Eco-friendly synthesis of diverse and valuable 2-pyridones by catalyst- and solvent-free thermal multicomponent domino reaction

An efficient tandem approach for the synthesis of functionalized 2-pyridone-3-carboxylic acids using three-component reaction in aqueous media

(2014) Saber Mehrparvar et al.   MOLECULAR DIVERSITY

A versatile domino process for the synthesis of substituted 3-aminomethylene-chromanones and 2-pyridones catalyzed by CsF

(2013) Catalin Pintiala et al.   TETRAHEDRON LETTERS

Synthesis and structure–activity relationship of 5-substituent-2(1H)-pyridone derivatives as anti-fibrosis agents

(2012) Jun Chen et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and evaluation of novel 2-pyridone derivatives as inhibitors of phosphodiesterase3 (PDE3): A target for heart failure and platelet aggregation

(2012) Mettu Ravinder et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

FeCl3⋅6H2O-Catalyzed Intermolecular-Cascade Cyclization of Acetoacetanilide: Aldehyde-Tuned Synthesis to Valuable 2-Pyridone Analogues

(2012) Tista Sengupta et al.   CHEMISTRY-A EUROPEAN JOURNAL

2-Pyridone Synthesis Using 2-(Phenylsulfinyl)acetamide

(2012) Masaya Fujii et al.   ORGANIC LETTERS

Antifungal Spectrum, In Vivo Efficacy, and Structure–Activity Relationship of Ilicicolin H

(2012) Sheo B. Singh et al.   ACS Medicinal Chemistry Letters

[4+2+1] Domino cyclization in water for chemo- and regioselective synthesis of spiro-substituted benzo[b]furo[3,4-e][1,4]diazepine derivatives

(2011) Chuang Cheng et al.   GREEN CHEMISTRY

Synthesis of 6-Substituted-4-Hydroxy-2-pyridinones via Intramolecular Ketene Trapping of Functionalized Enamine-Dioxinones

(2011) Bhavesh H. Patel et al.   ORGANIC LETTERS

An expeditious, highly efficient, catalyst-free and solvent-free synthesis of nitroamines and nitrosulfides by Michael addition

(2010) Garima Choudhary et al.   GREEN CHEMISTRY

Pyridones as glucokinase activators: Identification of a unique metabolic liability of the 4-sulfonyl-2-pyridone heterocycle

(2009) Jeffrey A. Pfefferkorn et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Solvent-Free Heterocyclic Synthesis

(2009) Marcos A. P. Martins et al.   CHEMICAL REVIEWS

Energetic assessment of the Suzuki–Miyaura reaction: a curtate life cycle assessment as an easily understandable and applicable tool for reaction optimization

(2009) Franziska Schneider et al.   GREEN CHEMISTRY

Design, Synthesis, and Antihepatitis B Virus Activities of Novel 2-Pyridone Derivatives

(2009) Zhiliang Lv et al.   JOURNAL OF MEDICINAL CHEMISTRY

One-Pot Synthesis of 2-Pyridones via Chemo- and Regioselective Tandem Blaise Reaction of Nitriles with Propiolates

(2009) Yu Sung Chun et al.   JOURNAL OF ORGANIC CHEMISTRY

Microwave-Assisted Synthesis of Novel (5-Nitropyridin-2-yl)alkyl and (5-Nitropyridin-3-yl)alkyl Carbamates

(2009) Christophe Henry et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Alkenylation and Alkylation of Pyridone Derivatives by Ni/AlMe3Catalysis

(2009) Yoshiaki Nakao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluation of a 2-Pyridone, KRQ-10018, against Mycobacterium tuberculosis In Vitro and In Vivo

(2008) A. J. Lenaerts et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit†

(2008) Essa Hu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Biological Evaluation of 14-Substituted Aromathecins as Topoisomerase I Inhibitors

(2008) Maris A. Cinelli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Convergent and Rapid Assembly of Substituted 2-Pyridones through Formation ofN-Alkenyl Alkynylamides Followed by Gold-Catalyzed Cycloisomerization

(2008) Hidetomo Imase et al.   ORGANIC LETTERS