Article
Anatomy & Morphology
Tory O. Frizzell, Elisha Phull, Mishaa Khan, Xiaowei Song, Lukas A. Grajauskas, Jodie Gawryluk, Ryan C. N. D'Arcy
Summary: This study evaluated white matter neuroplasticity in healthy adults pre-post motor training, specifically focusing on motor learning in the non-dominant hand. Changes in neuroplasticity were observed in the internal capsule and corpus callosum, with significant amplitude reductions in low-frequency oscillations implicating optimized transmission through altered myelination. The findings open new avenues for white matter investigations and advance MRI clinical applications.
BRAIN STRUCTURE & FUNCTION
(2022)
Article
Oncology
Mia Andreoli, Melissa-Ann Mackie, David Aaby, Matthew C. Tate
Summary: This study investigates the relationship between white matter tract disruption and cognitive deficits in glioma patients using diffusion tensor imaging (DTI). The findings suggest that WM tract disruption predicts cognitive dysfunction in glioma patients, emphasizing the importance of understanding WM tract organization for surgical resection and functional preservation in these patients.
FRONTIERS IN ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Zexuan Hu, Peng Sun, Ajit George, Xiangling Zeng, Mengyan Li, Tsen-Hsuan Lin, Zezhong Ye, Xinhua Wei, Xinqing Jiang, Sheng-Kwei Song, Ruimeng Yang
Summary: Using diffusion basis spectrum imaging (DBSI) to examine the microstructural changes in the substantia nigra (SN) and global white matter (WM) tracts of patients with early-stage PD. The results showed that DBSI could potentially detect and quantify inflammatory cell infiltration, fiber/dendrite loss, and edema in both SN and WM tracts in patients with early-stage PD.
EUROPEAN RADIOLOGY
(2023)
Article
Neurosciences
Miriam H. A. Bopp, Julia Emde, Barbara Carl, Christopher Nimsky, Benjamin Sass
Summary: This study compared DTI- and DKI-based fiber tractography in CST, OR, and AF, finding that DKI showed significantly larger tract volumes in CST, similar results in OR with an exception in the right OR of patients, and comparable results in AF with DTI-based fiber tractography showing even significantly larger tract volumes in patients. DKI-based fiber tractography contributes to advanced visualization under clinical time constraints for CST and OR, while other models should be considered for AF.
Article
Clinical Neurology
Jian Yang, Xiaowei Jiang, Shengnan Wei, Xin Deng, Yue Zhu, Miao Chang, Zhiyang Yin, Haiyang Geng, Yanqing Tang, Xu Dai
Summary: Compared to DTI parameters, DKI parameters showed more sensitivity and stability in probing the local microstructure, especially in exploring cerebral alterations in BD patients.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Neuroimaging
Chao Wang, Shuyue Wang, Peiyu Huang, Zhujing Shen, Wei Qian, Xiao Luo, Kaicheng Li, Qingze Zeng, Quanquan Gu, Hualiang Yu, Yihong Yang, Minming Zhang
Summary: Nicotine addiction is associated with alterations in central reward pathways, with the insula playing a key role. Diffusion tensor imaging and probabilistic tractography revealed differences in white matter tracts of the insula between smokers and nonsmokers, suggesting potential insights into the neurobiology of nicotine addiction.
BRAIN IMAGING AND BEHAVIOR
(2021)
Article
Clinical Neurology
Arashk Mallahzadeh, Mahan Shafie, Mahdi Tahvilian, Mohammad Sadeghi, Golsa Moslemian, Pouria Barzin, Maryam Bemanalizadeh, Mahsa Mayeli, Mohammad Hadi Aarabi
Summary: Using diffusion MRI connectometry, this study found that the integrity of white matter in certain tracts is associated with behavioral activation and inhibition, expanding our knowledge of the neural networks associated with risk-taking and reward-seeking behaviors.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Manabu Tamura, Hiroyuki Kurihara, Taiichi Saito, Masayuki Nitta, Takashi Maruyama, Shunsuke Tsuzuki, Atsushi Fukui, Shunichi Koriyama, Takakazu Kawamata, Yoshihiro Muragaki
Summary: This study developed a navigation system that combines the fractional anisotropy (FA) color map of pre-operative diffusion tensor imaging (DTI) and intraoperative magnetic resonance imaging (MRI). The system was found to be useful for predicting the localization of critical white matter nerve functions during glioma surgery.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Lijun Deng, Rubo Sui, Lei Zhang
Summary: This study analyzed changes in white matter tracts in patients with post-stroke depression (PSD) and their correlation with depressive state. The results showed that fractional anisotropy (FA) and lines of specific white matter tracts in PSD patients were significantly correlated with HAMD scores, indicating their involvement in the development of PSD.
NEUROPSYCHIATRIC DISEASE AND TREATMENT
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiong Xiao, Ne Yang, Guocan Gu, Xianyu Wang, Zhuang Jiang, Tian Li, Xinran Zhang, Longfei Ma, Peng Zhang, Hongen Liao, Liwei Zhang
Summary: The study found that diffusion MRI is valuable in genotyping brainstem gliomas, with white matter tract measurements significantly improving diagnostic performance. Combining tumor and white matter features from diffusion tensor and kurtosis imaging can build the best genotyping model.
EUROPEAN RADIOLOGY
(2023)
Article
Neurosciences
Aiden Ford, Zeena Ammar, Longchuan Li, Sarah Shultz
Summary: Lateralization patterns in the brain white matter play a crucial role in cognitive specialization and behaviors, such as language skills. Many neurodevelopmental disorders have abnormal lateralization, highlighting the importance of studying this structural characteristic. However, there is no consensus on the direction and magnitude of lateralization during early infancy, and no longitudinal studies have been conducted to examine its changes over time. Using a longitudinal dataset of neurotypical infants aged 0-6 months, this study aims to chart the trajectories of white matter lateralization in major tracts and link them with findings from cross-sectional studies.
Article
Oncology
Jun Wang, Liang Yi, Qing-mei Kang, Ji Zhou, Tian-qing Chen, Jean-philippe Hugnot, Shi-cang Yu
Summary: Invasive growth along white matter tracts is a prominent clinicopathological feature of glioma and understanding the relevant clinical features and mechanisms is crucial for identifying new therapeutic targets and treatment strategies. Additionally, the correlation between glioma molecular typing, radiotherapy, TTFields, and glioma invasion along white matter tracts is also discussed.
Article
Neurosciences
Yanpeng Liu, Yiwei Xia, Xiaoxiao Wang, Yanming Wang, Du Zhang, Benedictor Alexander Nguchu, Jiajie He, Yi Wang, Lumeng Yang, Yiqing Wang, Yunqing Ying, Xiaoniu Liang, Qianhua Zhao, Jianjun Wu, Zonghui Liang, Ding Ding, Qiang Dong, Bensheng Qiu, Xin Cheng, Jia-Hong Gao
Summary: The study found that a high burden of white matter hyperintensities (WMH) is associated with worse diffusion characteristics of distal white matter tracts, which in turn affects attention and executive function.
HUMAN BRAIN MAPPING
(2021)
Article
Clinical Neurology
Stewart McLachlin, Jason Leung, Vignesh Sivan, Pierre-Olivier Quirion, Phoenix Wilkie, Julien Cohen-Adad, Cari Marisa Whyne, Michael Raymond Hardisty
Summary: Neuroimaging, specifically DTI tractography, is useful in complex spinal surgeries when anatomical geometry is distorted. This study aimed to evaluate the spatial correspondence of DTI tractography with anatomical MRI in healthy anatomy. The results showed good spatial correspondence of lateral corticospinal tract streamlines over a single vertebral ROI, but fair agreement over larger ROIs.
Article
Clinical Neurology
Melanie A. Matyi, Jeffrey M. Spielberg
Summary: Deficits in negative emotion differentiation are associated with mental health outcomes, but the processes underlying individual differences in negative emotion differentiation are poorly understood. This study examines the relationship between white matter microstructure and negative emotion differentiation, providing insights into its component processes and its link to brain structure.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Sophie H. A. E. Derks, Astrid A. M. van der Veldt, Marion Smits
Summary: Imaging techniques for brain metastases have greatly advanced in the past decade, addressing the challenges they pose in clinical practice. This review discusses the increased incidence of brain metastases from different primary tumors, the role of imaging in screening and detection, as well as its application in treatment planning and surveillance. Future perspectives, such as radiomics and new biomarkers, are also explored.
BRITISH JOURNAL OF RADIOLOGY
(2022)
Article
Oncology
Sebastian R. van der Voort, Fatih Incekara, Maarten M. J. Wijnenga, Georgios Kapsas, Renske Gahrmann, Joost W. Schouten, Rishi Nandoe Tewarie, Geert J. Lycklama, Philip C. De Witt Hamer, Roelant S. Eijgelaar, Pim J. French, Hendrikus J. Dubbink, Arnaud J. P. E. Vincent, Wiro J. Niessen, Martin J. van den Bent, Marion Smits, Stefan Klein
Summary: We developed a method that can non-invasively predict multiple clinically relevant features of glioma, and it performs well and generalizes well in an independent dataset.
Article
Oncology
Philipp Vollmuth, Martha Foltyn, Raymond Y. Huang, Norbert Galldiks, Jens Petersen, Fabian Isensee, Martin J. van den Bent, Frederik Barkhof, Ji Eun Park, Yae Won Park, Sung Soo Ahn, Gianluca Brugnara, Hagen Meredig, Rajan Jain, Marion Smits, Whitney B. Pope, Klaus Maier-Hein, Michael Weller, Patrick Y. Wen, Wolfgang Wick, Martin Bendszus
Summary: This study aimed to assess the reproducibility and standardization of treatment response assessment using artificial intelligence (AI) decision support in MRI. The results showed that AI decision support can provide better evaluation of treatment response in patients with lower-grade gliomas compared to manual measurements.
Article
Oncology
Mark P. van Opijnen, C. Mircea S. Tesileanu, Linda Dirven, Pim B. van der Meer, Maarten M. J. Wijnenga, Arnaud J. P. E. Vincent, Marike L. D. Broekman, Hendrikus J. Dubbink, Johan M. Kros, Sjoerd G. van Duinen, Marion Smits, Pim J. French, Martin J. van den Bent, Martin J. B. Taphoorn, Johan A. F. Koekkoek
Summary: IDHwt hLGG patients and IDHwt glioblastoma patients have similar incidence proportions of epilepsy during the entire disease course. However, the former has a significantly higher incidence of epilepsy before diagnosis and a significantly longer time between first seizure and diagnosis, indicating a distinct clinical course between the two subtypes.
Article
Audiology & Speech-Language Pathology
Marike Donders-Kamphuis, Arnaud Vincent, Joost Schouten, Marion Smits, Christa Docter-Kerkhof, Clemens Dirven, Alfred Kloet, Rishi Nandoe Tewarie, Djaina Satoer
Summary: This study aims to investigate the feasibility of awake surgery in glioblastoma patients with severe aphasia using a patient-tailored approach. Despite preoperative severe aphasia, functional boundaries for critical language areas could be identified in each patient, and postoperatively, all patients had stable or improved language outcome.
Meeting Abstract
Oncology
M. P. Van Opijnen, C. M. S. Tesileanu, L. Dirven, P. B. Van der Meer, M. M. J. Wijnenga, A. J. P. E. Vincent, M. L. D. Broekman, H. J. Dubbink, J. M. Kros, S. G. Van Duinen, M. Smits, P. J. French, M. J. Van den Bent, M. J. B. Taphoorn, J. A. F. Koekkoek
Article
Radiology, Nuclear Medicine & Medical Imaging
Thomas Lindner, Divya S. Bolar, Eric Achten, Frederik Barkhof, Antonio J. Bastos-Leite, John A. Detre, Xavier Golay, Matthias Guenther, Danny J. J. Wang, Sven Haller, Silvia Ingala, Hans R. Jaeger, Geon-Ho Jahng, Meher R. Juttukonda, Vera C. Keil, Hirohiko Kimura, Mai-Lan Ho, Maarten Lequin, Xin Lou, Jan Petr, Nandor Pinter, Francesca B. Pizzini, Marion Smits, Magdalena Sokolska, Greg Zaharchuk, Henk J. M. M. Mutsaerts
Summary: This article provides guidance on the clinical applications of arterial spin labeling (ASL) MRI, focusing on disease-specific considerations for sequence optimization and interpretation. It updates and expands on the recommendations from the 2015 ASL consensus paper, which lacked guidance on disease-specific parameters. The article covers various clinical scenarios, including acute ischemic stroke, brain tumors, and pediatric neuroradiology applications.
MAGNETIC RESONANCE IN MEDICINE
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Gilbert Hangel, Barbara Schmitz-Abecassis, Nico Sollmann, Joana Pinto, Fatemehsadat Arzanforoosh, Frederik Barkhof, Thomas Booth, Marta Calvo-Imirizaldu, Guilherme Cassia, Marek Chmelik, Patricia Clement, Ece Ercan, Maria A. Fernandez-Seara, Julia Furtner, Elies Fuster-Garcia, Matthew Grech-Sollars, N. Tugay Guven, Gokce Hale Hatay, Golestan Karami, Vera C. Keil, Mina Kim, Johan A. F. Koekkoek, Simran Kukran, Laura Mancini, Ruben Emanuel Nechifor, Alpay Ozcan, Esin Ozturk-Isik, Senol Piskin, Kathleen M. Schmainda, Siri F. Svensson, Chih-Hsien Tseng, Saritha Unnikrishnan, Frans Vos, Esther Warnert, Moss Y. Zhao, Radim Jancalek, Teresa Nunes, Lydiane Hirschler, Marion Smits, Jan Petr, Kyrre E. Emblem
Summary: Preoperative clinical MRI protocols for gliomas still rely on conventional structural MRI, which does not provide information on tumor genotype and has limitations in the delineation of diffuse gliomas. The GliMR COST action aims to raise awareness about advanced MRI techniques in gliomas and their potential clinical translation. This review summarizes current methods, limitations, and applications of advanced MRI for the preoperative assessment of glioma, and evaluates the level of clinical validation of different techniques.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Lydiane Hirschler, Nico Sollmann, Barbara Schmitz-Abecassis, Joana Pinto, Fatemehsadat Arzanforoosh, Frederik Barkhof, Thomas Booth, Marta Calvo-Imirizaldu, Guilherme Cassia, Marek Chmelik, Patricia Clement, Ece Ercan, Maria A. Fernandez-Seara, Julia Furtner, Elies Fuster-Garcia, Matthew Grech-Sollars, Nazmiye Tugay Guven, Gokce Hale Hatay, Golestan Karami, Vera C. Keil, Mina Kim, Johan A. F. Koekkoek, Simran Kukran, Laura Mancini, Ruben Emanuel Nechifor, Alpay Oezcan, Esin Ozturk-Isik, Senol Piskin, Kathleen Schmainda, Siri F. Svensson, Chih-Hsien Tseng, Saritha Unnikrishnan, Frans Vos, Esther Warnert, Moss Y. Zhao, Radim Jancalek, Teresa Nunes, Kyrre E. Emblem, Marion Smits, Jan Petr, Gilbert Hangel
Summary: This article introduces the preoperative clinical magnetic resonance imaging (MRI) protocols for gliomas, which still rely on conventional structural MRI. However, this method lacks information on tumor genotype and has limitations in delineating diffuse gliomas. The GliMR COST action aims to raise awareness and discuss the clinical translation of advanced MRI techniques for gliomas.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Review
Neurosciences
Sadaf Soloukey, Arnaud J. P. E. Vincent, Marion Smits, Chris I. De Zeeuw, Sebastiaan K. E. Koekkoek, Clemens M. F. Dirven, Pieter Kruizinga
Summary: Real-time imaging of brain functionality during neurosurgical procedures, such as craniotomy, is important for safe navigation. Current practice relies on limited techniques like electrical stimulation, but experimental imaging techniques show potential to improve decision-making and safety. These techniques also enhance our understanding of human brain function.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Oncology
Fatemeh Arzanforoosh, Sebastian R. R. van der Voort, Fatih Incekara, Arnaud Vincent, Martin Van den Bent, Johan M. M. Kros, Marion Smits, Esther A. H. Warnert
Summary: Reliable insight into tumor microvasculature is crucial for disease monitoring and treatment response. Vessel size imaging (VSI), an emerging MRI technique, has demonstrated potential in accurately revealing microvasculature information in gliomas. However, its clinical application is limited, which was investigated in this study.
Article
Oncology
Krishnapriya Venugopal, Fatemeh Arzanforoosh, Danielle van Dorth, Marion Smits, Matthias J. P. van Osch, Juan A. A. Hernandez-Tamames, Esther A. H. Warnert, Dirk H. J. Poot
Summary: Characterizing tumor microvasculature is crucial for tumor assessment and treatment response studies. This study proposes a magnetic resonance vascular fingerprinting (MRVF) technique using hybrid echo planar imaging (HEPI) based on dynamic susceptibility contrast (DSC). The approach was tested in patients with gliomas, enabling the simultaneous estimation of vessel radius and relative cerebral blood volume. The results were consistent with those obtained using the vessel size imaging (VSI) technique, and MRVF showed robustness in noise estimation. DSC-HEPI-based MRVF allows for efficient characterization of glioma microvasculature and can be further improved for better understanding of tumor physiology.
Review
Oncology
Dylan Henssen, Lars Leijten, Frederick J. A. Meijer, Anja van der Kolk, Anne I. J. Arens, Mark ter Laan, Robert J. Smeenk, Anja Gijtenbeek, Elsmarieke M. van de Giessen, Nelleke Tolboom, Daniela E. Oprea-Lager, Marion Smits, James Nagarajah
Summary: Sophisticated imaging techniques have been suggested for distinguishing tumor progression (TP) from treatment-related abnormalities (TRA) in post-treatment surveillance of gliomas. However, it remains unclear if any technique holds diagnostic superiority. This meta-analysis compared the diagnostic accuracy of different imaging techniques and found no superior technique.
Article
Radiology, Nuclear Medicine & Medical Imaging
Fatemeh Arzanforoosh, Avery J. L. Berman, Marion Smits, Esther A. H. Warnert
Summary: This study examined the ability of the streamlined quantitative (sq)BOLD MRI technique to detect and quantify changes in oxygenation in the healthy brain, and its potential application in clinical settings. The results showed that sqBOLD technique is sensitive enough to detect and quantify changes in oxygenation in the healthy brain, and it shows potential for providing valuable information on oxygenation in glioma in clinical settings.
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
(2023)
Article
Oncology
Karin A. van Garderen, Wies R. Vallentgoed, Anna Lavrova, Johanna M. Niers, Wendy W. J. de Leng, Youri Hoogstrate, Iris de Heer, Bauke Ylstra, Erik van Dijk, Stefan Klein, Kaspar Draaisma, Pierre A. J. T. Robe, Roel G. W. Verhaak, Bart A. Westerman, Pim J. French, Martin J. van den Bent, Mathilde C. M. Kouwenhoven, Johan M. Kros, Pieter Wesseling, Marion Smits
Summary: The T2-FLAIR mismatch sign is correlated with microcystic change in IDH-mutant astrocytomas, favorable prognosis, and Grade 2 tumors.
NEURO-ONCOLOGY ADVANCES
(2023)
