Identification of a bet-hedging network motif generating noise in hormone concentrations and germination propensity in Arabidopsis

Temperature variability is integrated by a spatially embedded decision-making center to break dormancy inArabidopsisseeds

(2017) Alexander T. Topham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evolution of Cell-to-Cell Variability in Stochastic, Controlled, Heteroplasmic mtDNA Populations

(2016) Iain G. Johnston et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Developmental mechanisms underlying variable, invariant and plastic phenotypes

(2016) Katie Abley et al.   ANNALS OF BOTANY

Accurate concentration control of mitochondria and nucleoids

(2016) R. Jajoo et al.   SCIENCE

To Grow or not to Grow?

(2016) George W. Bassel   TRENDS IN PLANT SCIENCE

Seed vigour and crop establishment: extending performance beyond adaptation

(2015) W.E. Finch-Savage et al.   JOURNAL OF EXPERIMENTAL BOTANY

Closed-form stochastic solutions for non-equilibrium dynamics and inheritance of cellular components over many cell divisions

(2015) Iain G. Johnston et al.   PROCEEDINGS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES

Applying developmental threshold models to evolutionary ecology

(2015) Kathleen Donohue et al.   TRENDS IN ECOLOGY & EVOLUTION

Stochastic modelling, Bayesian inference, and new in vivo measurements elucidate the debated mtDNA bottleneck mechanism

(2015) Iain G Johnston et al.   eLife

Amplification of ABA biosynthesis and signaling through a positive feedback mechanism in seeds

(2014) Mariko Nonogaki et al.   PLANT JOURNAL

Noise in biology

(2014) Lev S Tsimring   REPORTS ON PROGRESS IN PHYSICS

Efficient parametric inference for stochastic biological systems with measured variability

(2014) Iain G. Johnston   Statistical Applications in Genetics and Molecular Biology

Mitochondrial Variability as a Source of Extrinsic Cellular Noise

(2012) Iain G. Johnston et al.   PLoS Computational Biology

Environmental versatility promotes modularity in genome-scale metabolic networks

(2011) Areejit Samal et al.   BMC Systems Biology

Dormancy cycling in Arabidopsis seeds is controlled by seasonally distinct hormone-signaling pathways

(2011) S. Footitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Heterogeneity: Do Differences Make a Difference?

(2010) Steven J. Altschuler et al.   CELL

Fundamental limits on the suppression of molecular fluctuations

(2010) Ioannis Lestas et al.   NATURE

Comprehensive Hormone Profiling in Developing Arabidopsis Seeds: Examination of the Site of ABA Biosynthesis, ABA Transport and Hormone Interactions

(2010) Yuri Kanno et al.   PLANT AND CELL PHYSIOLOGY

A chance at survival: gene expression noise and phenotypic diversification strategies

(2009) Dawn Fraser et al.   MOLECULAR MICROBIOLOGY

Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis

(2009) Sabrina L. Spencer et al.   NATURE

Non-genetic heterogeneity — a mutation-independent driving force for the somatic evolution of tumours

(2009) Amy Brock et al.   NATURE REVIEWS GENETICS

Morphogen profiles can be optimized to buffer against noise

(2009) Timothy E. Saunders et al.   PHYSICAL REVIEW E

Major flowering time gene,FLOWERING LOCUS C, regulates seed germination inArabidopsis thaliana

(2009) George C. K. Chiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Noise Management by Molecular Networks

(2009) Frank J. Bruggeman et al.   PLoS Computational Biology

Nature, Nurture, or Chance: Stochastic Gene Expression and Its Consequences

(2008) Arjun Raj et al.   CELL

Transcriptome-wide noise controls lineage choice in mammalian progenitor cells

(2008) Hannah H. Chang et al.   NATURE