Article
Biochemistry & Molecular Biology
Masato Ishizaka, Minghao Chen, Shun Narai, Yoshikazu Tanaka, Toyoyuki Ose, Masaki Horitani, Min Yao
Summary: Iron-sulfur (Fe-S) clusters play a vital role in enzyme activity. This study focuses on the relationship between the Fe-S cluster type and the catalytic activity of a tRNA-thiolation enzyme (TtuA). The researchers observed that [3Fe-4S]-TtuA spontaneously transforms into [4Fe-4S]-TtuA within minutes to an hour, and [3Fe-4S]-TtuA is highly inactive and unstable. These findings provide insights into the Fe-S cluster type used by the tRNA-thiolation enzyme.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Yugang Zhang, Dan Su, Boris Dzikovski, Sean H. Majer, Rachael Coleman, Siddarth Chandrasekaran, Michael K. Fenwick, Brian R. Crane, Kyle M. Lancaster, Jack H. Freed, Hening Lin
Summary: All radical-SAM enzymes require a [4Fe-4S](Cys)(3) cluster for activity, which is highly air-sensitive. A study on yeast Dph1-Dph2 revealed that the iron-containing protein Dph3 donates an iron atom to convert a [3Fe-4S] cluster to a functional [4Fe-4S] cluster, maintaining radical-SAM enzyme activity in aerobic environments.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Physical
Wail Al Zoubi, Rosy Amalia Kurnia Putri, Baeki Sunghun, Young Gun Ko
Summary: In this study, plasma-assisted electrochemical reactions on the metal surface of light metals were investigated using low temperature-interfacial plasma electrolysis in the presence of nitrogen-containing organic compounds. It was found that the addition of Melamine (MEL) and N.N.N'.N'-tetramethylenediamine (TEMD) promoted the formation of magnesium oxide and magnesium silicate, leading to improved corrosion protection.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Multidisciplinary Sciences
Samuel L. Rose, Seiki Baba, Hideo Okumura, Svetlana Antonyuk, Daisuke Sasaki, Tobias M. Hedison, Muralidharan Shanmugam, Derren J. Heyes, Nigel S. Scrutton, Takashi Kumasaka, Takehiko Tosha, Robert R. Eady, Masaki Yamamoto, S. Samar Hasnain
Summary: Redox reactions play a crucial role in substrate binding and utilization in enzyme catalysis. A recent study found that a CuNiR with lower catalytic activity had its catalytic site occupied by water molecules. The study showed that there was less inter-Cu electron transfer in the presence of nitrite, which may explain the lower activity.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Chemistry, Multidisciplinary
Valtteri Oksanen, Sari Rautiainen, Tom Wirtanen
Summary: This study presents a nickel-bipyridine electrocatalyzed homocoupling method for synthesizing bifuran motifs, using bromine-substituted methyl furancarboxylates prepared from hemicellulose-derived furfural. The protocol utilizes sustainable carbon-based graphite electrodes in a simple setup and avoids the use of a sacrificial anode by employing triethanolamine as an electron donor. The nickel-electrocatalyzed homocoupling is applied to the preparation of bifuran-based monomers, which are isolated using precipitation.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Electrochemistry
Tanika Duivenvoorden, Stephen Sanderson, Debra J. Searles
Summary: Lithium-sulfur (LS) batteries have high theoretical energy density, making them a promising alternative to conventional battery technologies. However, the insulating nature of sulfur and the polysulfide shuttle effect present challenges to achieving this high energy density. This study uses molecular dynamics simulations to investigate the structure of LS battery cathode-electrolyte interfaces. The results show that the size of graphene flakes used in the cathode material affects the bonding between graphene and sulfur and the presence of long-chain sulfur species. The simulations also reveal that the orientation of cathode structures with larger graphene flakes can shield the long-chain sulfur and lithium polysulfide species from interacting with the electrolyte. The study highlights the need for further development of reactive force fields to fully understand the range of structures in LS batteries and optimize their performance.
BATTERIES & SUPERCAPS
(2023)
Review
Chemistry, Physical
Avery C. Vilbert, Yiwei Liu, Huiguang Dai, Yi Lu
Summary: Metalloenzymes, performing reactions at low overpotentials with earth-abundant metals, are ideal candidates for inspiring electrocatalytic design. The redox-active metal centers surrounding the active site ensure efficient electron transfer and tuning the catalytic potential of the reaction, playing a crucial role in determining the catalytic bias of the reaction. Recent advances in studying these electron transfer centers in enzymes provide insights into how the reduction potential affects reactivity at the active site.
CURRENT OPINION IN ELECTROCHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Marino F. A. Santos, Giuseppe Sciortino, Isabel Correia, Andreia C. P. Fernandes, Teresa Santos-Silva, Federico Pisanu, Eugenio Garribba, Joao Costa Pessoa
Summary: This study investigates the interaction between vanadium compounds and proteins, revealing the relevance of hydrolysis and the formation of different adducts in these interactions.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Multidisciplinary Sciences
Sonia Jafari, Ulf Ryde, Mehdi Irani
Summary: [4Fe-4S] clusters are essential cofactors in proteins involved in biological redox-active processes. This study investigates the structural diversity and stability of these clusters in proteins by combining quantum mechanical and molecular mechanical methods. The results suggest the existence of two local minima, with the L state being more stable and having longer Fe-Fe distances than the S state. It is also found that different DFT methods may yield different results. The study highlights the importance of reliable DFT methods and geometry optimization, and recommends the use of r(2)SCAN for optimizing [4Fe-4S] clusters in proteins.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Physical
Bidyut K. Rana, Gourisankar Roymahapatra, Himadri Sekhar Das, Santanab Giri, Marlon H. Cardoso, Octavio L. Franco, N. K. Kiran, Manas K. Santra, Partha Pratim Bag, Valerio Bertolasi, Joydev Dinda
Summary: A new set of Ru-N-Heterocyclic Carbene (Ru-NHC) complexes were synthesized, characterized, and evaluated for their cytotoxicity activity on various cancer cells.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Physical
Bidyut K. Rana, Gourisankar Roymahapatra, Himadri Sekhar Das, Santanab Giri, Marlon H. Cardoso, Octavio L. Franco, Kiran K. Nakka, Manas K. Santra, Partha Pratim Bag, Valerio Bertolasi, Joydev Dinda
Summary: A new set of Ru-N-Heterocyclic Carbene (Ru-NHC) complexes were synthesized and their structures were investigated through X-ray diffraction, showing a half-sandwich geometry. The absorption spectra and electrochemical behavior of the complexes were evaluated, along with in vitro cytotoxicity testing on lung, colon, and breast cancer cells.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Materials Science, Multidisciplinary
Suzue Yoneda, Shigenari Hayashi, Yasuki Miyakoshi, Takashi Kogin, Eiji Ishikawa, Manabu Noguchi
Summary: The erosion-corrosion rate of alloy is influenced by the molybdenum content and the structural change of the oxide scale. The erosion-corrosion rate of molybdenum-free alloy decreased over time, while the molybdenum-containing alloy displayed accelerated erosion-corrosion.
Article
Chemistry, Inorganic & Nuclear
Zhenyu Shi, Wei Hu, Yuguo Zheng, Xiao-Yang Yu, Guanghui Jian, Xia Yu, Qingqing Guo, Chengjiang Fang, Yanyan Yang, Xiaoshu Qu
Summary: By regulating the initial reactant molar ratio, two new copper-organic complexes have been successfully synthesized. These compounds exhibit multifunctionality, including photocatalytic degradation and electrocatalytic reduction/oxidation reactions, as well as good electrochemical sensing properties.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Applied
Wei Deng, Xuepeng Wang, Chun Ho Lam, Zhe Xiong, Hengda Han, Jun Xu, Long Jiang, Sheng Su, Song Hu, Yi Wang, Jun Xiang
Summary: The electrochemical method is a novel option for bio-oil upgrading due to its mild reaction conditions, control convenience, and carbon neutrality. During electrochemical processing of bio-oil, coke is mainly formed from the polymerization of aromatic components, with reaction time and current density having a promoting effect on coke yields.
FUEL PROCESSING TECHNOLOGY
(2022)
Article
Chemistry, Organic
Wataru Setaka, Kazuki Kajiyama, Yusuke Inagaki
Summary: Phenylenediamine derivatives have been investigated for their oxidation properties, and in this study, the effects of macroring size on the structures and oxidation properties of phenylene-bridged diazacycloalkanes were examined. The structures around the nitrogen atoms were found to depend on the chain lengths, and the stabilization resulting from conjugation was comparable to destabilization caused by macroring strain. Structural differences between the synthesized compounds caused changes in NMR chemical shifts and first oxidation potentials in solution. The properties of one of the synthesized compounds, C12, were found to be of interest due to its distributed structure.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
