Discrete mitochondrial aberrations in the spinal cord of sporadic ALS patients

Mitochondrial dysfunction in glial cells: Implications for neuronal homeostasis and survival

(2017) Jordan Rose et al.   TOXICOLOGY

Riluzole But Not Melatonin Ameliorates Acute Motor Neuron Degeneration and Moderately Inhibits SOD1-Mediated Excitotoxicity Induced Disrupted Mitochondrial Ca2+ Signaling in Amyotrophic Lateral Sclerosis

(2017) Manoj Kumar Jaiswal   Frontiers in Cellular Neuroscience

Mitochondrial Dysfunction is a Converging Point of Multiple Pathological Pathways in Amyotrophic Lateral Sclerosis

(2017) Ping Shi et al.   JOURNAL OF ALZHEIMERS DISEASE

Age-associated physiological and pathological changes at the blood–brain barrier: A review

(2016) Franciska Erdő et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mitochondria and endoplasmic reticulum crosstalk in amyotrophic lateral sclerosis

(2016) Giovanni Manfredi et al.   NEUROBIOLOGY OF DISEASE

Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity

(2016) A.M. Bertholet et al.   NEUROBIOLOGY OF DISEASE

Myostatin inhibition therapy for insulin-deficient type 1 diabetes

(2016) Samantha K. Coleman et al.   Scientific Reports

Calorie restriction does not restore brain mitochondrial function in P301L tau mice, but it does decrease mitochondrial F0F1-ATPase activity

(2015) Vedad Delic et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Neuropathology of Amyotrophic Lateral Sclerosis and Its Variants

(2015) Shahram Saberi et al.   NEUROLOGIC CLINICS

Alterations of the blood-spinal cord barrier in sporadic amyotrophic lateral sclerosis

(2015) Shoichi Sasaki   NEUROPATHOLOGY

Ultrastructural studies of ALS mitochondria connect altered function and permeability with defects of mitophagy and mitochondriogenesis

(2015) Riccardo Ruffoli et al.   Frontiers in Cellular Neuroscience

Mitochondrial dynamism and the pathogenesis of Amyotrophic Lateral Sclerosis

(2015) Mauro Cozzolino et al.   Frontiers in Cellular Neuroscience

Role of mitochondria in mutant SOD1 linked amyotrophic lateral sclerosis

(2014) Wenzhi Tan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial Mechanisms in Cerebral Vascular Control: Shared Signaling Pathways with Preconditioning

(2014) David W. Busija et al.   JOURNAL OF VASCULAR RESEARCH

Mitochondrial Oxidative Phosphorylation Transcriptome Alterations in Human Amyotrophic Lateral Sclerosis Spinal Cord and Blood

(2014) Amy C. Ladd et al.   NEUROMOLECULAR MEDICINE

Blood-spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice

(2014) E. A. Winkler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysfunctional mitochondrial Ca2+ handling in mutant SOD1 mouse models of fALS: integration of findings from motor neuron somata and motor terminals

(2014) Ellen F. Barrett et al.   Frontiers in Cellular Neuroscience

Blood-CNS Barrier Impairment in ALS patients versus an animal model

(2014) Svitlana Garbuzova-Davis et al.   Frontiers in Cellular Neuroscience

The ER mitochondria calcium cycle and ER stress response as therapeutic targets in amyotrophic lateral sclerosis

(2014) Vedrana Tadic et al.   Frontiers in Cellular Neuroscience

Mitochondrial damage revealed by immunoselection for ALS-linked misfolded SOD1

(2013) S. Pickles et al.   HUMAN MOLECULAR GENETICS

Enhancing Mitochondrial Calcium Buffering Capacity Reduces Aggregation of Misfolded SOD1 and Motor Neuron Cell Death without Extending Survival in Mouse Models of Inherited Amyotrophic Lateral Sclerosis

(2013) P. A. Parone et al.   JOURNAL OF NEUROSCIENCE

Developmental-Like Bone Regeneration by Human Embryonic Stem Cell-Derived Mesenchymal Cells

(2013) Liisa T. Kuhn et al.   TISSUE ENGINEERING PART A

Neural Progenitors Derived From Human Induced Pluripotent Stem Cells Survive and Differentiate Upon Transplantation Into a Rat Model of Amyotrophic Lateral Sclerosis

(2013) Iuliana Ristea Popescu et al.   Stem Cells Translational Medicine

Impaired blood–brain/spinal cord barrier in ALS patients

(2012) Svitlana Garbuzova-Davis et al.   BRAIN RESEARCH

Spatial Parkin Translocation and Degradation of Damaged Mitochondria via Mitophagy in Live Cortical Neurons

(2012) Qian Cai et al.   CURRENT BIOLOGY

Mitochondrial Dynamics and Bioenergetic Dysfunction Is Associated with Synaptic Alterations in Mutant SOD1 Motor Neurons

(2012) J. Magrane et al.   JOURNAL OF NEUROSCIENCE

In Vivo Pathogenic Role of Mutant SOD1 Localized in the Mitochondrial Intermembrane Space

(2011) A. Igoudjil et al.   JOURNAL OF NEUROSCIENCE

Disruption of neurovascular unit prior to motor neuron degeneration in amyotrophic lateral sclerosis

(2011) Kazunori Miyazaki et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS

(2011) Mariely DeJesus-Hernandez et al.   NEURON

Mitochondrial dysfunction in ALS

(2011) Mauro Cozzolino et al.   PROGRESS IN NEUROBIOLOGY

Gray matter perfusion correlates with disease severity in ALS

(2010) R. R. Rule et al.   NEUROLOGY

Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS

(2010) Adrian Israelson et al.   NEURON

ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import

(2010) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional complementation of mitochondrial DNAs: Mobilizing mitochondrial genetics against dysfunction

(2009) Eric A. Schon et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Mitochondrial dysfunction in amyotrophic lateral sclerosis

(2009) Ping Shi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The mitochondrial permeability transition pore: A molecular target for amyotrophic lateral sclerosis therapy

(2009) Lee J. Martin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

(2009) C. Vance et al.   SCIENCE

Impaired mitochondria-dependent vasodilation in cerebral arteries of Zucker obese rats with insulin resistance

(2008) Prasad V. G. Katakam et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

High levels of Fis1, a pro-fission mitochondrial protein, trigger autophagy

(2008) Ligia C. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration

(2008) Zhihui Zhong et al.   NATURE NEUROSCIENCE

Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis

(2008) P Pinton et al.   ONCOGENE

TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

(2008) J. Sreedharan et al.   SCIENCE

Rapidly Increased Neuronal Mitochondrial Biogenesis After Hypoxic-Ischemic Brain Injury

(2008) Wei Yin et al.   STROKE

Gradients in the Liver's Extracellular Matrix Chemistry from Periportal to Pericentral Zones: Influence on Human Hepatic Progenitors

(2008) Randall McClelland et al.   TISSUE ENGINEERING PART A