Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches

Hippo Pathway Activity Influences Liver Cell Fate

(2014) Dean Yimlamai et al.   CELL

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment

(2014) A. Seth et al.   DEVELOPMENT

The biliary epithelium gives rise to liver progenitor cells

(2014) Daniel Rodrigo-Torres et al.   HEPATOLOGY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Polycystic liver disease: an overview of pathogenesis, clinical manifestations and management

(2014) Wybrich R Cnossen et al.   Orphanet Journal of Rare Diseases

Molecular physiology of the tensin brotherhood of integrin adaptor proteins

(2014) Donald T. Haynie   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Transitions between epithelial and mesenchymal states during cell fate conversions

(2014) Xiang Li et al.   Protein & Cell

Links Between Hepatic Fibrosis, Ductular Reaction, and Progenitor Cell Expansion

(2013) Michael J. Williams et al.   GASTROENTEROLOGY

Myofibroblastic cells function as progenitors to regenerate murine livers after partial hepatectomy

(2013) M Swiderska-Syn et al.   GUT

Binding between the Junctional Proteins Afadin and PLEKHA7 and Implication in the Formation of Adherens Junction in Epithelial Cells

(2013) Souichi Kurita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mesenchymal progenitor cells in mouse foetal liver regulate differentiation and proliferation of hepatoblasts

(2013) Keiichi Ito et al.   LIVER INTERNATIONAL

The Adherens Junction Protein Afadin Is an AKT Substrate that Regulates Breast Cancer Cell Migration

(2013) Sivan Elloul et al.   MOLECULAR CANCER RESEARCH

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

(2013) Neil C Henderson et al.   NATURE MEDICINE

Talins and kindlins: partners in integrin-mediated adhesion

(2013) David A. Calderwood et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrin-mediated regulation of TGFβ in fibrosis

(2012) Neil C. Henderson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation

(2012) Guanhua Xie et al.   GUT

Interplay between αvβ3Integrin and Nucleolin Regulates Human Endothelial and Glioma Cell Migration

(2012) Marina Koutsioumpa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Supervillin couples myosin-dependent contractility to podosomes and enables their turnover

(2012) R. Bhuwania et al.   JOURNAL OF CELL SCIENCE

Development of the bile ducts: Essentials for the clinical hepatologist

(2012) Mario Strazzabosco et al.   JOURNAL OF HEPATOLOGY

Pleiotrophin Suppression of Receptor Protein Tyrosine Phosphatase- /  Maintains the Self-Renewal Competence of Fetal Human Oligodendrocyte Progenitor Cells

(2012) C. R. McClain et al.   JOURNAL OF NEUROSCIENCE

Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease

(2012) Luke Boulter et al.   NATURE MEDICINE

Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche

(2012) Heather A. Himburg et al.   Cell Reports

Lineage tracing demonstrates no evidence of cholangiocyte epithelial-to-mesenchymal transition in murine models of hepatic fibrosis

(2011) Andrew S. Chu et al.   HEPATOLOGY

Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets

(2011) Vincenzo Cardinale et al.   HEPATOLOGY

Human cirrhosis: Monoclonal regenerative nodules derived from hepatic progenitor cells abutting ductular reaction

(2010) P. Bioulac-Sage et al.   GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE

Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine

(2010) Kenichiro Furuyama et al.   NATURE GENETICS

Pleiotrophin regulates the expansion and regeneration of hematopoietic stem cells

(2010) Heather A Himburg et al.   NATURE MEDICINE

The Membrane-Associated Protein, Supervillin, Accelerates F-Actin-Dependent Rapid Integrin Recycling and Cell Motility

(2010) Zhiyou Fang et al.   TRAFFIC

Integrin ανβ3 is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase β/ζ

(2009) Constantinos Mikelis et al.   FASEB JOURNAL

Inhibition of Integrin αvβ6 on Cholangiocytes Blocks Transforming Growth Factor-β Activation and Retards Biliary Fibrosis Progression

(2008) Eleonora Patsenker et al.   GASTROENTEROLOGY

Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development

(2008) Kinji Asahina et al.   HEPATOLOGY

Pleiotrophin inhibits transforming growth factor β1-induced apoptosis in hepatoma cell lines

(2008) Tae Jun Park et al.   MOLECULAR CARCINOGENESIS

Pleiotrophin induces nitric oxide dependent migration of endothelial progenitor cells

(2007) Christian Heiss et al.   JOURNAL OF CELLULAR PHYSIOLOGY