HVR1-mediated antibody evasion of highly infectious in vivo adapted HCV in humanised mice

Immunoglobulin with High-TiterIn VitroCross-Neutralizing Hepatitis C Virus Antibodies Passively Protects Chimpanzees from Homologous, but Not Heterologous, Challenge

(2015) Jens Bukh et al.   JOURNAL OF VIROLOGY

Efficacy of a Tetravalent Dengue Vaccine in Children in Latin America

(2015) Luis Villar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Successful anti-scavenger receptor class B type I (SR-BI) monoclonal antibody therapy in humanized mice after challenge with HCV variants within vitroresistance to SR-BI-targeting agents

(2014) Koen Vercauteren et al.   HEPATOLOGY

Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses

(2014) William O. Osburn et al.   HEPATOLOGY

A new class of highly potent, broadly neutralizing antibodies isolated from viremic patients infected with dengue virus

(2014) Wanwisa Dejnirattisai et al.   NATURE IMMUNOLOGY

The Humoral Immune Response to HCV: Understanding is Key to Vaccine Development

(2014) Siobhán B. Cashman et al.   Frontiers in Immunology

Neutralizing Antibodies Induced by Cell Culture–Derived Hepatitis C Virus Protect Against Infection in Mice

(2013) Daisuke Akazawa et al.   GASTROENTEROLOGY

Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: Updated criteria and genotype assignment web resource

(2013) Donald B. Smith et al.   HEPATOLOGY

Neutralization resistance of hepatitis C virus can be overcome by recombinant human monoclonal antibodies

(2013) Jannie Pedersen et al.   HEPATOLOGY

Hypervariable Region 1 Deletion and Required Adaptive Envelope Mutations Confer Decreased Dependency on Scavenger Receptor Class B Type I and Low-Density Lipoprotein Receptor for Hepatitis C Virus

(2013) J. Prentoe et al.   JOURNAL OF VIROLOGY

Genetic and Functional Characterization of the N-Terminal Region of the Hepatitis C Virus NS2 Protein

(2013) C. de la Fuente et al.   JOURNAL OF VIROLOGY

Cell-culture-derived HCV—a promising vaccine antigen

(2013) Judith M. Gottwein et al.   Nature Reviews Gastroenterology & Hepatology

Structural evidence for a bifurcated mode of action in the antibody-mediated neutralization of hepatitis C virus

(2013) L. Deng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

(2013) J. S. McLellan et al.   SCIENCE

Animal Models for the Study of Hepatitis C Virus Infection and Related Liver Disease

(2012) Jens Bukh   GASTROENTEROLOGY

Mutations That Alter Use of Hepatitis C Virus Cell Entry Factors Mediate Escape From Neutralizing Antibodies

(2012) Isabel Fofana et al.   GASTROENTEROLOGY

Toward a Hepatitis C Virus Vaccine: the Structural Basis of Hepatitis C Virus Neutralization by AP33, a Broadly Neutralizing Antibody

(2012) J. A. Potter et al.   JOURNAL OF VIROLOGY

Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus

(2012) E. Giang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivoevaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus

(2011) Philip Meuleman et al.   HEPATOLOGY

The Hepatitis C Virus Glycan Shield and Evasion of the Humoral Immune Response

(2011) François Helle et al.   Viruses-Basel

Hepatitis C Virus Hypervariable Region 1 Modulates Receptor Interactions, Conceals the CD81 Binding Site, and Protects Conserved Neutralizing Epitopes

(2010) D. Bankwitz et al.   JOURNAL OF VIROLOGY

Novel Infectious cDNA Clones of Hepatitis C Virus Genotype 3a (Strain S52) and 4a (Strain ED43): Genetic Analyses and In Vivo Pathogenesis Studies

(2010) J. M. Gottwein et al.   JOURNAL OF VIROLOGY

Hypervariable Region 1 Differentially Impacts Viability of Hepatitis C Virus Strains of Genotypes 1 to 6 and Impairs Virus Neutralization

(2010) J. Prentoe et al.   JOURNAL OF VIROLOGY

Experimental models for hepatitis C viral infection

(2009) Andre Boonstra et al.   HEPATOLOGY

Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver–chimeric mice from infection with a homologous hepatitis C virus strain

(2008) Thomas Vanwolleghem et al.   HEPATOLOGY

Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization

(2008) T. K. H. Scheel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus

(2008) R. S. Russell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA