Journal
JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY
Volume 31, Issue 3, Pages 321-324Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jpag.2017.12.009
Keywords
Ovarian teratoma; Anti-NMDA receptor encephalitis; Glial fibrillary acidic protein (GFAP) meningoencephalitis; Autoimmune meningoencephalitis
Categories
Ask authors/readers for more resources
Background: Ovarian teratomas are rarely associated with paraneoplastic autoimmune meningoencephalitis. In addition to the well known N-methyl-D-aspartate receptor (NMDA-R) antibody, the glial fibrillary acidic protein (GFAP) antibody is a novel biomarker of autoimmune meningoencephalitis that might be seen in patients with ovarian teratoma. Case: A 13-year-old girl with acute-onset meningoencephalitis and incidental finding of ovarian teratoma was found to have coexisting anti-NMDA-R and GFAP antibodies present in her cerebrospinal fluid. Summary and Conclusion: NMDA-R and GFAP autoimmune encephalitis should be considered in adolescent patients with neurologic or psychiatric symptoms and an ovarian teratoma. Prompt diagnosis and surgical resection increase the likelihood of full neurologic recovery.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available