Review
Clinical Neurology
Adnan Qureshi, Yasemin Akinci, Wei Huang, Muhammad F. Ishfaq, Ameer E. Hassan, Farhan Siddiq, Camilo R. Gomez
Summary: This study evaluated the cost-effectiveness of endovascular treatment (EVT) alone compared with EVT following intravenous (IV) recombinant tissue plasminogen activator (r-tPA) in patients with acute ischemic stroke (AIS). The results showed that EVT alone was more cost-effective than EVT and IV r-tPA combined treatment.
JOURNAL OF NEUROSURGERY
(2023)
Article
Clinical Neurology
Leon A. Rinkel, Kilian M. Treurniet, Daan Nieboer, Manon Kappelhof, Natalie E. LeCouffe, Agnetha A. E. Bruggeman, Wim H. van Zwam, Geert J. Lycklama a Nijeholt, Elyas Ghariq, Maarten Uyttenboogaart, Diederik W. J. Dippel, Yvo B. W. E. M. Roos, Jonathan M. Coutinho, Charles B. L. M. Majoie, Bart J. Emmer
Summary: This study aimed to evaluate the effect of intravenous alteplase treatment (IVT) on endovascular treatment (EVT) and found that the first-line EVT technique can modify the treatment effect of IVT. Patients treated with aspiration alone as the first-line technique had worse clinical outcomes if they did not receive IVT, while no such difference was observed in patients treated with stent retrievers.
Article
Medicine, General & Internal
Waranya Rattanavipapong, Thanaboon Worakijthamrongchai, Budsadee Soboon, Vilawan Luankongsomchit, Mananchaya Kongmuangpuk, Wanrudee Isaranuwatchai, Yot Teerawattananon, Yongchai Nilanont
Summary: EVT has been shown to be cost-effective in treating AIS patients in Thailand, both for those eligible for intravenous alteplase and those who are not.
Article
Clinical Neurology
Manon Kappelhof, Manon L. Tolhuisen, Kilian M. Treurniet, Bruna G. Dutra, Heitor Alves, Guang Zhang, Scott Brown, Keith W. Muir, Antoni Davalos, Yvo B. W. E. M. Roos, Jeffrey L. Saver, Andrew M. Demchuk, Tudor G. Jovin, Serge Bracard, Bruce C. Campbell, Aad van der Lugt, Francis Guillemin, Philip White, Michael D. Hill, Diederik W. J. Dippel, Peter J. Mitchell, Mayank Goyal, Henk A. Marquering, Charles B. L. M. Majoie
Summary: This study found that increased thrombus perviousness was associated with improved functional outcomes in patients with acute ischemic stroke. While control arm patients showed better outcomes with increased perviousness, there was no significant association in the EVT arm. Mortality and follow-up infarct volume decreased with higher thrombus attenuation increase in the overall population.
Review
Clinical Neurology
Aristeidis H. Katsanos, Guillaume Turc, Marios Psychogios, Johannes Kaesmacher, Lina Palaiodimou, Maria Ioanna Stefanou, George Magoufis, Ashkan Shoamanesh, Marios Themistocleous, Simona Sacco, Jens Fiehler, Jan Gralla, Daniel Strbian, Andrei Alexandrov, Urs Fischer, Georgios Tsivgoulis
Summary: This study compared the efficacy of direct endovascular treatment and bridging therapy for patients with acute large vessel occlusion. The results showed no significant differences in functional outcomes between the two treatment groups, but patients receiving direct endovascular treatment had a lower likelihood of successful recanalization compared to those receiving bridging therapy.
Review
Clinical Neurology
William K. Diprose, Michael T. M. Wang, Kaustubha Ghate, Stefan Brew, James R. Caldwell, Ben Mcguinness, P. Alan Barber
Summary: The meta-analysis concluded that adjunctive IAT with EVT does not show significant differences in terms of safety and efficacy compared to EVT alone, although there is a trend towards higher functional independence with EVT + IAT treatment.
Article
Clinical Neurology
Marie Louise E. Bernsen, Agnetha A. E. Bruggeman, Josje Brouwer, Bart J. Emmer, Charles B. L. M. Majoie, Jonathan M. Coutinho, Robert-Jan B. Goldhoorn, Robert J. van Oostenbrugge, Wim H. van Zwam, Christiaan van der Leij, Wouter J. Schonewille, Jasper M. Martens, Jeannette Hofmeijer
Summary: This study compares the effectiveness of first-line direct aspiration versus stent retriever thrombectomy for posterior circulation stroke. The findings suggest that first-line aspiration is associated with better reperfusion, shorter procedure time, and improved clinical outcomes compared to stent retriever thrombectomy in patients with ischemic stroke based on large vessel occlusion in the posterior circulation.
Article
Clinical Neurology
Seung-Jae Lee, Tae-Kyeong Lee, Bum-Tae Kim, Dong-Seong Shin
Summary: Thrombus migration (TM) occurs in about 19.5% of patients undergoing thrombectomy, with intravenous thrombolysis (IVT) and female sex being associated with TM. TM is also associated with better functional outcomes in patients, regardless of the angiographic outcomes.
WORLD NEUROSURGERY
(2021)
Review
Clinical Neurology
William K. Diprose, Michael T. M. Wang, Kaustubha Ghate, Stefan Brew, James R. Caldwell, Ben McGuinness, P. Alan Barber
Summary: Based on a systematic review and meta-analysis, adjunct intra-arterial thrombolysis (IAT) as a supplement to endovascular thrombectomy (EVT) appears to be safe and potentially effective in ischemic stroke patients.
Article
Clinical Neurology
Youngran Kim, Anjail Sharrief, Min Ji Kwak, Swapnil Khose, Rania Abdelkhaleq, Sergio Salazar-Marioni, Guo-Qiang Zhang, Sunil A. Sheth
Summary: This study examines the equity in access to and utilization of endovascular therapy (EVT) across racial and ethnic groups. The findings indicate that Black patients have lower rates of EVT compared to White patients, despite similar admissions to EVT-performing hospitals and comprehensive stroke centers.
Article
Clinical Neurology
Karim Mahawish, John Gommans, Timothy Kleinig, Bhavesh Lallu, Alicia Tyson, Annemarei Ranta
Summary: The switch from alteplase to tenecteplase for stroke thrombolysis was successfully implemented with stakeholder endorsement. Patients treated with tenecteplase showed better clinical outcomes, shorter door-to-needle time, and similar complication rates compared to alteplase.
Article
Neurosciences
Xiumei Guo, Yu Xiong, Xinyue Huang, Zhigang Pan, Xiaodong Kang, Chunhui Chen, Jianfeng Zhou, Cui'e Wang, Shu Lin, Weipeng Hu, Lingxing Wang, Feng Zheng
Summary: This study compared the safety and efficacy of aspiration and stent retriever in the treatment of posterior circulation stroke. The results showed that aspiration achieved better recanalization, first-pass effect, and shorter procedure time compared to stent retriever, suggesting that aspiration may be a safer option.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Clinical Neurology
Chu Chen, Tangqin Zhang, Youqing Xu, Xiangjun Xu, Junfeng Xu, Ke Yang, Lili Yuan, Qian Yang, Xianjun Huang, Zhiming Zhou
Summary: This study aimed to investigate the factors influencing the first-pass effect (FPE) in endovascular thrombectomy (EVT) for anterior circulation large vessel occlusion stroke (ALVOS). Through retrospective analysis of patients, it was found that higher clot burden score (CBS), truncal-type occlusion, and favorable anatomy of the internal carotid artery (ICA) were associated with achieving FPE. Regardless of modified FPE (mFPE) or true FPE (tFPE), FPE was significantly associated with improved clinical outcomes.
FRONTIERS IN NEUROLOGY
(2022)
Editorial Material
Neuroimaging
Areej Fageeh, Gil Zur, Ange Diouf, Daniel La Russa, Brian Drake, Marlise dos Santos, Katie Caron, Nicole Birch, Stephen Karwaski, Laurie Trussler, Elizabeth Miller, Tadeu Fantaneanu, Parizad Varghaei, Gregory Walker, Howard Lesiuk, Robert Fahed
Summary: Tandem occlusions refer to the simultaneous presence of an intracranial large vessel occlusion and extracranial carotid artery stenosis or occlusion, which poses a unique challenge for endovascular procedures. A new technique called START has been developed, allowing for the simultaneous treatment of both intracranial and extracranial lesions. We present a technical video explaining the steps of the START technique.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2023)
Article
Clinical Neurology
Mihir Khunte, Xiao Wu, Emily W. Avery, Dheeraj Gandhi, Seyedmehdi Payabvash, Charles Matouk, Jeremy J. Heit, Max Wintermark, Gregory W. Albers, Pina Sanelli, Ajay Malhotra
Summary: This study evaluates the cost-effectiveness of endovascular thrombectomy (EVT) for ischemic stroke patients based on collateral status. The results show that EVT treatment is cost-effective for patients with good collateral circulation, and even for those with poor collateral circulation. Therefore, patients should not be excluded from thrombectomy solely based on collateral status.
JOURNAL OF NEUROSURGERY
(2022)
Review
Rehabilitation
Claire Della Vecchia, Marie Viprey, Julie Haesebaert, Anne Termoz, Caroline Giroudon, Alexandra Dima, Gilles Rode, Marie Preau, Anne-Marie Schott
Summary: Personal factors, particularly psychological and psychosocial factors, are positively associated with post-stroke participation. Environmental factors, such as support, relationships, and positive attitudes towards patients, are major facilitators of participation, along with physical environment and accessibility to appropriate services. Most of these factors are modifiable and should be addressed to improve patient participation.
DISABILITY AND REHABILITATION
(2021)
Article
Clinical Neurology
M. Messiaen, A. Duba, C. Boulangeat, M. Boucekine, A. Bourbon, M. Viprey, P. Auquier, C. Lancon, L. Boyer, G. Fond
Summary: Despite indications of high rates of Bullying at the Work Place (BWP) in French hospitals, there has been no quantitative study conducted so far. This study found that 41.7% of young physicians in France have experienced BWP, and factors such as age, number of night shifts, and weekly work hours were associated with BWP. Obstetric gynecology, psychiatry, surgery, medical specialties, and low-quality initial training were identified as high-risk factors for BWP among medical students and young physicians.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2021)
Article
Neurosciences
M. Messiaen, A. Duba, C. Boulangeat, M. Boucekine, A. Bourbon, M. Viprey, P. Auquier, C. Lancon, L. Boyer, G. Fond
Summary: The study found that over ninety percent of young doctors have been exposed to hospital professional violence at least once, with nearly 42% experiencing moral harassment. The perpetrators of violence are mostly male, but female perpetrators are also reported by students. Victims include both male and female, with residents and young MDs reporting more negative outcomes compared to undergraduate medical students. However, the majority of victims did not report the incidents to authorities.
ENCEPHALE-REVUE DE PSYCHIATRIE CLINIQUE BIOLOGIQUE ET THERAPEUTIQUE
(2021)
Article
Clinical Neurology
Marie Viprey, Vanessa Pauly, Sebastien Salas, Karine Baumstarck, Veronica Orleans, Pierre-Michel Llorca, Christophe Lancon, Pascal Auquier, Laurent Boyer, Guillaume Fond
Summary: This study compared the end-of-life care received by schizophrenia patients with lung cancer to patients without severe mental disorders. Despite receiving more and earlier palliative care, schizophrenia patients were found to receive less high-intensity end-of-life care, such as chemotherapy and surgery, compared to controls. Further studies are needed to explore the optimal end-of-life care for patients with schizophrenia and lung cancer.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2021)
Article
Clinical Neurology
M. Barral, H. Rabier, A. Termoz, H. Serrier, C. Colin, J. Haesebaert, L. Derex, N. Nighoghossian, A-M Schott, M. Viprey
Summary: The study found that in the first year after a stroke, patients' productivity losses and informal care costs represent a significant economic burden for society, comparable to direct costs. These costs should be considered in economic evaluations to avoid underestimating the societal stroke economic burden.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Letter
Hematology
Celine Row, Pierre Chamouni, Claire Berger, Anne Lienhart, Sandrine Meunier, Mathilde Fretigny, Vincent Dalibard, Marie Viprey, Herve Chambost, Virginie Barbay, Julien Bovet
Article
Respiratory System
Isabelle Durieu, Faustine Dalon, Quitterie Reynaud, Lydie Lemonnier, Clemence Dehillotte, Marjorie Berard, Deborah Walther, Marie Viprey, Eric Van Ganse, Manon Belhassen
Summary: This study evaluated the impact of modified demographics and changes in cystic fibrosis (CF) management on resource consumption and the cost of care for CF patients. The study found a significant increase in the annual cost per CF patient between 2006 and 2017, mostly due to the introduction of cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapies.
JOURNAL OF CYSTIC FIBROSIS
(2022)
Article
Health Care Sciences & Services
Florence Sens, Marie Viprey, Vincent Piriou, Jean-Louis Peix, Eleonore Herquelot, Pauline Occelli, Stephanie Bourdy, Atul A. Gawande, Matthew J. Carty, Philippe Michel, Jean-Christophe Lifante, Cyrille Colin, Antoine Duclos
Summary: This study found that the way the checklist is executed in routine practice may reflect the teamwork and safety climate in the operating room. The presence of a fully completed checklist in medical records was associated with higher safety attitudes among teams. Compliance with checklists can be considered as an indicator of the extent of safety in operating room practice.
JOURNAL OF PATIENT SAFETY
(2022)
Article
Clinical Neurology
Florent Isnard, Anne Termoz, Julie Haesebaert, Marie Viprey, Karim Tazarourte, Estelle Bravant, Nathalie Perreton, Serkan Cakmak, Sylvie Meyran, Catherine Ossedat, Bruno Ducreux, Christelle Pidoux, Thomas Bony, Marion Douplat, Veronique Potinet, Alain Sigal, Laurent Derex, Norbert Nighoghossian, Anne-Marie Schott-Pethelaz, Laura Mechtouff
Summary: There was an increasing rate of adequate TIA management over a 10-year period in the Rhone county in France, mainly driven by a marked increase of vessel imaging within 24 hours of admission.
CEREBROVASCULAR DISEASES
(2022)
Review
Public, Environmental & Occupational Health
Marlene Papus, Alexandra L. Dima, Marie Viprey, Anne -Marie Schott, Marie Paule Schneider, Teddy Novais
Summary: This study systematically reviewed randomized controlled trials (RCTs) to assess the efficacy of Motivational Interviewing (MI) in supporting medication adherence in adults with chronic conditions. The review found that MI had a significant positive impact on medication adherence and other clinical outcomes. MI shows promise as an approach to support medication adherence in different clinical settings.
PATIENT EDUCATION AND COUNSELING
(2022)
Article
Medicine, General & Internal
Guillemette Lienhart, Beatrice Thivichon-Prince, Pierre Farge, Anne-Marie Schott-Pethelaz, Marc Chaneliere
Summary: This study presents an exploratory research protocol focusing on the perceptions and attitudes of health professionals towards children with early childhood caries (ECC) and their parents. Semistructured interviews will be conducted among medical and dental health professionals, and verbatim quotations obtained from audio transcriptions will be analysed to identify health professionals' perceptions of ECC and the influence of these perceptions on clinical care for these children.
Article
Public, Environmental & Occupational Health
Christine Rousset-Jablonski, Faustine Dalon, Quitterie Reynaud, Lydie Lemonnier, Clemence Dehillotte, Flore Jacoud, Marjorie Berard, Marie Viprey, Eric Van Ganse, Isabelle Durieu, Manon Belhassen
Summary: The incidence of cancer is higher in cystic fibrosis (CF) patients, especially those who have undergone lung transplantation. Specific follow-up, screening, and cancer prevention are necessary for CF patients with transplants.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Otorhinolaryngology
M. Fieux, F. Carsuzaa, M. Nourredine, M. Alexandru, C. Giroudon, S. Bartier, M. Legre, V. Favier, L. Fath
Summary: This systematic review evaluates the results of surgical and instrumental procedures in the treatment of chronic rhinitis. The findings suggest that these procedures can improve nasal symptom scores and quality of life in adult patients with poorly controlled chronic rhinitis.
EUROPEAN ANNALS OF OTORHINOLARYNGOLOGY-HEAD AND NECK DISEASES
(2023)
Meeting Abstract
Pharmacology & Pharmacy
Teddy Novais, Marlene Papus, Marie Viprey, Anne-Marie Schott, Marie P. Schneider, Alexandra L. Dima
INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
(2022)
