The Roles Of Academia, Rare Diseases, And Repurposing In The Development Of The Most Transformative Drugs

WIPO Re:Search: Catalyzing Collaborations to Accelerate Product Development for Diseases of Poverty

(2014) Roopa Ramamoorthi et al.   CHEMICAL REVIEWS

Where do new medicines originate from in the EU?

(2014) Helene Lincker et al.   NATURE REVIEWS DRUG DISCOVERY

Defining “Innovativeness” in Drug Development: A Systematic Review

(2013) A S Kesselheim et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The most transformative drugs of the past 25 years: a survey of physicians

(2013) Aaron S. Kesselheim et al.   NATURE REVIEWS DRUG DISCOVERY

A Brief History of Anti-VEGF for the Treatment of Ocular Angiogenesis

(2012) Leo A. Kim et al.   AMERICAN JOURNAL OF PATHOLOGY

NCATS launches drug repurposing program

(2012) Malorye Allison   NATURE BIOTECHNOLOGY

A decade of change

(2012) John Arrowsmith   NATURE REVIEWS DRUG DISCOVERY

The evolving experience with therapeutic TNF inhibition in sepsis: considering the potential influence of risk of death

(2011) Ping Qiu et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Characteristics of Clinical Trials to Support Approval of Orphan vs Nonorphan Drugs for Cancer

(2011) Aaron S. Kesselheim   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The productivity crisis in pharmaceutical R&D

(2011) Fabio Pammolli et al.   NATURE REVIEWS DRUG DISCOVERY

The Role of Public-Sector Research in the Discovery of Drugs and Vaccines

(2011) Ashley J. Stevens et al.   NEW ENGLAND JOURNAL OF MEDICINE

Emergence of orphan drugs in the United States: a quantitative assessment of the first 25 years

(2010) M. Miles Braun et al.   NATURE REVIEWS DRUG DISCOVERY