Receptor/gene/protein-mediated signaling connects methylprednisolone exposure to metabolic and immune-related pharmacodynamic actions in liver

Mechanistic Multi—Tissue Modeling of Glucocorticoid-Induced Leucine Zipper Regulation: Integrating Circadian Gene Expression with Receptor-Mediated Corticosteroid Pharmacodynamics

(2017) Vivaswath S. Ayyar et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Functional proteomic analysis of corticosteroid pharmacodynamics in rat liver: Relationship to hepatic stress, signaling, energy regulation, and drug metabolism

(2017) Vivaswath S. Ayyar et al.   Journal of Proteomics

Understanding Physiology in the Continuum: Integration of Information from Multiple -Omics Levels

(2017) Kubra Kamisoglu et al.   Frontiers in Pharmacology

Identification and molecular characterization of cellular factors required for glucocorticoid receptor-mediated mRNA decay

(2016) Ok Hyun Park et al.   GENES & DEVELOPMENT

Tandem Analysis of Transcriptome and Proteome Changes after a Single Dose of Corticosteroid: A Systems Approach to Liver Function in Pharmacogenomics

(2015) Kubra Kamisoglu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Glucocorticoid receptor interacts with PNRC2 in a ligand-dependent manner to recruit UPF1 for rapid mRNA degradation

(2015) Hana Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STAT3-driven transcription depends upon the dimethylation of K49 by EZH2

(2015) Maupali Dasgupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The utility of protein and mRNA correlation

(2015) Samuel H. Payne   TRENDS IN BIOCHEMICAL SCIENCES

Highly Multiplexed and Reproducible Ion-Current-Based Strategy for Large-Scale Quantitative Proteomics and the Application to Protein Expression Dynamics Induced by Methylprednisolone in 60 Rats

(2014) Eslam Nouri-Nigjeh et al.   ANALYTICAL CHEMISTRY

Systematic Assessment of Survey Scan and MS2-Based Abundance Strategies for Label-Free Quantitative Proteomics Using High-Resolution MS Data

(2014) Chengjian Tu et al.   JOURNAL OF PROTEOME RESEARCH

Moving from Basic Toward Systems Pharmacodynamic Models

(2013) William J. Jusko   JOURNAL OF PHARMACEUTICAL SCIENCES

Mathematical modeling of the glucose–insulin system: A review

(2013) Pasquale Palumbo et al.   MATHEMATICAL BIOSCIENCES

Meta-Modeling of Methylprednisolone Effects on Glucose Regulation in Rats

(2013) Jing Fang et al.   PLoS One

Tissue-Specific Actions of Glucocorticoids on Apoptosis: A Double-Edged Sword

(2013) Amanda Gruver-Yates et al.   Cells

Glucocorticoid use and abuse in SLE

(2012) G. Ruiz-Irastorza et al.   RHEUMATOLOGY

Mechanistic Modeling of the Effects of Glucocorticoids and Circadian Rhythms on Adipokine Expression

(2011) S. Sukumaran et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Stimulation of Hepatic Acute Phase Response by Cytokines and Glucocorticoidsa

(2010) H. BAUMANN et al.   Annals of the New York Academy of Sciences

Pharmacodynamics of glucose regulation by methylprednisolone. II. normal rats

(2009) Jin Y. Jin et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Pharmacodynamics of glucose regulation by methylprednisolone. I. Adrenalectomized rats

(2009) Jin Y. Jin et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Correlation of mRNA and protein in complex biological samples

(2009) Tobias Maier et al.   FEBS LETTERS

Serpin B3/B4, activated by STAT3, promote survival of squamous carcinoma cells

(2008) Simi T. Ahmed et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mathematical Modeling of Corticosteroid Pharmacogenomics in Rat Muscle following Acute and Chronic Methylprednisolone Dosing

(2008) Zhenling Yao et al.   MOLECULAR PHARMACEUTICS

Pharmacokinetic/Pharmacodynamic Modeling of Corticosterone Suppression and Lymphocytopenia by Methylprednisolone in Rats

(2007) Zhenling Yao et al.   JOURNAL OF PHARMACEUTICAL SCIENCES