The distribution, clearance, and brainstem toxicity of panobinostat administered by convection-enhanced delivery

Convection enhanced delivery of panobinostat (LBH589)-loaded pluronic nano-micelles prolongs survival in the F98 rat glioma model

(2017) WG Singleton et al.   International Journal of Nanomedicine

Therapeutic Targeting of Histone Modifications in Adult and Pediatric High-Grade Glioma

(2017) Maria J. Williams et al.   Frontiers in Oncology

Pre-Clinical Study of Panobinostat in Xenograft and Genetically Engineered Murine Diffuse Intrinsic Pontine Glioma Models

(2017) Tammy Hennika et al.   PLoS One

Local delivery methods of therapeutic agents in the treatment of diffuse intrinsic brainstem gliomas

(2016) C. Rory Goodwin et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Convection-Enhanced Delivery for Diffuse Intrinsic Pontine Glioma Treatment

(2016) Zhiping Zhou et al.   Current Neuropharmacology

NS-21MULTI-CATHETER INTERMITTENT CONVECTION-ENHANCED DELIVERY OF CARBOPLATIN AS A TREATMENT FOR DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG): PRE-CLINICAL RATIONALE AND EARLY CLINICAL EXPERIENCE

(2016) William G.B. Singleton et al.   NEURO-ONCOLOGY

HG-36PLASMA AND CEREBROSPINAL FLUID (CSF) PHARMACOKINETICS OF PANOBINOSTAT FOLLOWING ORAL ADMINISTRATION TO NONHUMAN PRIMATES

(2016) Louis Rodgers et al.   NEURO-ONCOLOGY

Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma

(2016) Hamid Nikbakht et al.   Nature Communications

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes

(2015) David Castel et al.   ACTA NEUROPATHOLOGICA

DNA damage response and anti-apoptotic proteins predict radiosensitization efficacy of HDAC inhibitors SAHA and LBH589 in patient-derived glioblastoma cells

(2015) Lotte M.E. Berghauser Pont et al.   CANCER LETTERS

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

(2015) Catherine S Grasso et al.   NATURE MEDICINE

Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma

(2015) E. Q. Lee et al.   NEURO-ONCOLOGY

Convection-Enhanced Delivery of Carboplatin PLGA Nanoparticles for the Treatment of Glioblastoma

(2015) Azeem Arshad et al.   PLoS One

Future Clinical Trials in DIPG: Bringing Epigenetics to the Clinic

(2015) Andres Morales La Madrid et al.   Frontiers in Oncology

Pathology, Molecular Genetics, and Epigenetics of Diffuse Intrinsic Pontine Glioma

(2015) Pawel Buczkowicz et al.   Frontiers in Oncology

Epidemiology of Childhood Diarrhea in Rural North Pakistan: 20-Year Follow-Up From 1989–1996 to 2012–2014

(2015) Zeba Rasmussen et al.   Open Forum Infectious Diseases

A High-Throughput In Vitro Drug Screen in a Genetically Engineered Mouse Model of Diffuse Intrinsic Pontine Glioma Identifies BMS-754807 as a Promising Therapeutic Agent

(2015) Kyle G. Halvorson et al.   PLoS One

A novel implantable catheter system with transcutaneous port for intermittent convection-enhanced delivery of carboplatin for recurrent glioblastoma

(2014) Neil U. Barua et al.   DRUG DELIVERY

A twenty-year review of diagnosing and treating children with diffuse intrinsic pontine glioma in The Netherlands

(2014) Sophie EM Veldhuijzen van Zanten et al.   Expert Review of Anticancer Therapy

The potential of theragnostic 124I-8H9 convection-enhanced delivery in diffuse intrinsic pontine glioma

(2014) N. Luther et al.   NEURO-ONCOLOGY

Survival prediction model of children with diffuse intrinsic pontine glioma based on clinical and radiological criteria

(2014) Marc H. Jansen et al.   NEURO-ONCOLOGY

In vitro and in vivo testing of a novel recessed-step catheter for reflux-free convection-enhanced drug delivery to the brain

(2013) T. Gill et al.   JOURNAL OF NEUROSCIENCE METHODS

Intermittent convection-enhanced delivery to the brain through a novel transcutaneous bone-anchored port

(2013) N.U. Barua et al.   JOURNAL OF NEUROSCIENCE METHODS

Convection-enhanced delivery of AAV2 in white matter—A novel method for gene delivery to cerebral cortex

(2013) N.U. Barua et al.   JOURNAL OF NEUROSCIENCE METHODS

In Vitro Drug Response and Efflux Transporters Associated with Drug Resistance in Pediatric High Grade Glioma and Diffuse Intrinsic Pontine Glioma

(2013) Susanna J. E. Veringa et al.   PLoS One

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

(2012) Dong-Anh Khuong-Quang et al.   ACTA NEUROPATHOLOGICA

Anaesthetic complications in pigs undergoing MRI guided convection enhanced drug delivery to the brain: a case series

(2012) Alan Jones et al.   VETERINARY ANAESTHESIA AND ANALGESIA

The development of an implantable catheter system for chronic or intermittent convection-enhanced delivery

(2011) A. Bienemann et al.   JOURNAL OF NEUROSCIENCE METHODS

A robust MRI-compatible system to facilitate highly accurate stereotactic administration of therapeutic agents to targets within the brain of a large animal model

(2010) E. White et al.   JOURNAL OF NEUROSCIENCE METHODS