Vascular targeting of LIGHT normalizes blood vessels in primary brain cancer and induces intratumoural high endothelial venules

Efficacy of NGR peptide-modified PEGylated quantum dots for crossing the blood–brain barrier and targeted fluorescence imaging of glioma and tumor vasculature

(2017) Ning Huang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Combined antiangiogenic and anti–PD-L1 therapy stimulates tumor immunity through HEV formation

(2017) Elizabeth Allen et al.   Science Translational Medicine

History and current state of immunotherapy in glioma and brain metastasis

(2017) Tresa McGranahan et al.   Therapeutic Advances in Medical Oncology

Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy

(2016) Anna Rita Cantelmo et al.   CANCER CELL

Ipilimumab and Bevacizumab in Glioblastoma

(2016) T. Carter et al.   CLINICAL ONCOLOGY

Intratumoral tertiary lymphoid organ is a favourable prognosticator in patients with pancreatic cancer

(2015) N Hiraoka et al.   BRITISH JOURNAL OF CANCER

Lessons From Anti–Vascular Endothelial Growth Factor and Anti–Vascular Endothelial Growth Factor Receptor Trials in Patients With Glioblastoma

(2015) Christine Lu-Emerson et al.   JOURNAL OF CLINICAL ONCOLOGY

Intratumoral LIGHT Restores Pericyte Contractile Properties and Vessel Integrity

(2015) Anna Johansson-Percival et al.   Cell Reports

Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent Model

(2015) D. A. Reardon et al.   Cancer Immunology Research

The tumor vessel targeting agent NGR-TNF controls the different stages of the tumorigenic process in transgenic mice by distinct mechanisms

(2015) Simona Porcellini et al.   OncoImmunology

Antiangiogenesis Strategies Revisited: From Starving Tumors to Alleviating Hypoxia

(2014) Rakesh K. Jain   CANCER CELL

Immunotherapy for Primary Brain Tumors: No Longer a Matter of Privilege

(2014) P. E. Fecci et al.   CLINICAL CANCER RESEARCH

A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma

(2014) Mark R. Gilbert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma

(2014) Olivier L. Chinot et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of the Lymphotoxin/LIGHT System in the Development and Maintenance of Reticular Networks and Vasculature in Lymphoid Tissues

(2014) Theresa T. Lu et al.   Frontiers in Immunology

Macrophage Regulation of Tumor Responses to Anticancer Therapies

(2013) Michele De Palma et al.   CANCER CELL

Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma

(2013) C. Lu-Emerson et al.   NEURO-ONCOLOGY

License for destruction: Tumor-specific cytokine targeting

(2013) Anna Johansson et al.   TRENDS IN MOLECULAR MEDICINE

Phase II study of NGR-hTNF in combination with doxorubicin in relapsed ovarian cancer patients

(2012) D Lorusso et al.   BRITISH JOURNAL OF CANCER

VEGF Inhibits Tumor Cell Invasion and Mesenchymal Transition through a MET/VEGFR2 Complex

(2012) Kan V. Lu et al.   CANCER CELL

Tumor-targeted TNF  stabilizes tumor vessels and enhances active immunotherapy

(2012) A. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dedifferentiation of Neurons and Astrocytes by Oncogenes Can Induce Gliomas in Mice

(2012) D. Friedmann-Morvinski et al.   SCIENCE

High endothelial venules (HEVs) in human melanoma lesions

(2012) Ludovic Martinet et al.   OncoImmunology

Angiogenesis in meningiomas

(2011) Valeria Barresi   Brain Tumor Pathology

Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer

(2011) L. Martinet et al.   CANCER RESEARCH

Phase I Study of NGR-hTNF, a Selective Vascular Targeting Agent, in Combination with Cisplatin in Refractory Solid Tumors

(2011) V. Gregorc et al.   CLINICAL CANCER RESEARCH

Enhanced Expression of CD13 in Vessels of Inflammatory and Neoplastic Tissues

(2011) Paola Di Matteo et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Targeted Drug Delivery and Penetration Into Solid Tumors

(2011) Angelo Corti et al.   MEDICINAL RESEARCH REVIEWS

Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma

(2011) L. Agemy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Corticosteroids in brain cancer patients: benefits and pitfalls

(2011) Jörg Dietrich et al.   Expert Review of Clinical Pharmacology

Nanoparticle-induced vascular blockade in human prostate cancer

(2010) L. Agemy et al.   BLOOD

Antiangiogenic Agents Can Increase Lymphocyte Infiltration into Tumor and Enhance the Effectiveness of Adoptive Immunotherapy of Cancer

(2010) R. K. Shrimali et al.   CANCER RESEARCH

Targeting of drugs and nanoparticles to tumors

(2010) Erkki Ruoslahti et al.   JOURNAL OF CELL BIOLOGY

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Tissue-Penetrating Delivery of Compounds and Nanoparticles into Tumors

(2009) Kazuki N. Sugahara et al.   CANCER CELL

Heterozygous Deficiency of PHD2 Restores Tumor Oxygenation and Inhibits Metastasis via Endothelial Normalization

(2009) Massimiliano Mazzone et al.   CELL

Targeted Liposomal Delivery of TLR9 Ligands Activates Spontaneous Antitumor Immunity in an Autochthonous Cancer Model

(2009) J. Hamzah et al.   JOURNAL OF IMMUNOLOGY

HIF1α Induces the Recruitment of Bone Marrow-Derived Vascular Modulatory Cells to Regulate Tumor Angiogenesis and Invasion

(2008) Rose Du et al.   CANCER CELL

Vascular targeting of anti-CD40 antibodies and IL-2 into autochthonous tumors enhances immunotherapy in mice

(2008) Juliana Hamzah et al.   JOURNAL OF CLINICAL INVESTIGATION