4.3 Article

Microneedles as Enhancer of Drug Absorption Through the Skin and Applications in Medicine and Cosmetology

Journal

Publisher

CANADIAN SOC PHARMACEUTICAL SCIENCES
DOI: 10.18433/jpps29610

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Funding

  1. CONACyT [272133]
  2. Catedra PIAPIC [1619]
  3. PAPIIT [IT 200218]
  4. PAPIME [PE 201418]

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The microneedles technology has found applications in many health-related fields. For example, their application in drugs and vaccines delivery as well, as the determination of biomarkers, has been reported. They also have a place in the dermatology and cosmetic areas such as the treatment of wounds from burns, scars, acne, depigmentation, and alopecia will be shown. Microneedles are used in therapeutic applications and are manufactured using materials such as metal (steel, titanium, nickel), polymer (oly-glycolic acid (PGA), poly-lactide-co-glycolide acid (PLGA), poly-L-lactic acid (PLA), chitosan), glass, silicon, ceramic, carbohydrates (trehalose, sucrose, mannitol). Examples of application of microneedles and their advantages and disadvantages are discussed.

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