.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Agustin B. Actis Dato, Valeria R. Martinez, Jorge O. Velez Rueda, Enrique L. Portiansky, Veronica De Giustu, Evelina G. Ferrer, Patricia A. M. Williams
Summary: The zinc coordination complex ZnMD, synthesized in this study, showed promising effects in treating hypertension and cardiac hypertrophy. It was more effective than the antihypertensive drug MD in reducing blood pressure and preventing myocardial hypertrophy. ZnMD also exhibited protective effects on the heart by reducing oxidative damage and regulating the expression of oxidative enzymes. These findings suggest that ZnMD has the potential to be developed as a therapeutic drug for hypertension and cardiac dysfunction.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mina Sarani, Maryam Roostaee, Mahboubeh Adeli-Sardou, Davood Kalantar-Neyestanaki, Seyed Amin Ayatollahi Mousavi, Azam Amanizadeh, Mahmood Barani, Alireza Amirbeigi
Summary: This study successfully synthesized nano bismuth oxide using green synthesis methods. The nano particles doped with silver and copper demonstrated excellent antibacterial properties and selective cytotoxicity against cancer cells. These findings have important implications for biomedical and therapeutic applications.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mona Abdel-Rahman, Heba M. Elmasry, Omar A. Ahmed-Farid, Sherein M. Hegazy, Mohamed M. Rezk
Summary: This study investigates the neuro effects of lanthanides on different brain areas in rats and finds that they can distribute and accumulate in various brain regions. Treatment with cerium nanoparticles or lanthanum causes a significant decrease in norepinephrine, dopamine, serotonin, and GABA, accompanied by a significant increase in 5-hydroxyl indoleacetic acid levels. Moreover, cerium nanoparticles exhibit high activity in scavenging free radicals.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
Article
Biochemistry & Molecular Biology
Mahshid Deldar Abad Paskeh, Nahid Babaei, Mehrdad Hashemi, Abbas Doosti, Kiavash Hushmandi, Maliheh Entezari, Saeed Samarghandian
Summary: The combination of curcumin, vitamins D and E with Fe2O3-NPs and MnO2-NPs has shown to improve semen parameters and reduce apoptosis in germ cells in rats with testicular hyperthermia. This study suggests that this combination therapy may have a positive effect on fertility and decreasing the toxic effects of nanoparticles.
JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
(2024)
