Article
Chemistry, Multidisciplinary
Alina Gabriela Rusu, Aurica P. Chiriac, Loredana Elena Nita, Vera Balan, Alexandru Mihail Serban, Alexandra Croitoriu
Summary: This study aims to determine the possibility of substituting GA with SA as a crosslinking agent in the process of enzyme immobilization. A comparison between SA- and GA-functionalized magnetic nanoparticles was conducted, and the results showed that the SA-functionalized MNPs had better stability and catalytic performance compared to the GA-modified MNPs. Therefore, they have greater potential as catalytic nanodevices for biomedical purposes.
Article
Chemistry, Analytical
Tianhua Xie, Di Xu, Yunsheng Shang, Yunpeng Li, Yingqiu Gu, Guohai Yang, Lulu Qu
Summary: Detection of tumor markers is crucial for early diagnosis and improved survival rate in cancer patients. However, developing a highly sensitive and selective method to detect the tumor marker IL-6 in primary liver cancer is challenging due to limited IL-6 concentration and various interfering substances. In this study, a magnetic SERS immunoassay based on R-Fe3O4 was developed, which demonstrated excellent detection capability and selectivity for IL-6. The ultra-sensitivity and high selectivity of this method hold great prospects for medical detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Food Science & Technology
Yao Yu, Yansong Li, Qi Zhang, Yonghong Zha, Shiying Lu, Yong Yang, Peiwu Li, Yu Zhou
Summary: A colorimetric immunoassay based on the aggregation of gold nanoparticles was proposed for the detection of FB1, with a low detection limit, no cross-reaction with other mycotoxins, and potential application for food safety monitoring.
Article
Chemistry, Analytical
Jutao Hu, Xiaoyu Su, Lei Yuan, Kaiyi Zheng, Xiaobo Zou, Zongbao Sun, Xuechao Xu, Wen Zhang
Summary: Accurate and sensitive detection of chloramphenicol (CAP) in natural samples is achieved using an enzyme-regulated fluorescence sensor. A Fe3O4@COF/Fe3+ probe is developed, where Fe3O4@COF acts as a magnetic carrier and signal probe. The sensor demonstrates good stability, reusability, and a logarithmic linear relationship between CAP concentration and fluorescence intensity, providing a reliable method for CAP detection with a low limit of detection.
ANALYTICA CHIMICA ACTA
(2023)
Article
Engineering, Environmental
Yu Zhang, Mingfu Gong, Xiang Li, Hongyu Liu, Penghui Liang, Shuhua Cui, Liang Zhang, Chunyu Zhou, Tao Sun, Maosheng Zhang, Cong-Ying Wen, Jingbin Zeng
Summary: In this study, an ultrasensitive colorimetry for Salmonella typhimurium detection was developed using multifunctional Au-Fe3O4 dumbbell-like nanoparticles (DBNPs), which showed excellent detection capability, efficient capture capability, and good stability and specificity.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Applied
Wei Huang, Luyu Wei, Rongbin Nie, Xiaohan Li, Peng Lu, Yiping Chen
Summary: An integrated strategy for the rapid and sensitive detection of deoxynivalenol in cereals was developed by combining Fe3O4 magnetic nanoparticle-modified metal organic framework-5-based magnetic solid-phase extraction and the optical fiber-based homogeneous chemiluminescence immunosensor. The hybrid magnetic material exhibited good enrichment capacity up to 1.68 mg/g. The competitive immunoassay-based homogeneous chemiluminescence immunosensor enabled washing-free and high-sensitivity detection of deoxynivalenol.
Article
Chemistry, Analytical
Zihui Liang, Yixin Nie, Xin Zhang, Peilin Wang, Qiang Ma
Summary: A novel multiplex electrochemiluminescence polarization assay was developed to detect breast cancer-related genes BRCA1 and BRCA2 simultaneously. The study revealed the relation between the structure of metal nanomaterials and SPC-ECL, and a high polarization-resolved sensing system was designed to detect multitarget DNA. Polarization-based multiple ECL analysis has broad prospects in related cancer diagnosis and treatment evaluation.
ANALYTICAL CHEMISTRY
(2021)
Article
Food Science & Technology
Zixin Zhu, Qiuyun Shi, Jianwei Wu, Kangli He, Jianguo Feng, Sa Dong
Summary: Acetamiprid (ACE) is a widely used chemical in vegetables to control pests, but its residues pose a threat to human health. To rapidly detect ACE residues in vegetables, researchers have developed an indirect competitive chemiluminescence enzyme immunoassay (ic-CLEIA), which is simple, sensitive, and accurate.
Article
Optics
Naheda H. A-Jarah, Ahmed S. Wasfi, S. M. Hamidi
Summary: This study aims to control the performance of random lasers by using magneto-plasmonic Fe3O4@Au and Au@Fe3O4 core shell nanoparticles as scatterer points. The results show that the laser efficiency of the samples is improved when an external magnetic field is applied.
OPTICS AND LASER TECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Rui Yang, Chuanbao Yuan, Wenxuan Dong, Yueran Ren, Yangyang Xue, Hua Cui
Summary: In this study, magnetic nanoparticles with excellent catalytic performance and fast magnetic separation ability were synthesized and used for constructing a label-free chemiluminescence immunosensor for antioxidant detection. The developed immunosensor exhibited a wide linear range and low detection limit, making it suitable for clinical diagnosis.
ACS APPLIED NANO MATERIALS
(2022)
Article
Biochemistry & Molecular Biology
Yina Cai, Binxue Ren, Chifang Peng, Cunzheng Zhang, Xinlin Wei
Summary: New nanocomposites, Fe3O4@Au-FITC, have been prepared and explored for the fluorescent detection of Pb2+. The method has shown a detection limit of 5.2 nmol/L and a linear range of 0.02-2.0 mu mol/L for Pb2+, with minimal response to common metal ions, and demonstrated successful detection of Pb2+ spiked in a lake-water sample with recoveries of 98.2-106.4%. Through ion-induced nanomaterial etching, this method shows great potential for developing robust fluorescent assays.
Article
Chemistry, Physical
G. B. Oliveira-Filho, J. J. Atoche-Medrano, F. F. H. Aragon, J. C. Mantilla Ochoa, D. G. Pacheco-Salazar, S. W. da Silva, J. A. H. Coaquira
Summary: Core-shell structure Au@Fe3O4 nanoparticles were synthesized using a thermal decomposition method, with a core diameter of approximately 10.5 nm and a shell thickness of roughly 1.85 nm. The nanocomposite exhibited a successful coupling of Au and Fe3O4, possessing good crystal structure and magnetic response characteristics.
APPLIED SURFACE SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Venkatachalam Rajagopal, Annadurai Thamilselvan, Noel Nesakumar, Vembu Suryanarayanan
Summary: This study analyzed the use of Au@Fe3O4@rGO nanocomposite material for sensor applications in the detection of acetaminophen. The modified electrode showed good electrochemical sensitivity and performance, with a low limit of detection and high sensitivity for acetaminophen detection. The sensor was also effective in detecting acetaminophen in human urine samples.
MATERIALS TODAY COMMUNICATIONS
(2021)
Review
Chemistry, Analytical
Donato Calabria, Maria Maddalena Calabretta, Martina Zangheri, Elisa Marchegiani, Ilaria Trozzi, Massimo Guardigli, Elisa Michelini, Fabio Di Nardo, Laura Anfossi, Claudio Baggiani, Mara Mirasoli
Summary: Paper-based lateral-flow immunoassays have achieved commercial success and are continuously growing in the field of diagnostics. These assays, which provide qualitative information about the target analyte, have the potential to be adapted for ultrasensitive quantitative analysis.
Article
Environmental Sciences
Jiankun Feng, Yuan Xue, Xinwei Wang, Qingsong Song, Baojian Wang, Xuexiang Ren, Leigang Zhang, Zhenjiang Liu
Summary: A dual lateral flow immunoassay (LFIA) integrated with a smartphone was developed for simultaneous and quantitative detection of DON and FB1 in water. The method showed improved sensitivity, good specificity, and a dynamic linear detection for both mycotoxins.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
