Nrf2 promotes oesophageal cancer cell proliferation via metabolic reprogramming and detoxification of reactive oxygen species

Integrated genomic characterization of oesophageal carcinoma

(2017)   NATURE

Effector T Cells Abrogate Stroma-Mediated Chemoresistance in Ovarian Cancer

(2016) Weimin Wang et al.   CELL

Transketolase counteracts oxidative stress to drive cancer development

(2016) Iris Ming-Jing Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tetrahydroanthraquinone Derivative (±)-4-Deoxyaustrocortilutein Induces Cell Cycle Arrest and Apoptosis in Melanoma Cells via Upregulation of p21 and p53 and Downregulation of NF-kappaB

(2016) Miroslav Genov et al.   Journal of Cancer

NRF2 regulates serine biosynthesis in non–small cell lung cancer

(2015) Gina M DeNicola et al.   NATURE GENETICS

NRF2 Mutation Confers Malignant Potential and Resistance to Chemoradiation Therapy in Advanced Esophageal Squamous Cancer

(2015) Tatsuhiro Shibata et al.   NEOPLASIA

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Clinical impact of the Warburg effect in gastrointestinal cancer (Review)

(2014) HIROSHI SAWAYAMA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Nrf2 affects the efficiency of mitochondrial fatty acid oxidation

(2013) Marthe H. R. Ludtmann et al.   BIOCHEMICAL JOURNAL

The Impact of miRNA-Based Molecular Diagnostics and Treatment of NRF2-Stabilized Tumors

(2013) Shinsuke Yamamoto et al.   MOLECULAR CANCER RESEARCH

Nrf2 Redirects Glucose and Glutamine into Anabolic Pathways in Metabolic Reprogramming

(2012) Yoichiro Mitsuishi et al.   CANCER CELL

The Keap1–Nrf2 system in cancers: stress response and anabolic metabolism

(2012) Yoichiro Mitsuishi et al.   Frontiers in Oncology

The Impact of 18F-Fluorodeoxyglucose Positron Emission Tomography Positive Lymph Nodes on Postoperative Recurrence and Survival in Resectable Thoracic Esophageal Squamous Cell Carcinoma

(2011) Takushi Yasuda et al.   ANNALS OF SURGICAL ONCOLOGY

CD44 Variant Regulates Redox Status in Cancer Cells by Stabilizing the xCT Subunit of System xc− and Thereby Promotes Tumor Growth

(2011) Takatsugu Ishimoto et al.   CANCER CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

p38 MAPK–mediated regulation of Xbp1s is crucial for glucose homeostasis

(2011) Jaemin Lee et al.   NATURE MEDICINE

The Keap1–Nrf2 system as an in vivo sensor for electrophiles

(2011) Akira Uruno et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

18F-FAMT-PET Is Useful for the Diagnosis of Lymph Node Metastasis in Operable Esophageal Squamous Cell Carcinoma

(2010) Makoto Sohda et al.   ANNALS OF SURGICAL ONCOLOGY

7th Edition of the AJCC Cancer Staging Manual: Esophagus and Esophagogastric Junction

(2010) Thomas W. Rice et al.   ANNALS OF SURGICAL ONCOLOGY

Nrf2 and Keap1 Abnormalities in Non-Small Cell Lung Carcinoma and Association with Clinicopathologic Features

(2010) L. M. Solis et al.   CLINICAL CANCER RESEARCH

Loss of Kelch-Like ECH-Associated Protein 1 Function in Prostate Cancer Cells Causes Chemoresistance and Radioresistance and Promotes Tumor Growth

(2010) P. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Response to Preoperative Therapy in Upper Gastrointestinal Cancers

(2009) Björn L. D. M. Brücher et al.   ANNALS OF SURGICAL ONCOLOGY

Centralization of Esophageal Cancer Surgery: Does It Improve Clinical Outcome?

(2009) M. W. J. M. Wouters et al.   ANNALS OF SURGICAL ONCOLOGY

MicroRNA-21 Regulates the Proliferation and Invasion in Esophageal Squamous Cell Carcinoma

(2009) Y. Hiyoshi et al.   CLINICAL CANCER RESEARCH

Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin

(2009) Yoo Ri Kim et al.   JOURNAL OF PATHOLOGY

p38MAPK: stress responses from molecular mechanisms to therapeutics

(2009) Lydia R. Coulthard et al.   TRENDS IN MOLECULAR MEDICINE

Hypermethylation of the Keap1 gene in human lung cancer cell lines and lung cancer tissues

(2008) Rui Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Tumor Cell Metabolism: Cancer's Achilles' Heel

(2008) Guido Kroemer et al.   CANCER CELL

RNAi-Mediated Silencing of Nuclear Factor Erythroid-2-Related Factor 2 Gene Expression in Non-Small Cell Lung Cancer Inhibits Tumor Growth and Increases Efficacy of Chemotherapy

(2008) A. Singh et al.   CANCER RESEARCH

The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation

(2008) Ralph J. DeBerardinis et al.   Cell Metabolism

Tumor Cell Metabolism Imaging

(2008) C. Plathow et al.   JOURNAL OF NUCLEAR MEDICINE

Regulation of glutathione synthesis

(2008) Shelly C. Lu   MOLECULAR ASPECTS OF MEDICINE

Ras oncogenes: split personalities

(2008) Antoine E. Karnoub et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

(2008) T. Shibata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA