“Ghost peak” of clofazimine: A solution degradation product of clofazimine via nucleophilic substitution by nitrite leaching from certain glass HPLC vials

Published 2018 View Full Article

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Title
“Ghost peak” of clofazimine: A solution degradation product of clofazimine via nucleophilic substitution by nitrite leaching from certain glass HPLC vials
Authors
Keywords
Clofazimine, Nitrite esterification, LC–MS, NMR, Mechanism-based stress, Glass HPLC vial
Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 150, Issue -, Pages 183-190
Publisher
Elsevier BV
Online
2017-11-27
DOI
10.1016/j.jpba.2017.11.052

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