4.4 Article Proceedings Paper

The duration of sexual relationship and its effects on adverse pregnancy outcomes

Journal

JOURNAL OF REPRODUCTIVE IMMUNOLOGY
Volume 128, Issue -, Pages 16-22

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.jri.2018.05.007

Keywords

Duration of sexual relationship; Preeclampsia; Gestational hypertension; SGA; Uterine artery doppler

Funding

  1. Premier's Science and Research Fund, South Australian Government
  2. New Enterprise Research Fund, Foundation for Research Science and Technology
  3. Health Research Council [04/198]
  4. Evelyn Bond Fund, Auckland District Health Board Charitable Trust
  5. Health Research Board of Ireland [CSA/2007/2]
  6. National Health Service NEAT Grant [FSD025]
  7. Biotechnology and Biological Sciences Research council [GT084]
  8. University of Manchester
  9. Guy's and St Thomas' Charity (King's College London)
  10. Cerebra UK (University of Leeds)
  11. NHMRC Peter Doherty BioMedical Postdoctoral Fellowship [GNT1090778]
  12. University of Adelaide
  13. Tommy's charity (King's College London)
  14. Tommy's charity (University of Manchester)
  15. National Institutes of Health Research (NIHR) [FSD025] Funding Source: National Institutes of Health Research (NIHR)

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This study aims to determine if a short duration of sexual relationship is more common among women who experience adverse pregnancy outcomes including gestational hypertension (GHT), preeclampsia, small for gestational age (SGA) pregnancies and spontaneous preterm birth (sPTB) with or without abnormal uterine artery Doppler compared to women who have uncomplicated pregnancies. 5591 nulliparous women from the Screening for Pregnancy Endpoints (SCOPE) study were included. The risk for pregnancy complications for women who had a duration of sexual relationship of 3 months, 4-6 months, 7-9 months, 10-12 months was compared with women who had a duration of sexual relationship of > 12 months. Uterine artery Doppler was performed at 20 +/- 1 weeks' gestation. A short duration of sexual relationship (<= 3 months) was more common among women with SGA in the presence of abnormal uterine artery Doppler [9.8% vs 3.0%, aOR (95% CI) 3.4 (1.6-7.08] compared to women who had uncomplicated pregnancies. A short duration of sexual relationship (<= 3 months) was also more common among women who had abnormal uterine artery Doppler compared to those with normal uterine artery Doppler [6.1% vs 3.1%, aOR (95% CI) = 2.1 (1.4-3.2)]. A short duration of sexual relationship was not associated with preeclampsia after adjusting for confounders. A short duration of sexual relationship is more common among women who deliver SGA infants with features of placental insufficiency as indicated by abnormal uterine artery Doppler.

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