Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation
Authors
Keywords
A20, Bid, E3 ubiquitin ligase, Toll-like receptor 4, Ubiquitination
Journal
Journal of Neuroinflammation
Volume 15, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-05-02
DOI
10.1186/s12974-018-1143-3
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Inhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide
- (2015) Y. S. Lee et al. EMBO Molecular Medicine
- Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance
- (2015) Michael Murphy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The dual roles of immunity in ALS: Injury overrides protection
- (2015) Benjamin J. Murdock et al. NEUROBIOLOGY OF DISEASE
- The Myeloid Differentiation Factor 88 (MyD88) Is Required for CD4+ T Cell Effector Function in a Murine Model of Inflammatory Bowel Disease
- (2014) M. Fukata et al. JOURNAL OF IMMUNOLOGY
- A20 deficiency causes spontaneous neuroinflammation in mice
- (2014) Renata Guedes et al. Journal of Neuroinflammation
- Ubiquitination in disease pathogenesis and treatment
- (2014) Doris Popovic et al. NATURE MEDICINE
- The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes
- (2014) Hans-Georg König et al. NEUROBIOLOGY OF DISEASE
- Astrocytic A20 ameliorates experimental autoimmune encephalomyelitis by inhibiting NF-κB- and STAT1-dependent chemokine production in astrocytes
- (2013) Xu Wang et al. ACTA NEUROPATHOLOGICA
- The anti-inflammatory drug BAY 11-7082 suppresses the MyD88-dependent signalling network by targeting the ubiquitin system
- (2013) Sam Strickson et al. BIOCHEMICAL JOURNAL
- Ubiquitin in the immune system
- (2013) Julia Zinngrebe et al. EMBO REPORTS
- CD14 Mediates Toll-like Receptor 4 (TLR4) Endocytosis and Spleen Tyrosine Kinase (Syk) and Interferon Regulatory Transcription Factor 3 (IRF3) Activation in Epithelial Cells and Impairs Neutrophil Infiltration andPseudomonas aeruginosaKillingin Vivo
- (2013) Sanhita Roy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation
- (2013) Yichuan Xiao et al. NATURE MEDICINE
- Glia and epilepsy: excitability and inflammation
- (2013) Orrin Devinsky et al. TRENDS IN NEUROSCIENCES
- Toll-like receptor activation reveals developmental reorganization and unmasks responder subsets of microglia
- (2012) Jörg Scheffel et al. GLIA
- The role of TBK1 and IKKϵ in the expression and activation of Pellino 1
- (2011) Hilary Smith et al. BIOCHEMICAL JOURNAL
- TNFAIP3 Gene Polymorphisms Are Associated with Response to TNF Blockade in Psoriasis
- (2011) Trilokraj Tejasvi et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Non-apoptotic role of BID in inflammation and innate immunity
- (2011) Garabet Yeretssian et al. NATURE
- Traf6 and A20 differentially regulate TLR4-Induced autophagy by affecting the ubiquitination of Beclin 1
- (2010) Chong-Shan Shi et al. Autophagy
- Toll-like receptor (TLR) expression on CD4+ and CD8+ T-cells in patients chronically infected with hepatitis C virus
- (2010) Talia Hammond et al. CELLULAR IMMUNOLOGY
- Bid regulates the immunological profile of murine microglia and macrophages
- (2010) Lior Mayo et al. GLIA
- Regulation of inflammatory and antiviral signaling by A20
- (2010) Kislay Parvatiyar et al. MICROBES AND INFECTION
- Targeting Toll-like receptors: emerging therapeutics?
- (2010) Elizabeth J. Hennessy et al. NATURE REVIEWS DRUG DISCOVERY
- RING Domain E3 Ubiquitin Ligases
- (2009) Raymond J. Deshaies et al. Annual Review of Biochemistry
- The TAK1-JNK cascade is required for IRF3 function in the innate immune response
- (2009) Bianhong Zhang et al. CELL RESEARCH
- Nonproteolytic Functions of Ubiquitin in Cell Signaling
- (2009) Zhijian J. Chen et al. MOLECULAR CELL
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
- (2009) Jean-Charles Lambert et al. NATURE GENETICS
- Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines
- (2009) Ping-Hui Tseng et al. NATURE IMMUNOLOGY
- Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production
- (2009) Mikyoung Chang et al. NATURE IMMUNOLOGY
- Breaking the chains: structure and function of the deubiquitinases
- (2009) David Komander et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Identification of the phosphorylation sites on the E3 ubiquitin ligase Pellino that are critical for activation by IRAK1 and IRAK4
- (2009) H. Smith et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Signaling to NF- B: Regulation by Ubiquitination
- (2009) I. E. Wertz et al. Cold Spring Harbor Perspectives in Biology
- Structural basis and specificity of human otubain 1-mediated deubiquitination
- (2008) Mariola J. Edelmann et al. BIOCHEMICAL JOURNAL
- Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series
- (2008) Fumiyo Ikeda et al. EMBO REPORTS
- The Ubiquitin-Editing Enzyme A20 Restricts Nucleotide-Binding Oligomerization Domain Containing 2-Triggered Signals
- (2008) Osamu Hitotsumatsu et al. IMMUNITY
- Toll-like receptor 4-dependent upregulation of cytokines in a transgenic mouse model of Alzheimer's disease
- (2008) Jing-Ji Jin et al. Journal of Neuroinflammation
- Microglial Dysfunction and Defective -Amyloid Clearance Pathways in Aging Alzheimer's Disease Mice
- (2008) S. E. Hickman et al. JOURNAL OF NEUROSCIENCE
- Lys63-Linked Polyubiquitination of IRAK-1 Is Required for Interleukin-1 Receptor- and Toll-Like Receptor-Mediated NF- B Activation
- (2008) D. B. Conze et al. MOLECULAR AND CELLULAR BIOLOGY
- Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus
- (2008) Stacy L Musone et al. NATURE GENETICS
- TRAF6 Autoubiquitination-Independent Activation of the NFκB and MAPK Pathways in Response to IL-1 and RANKL
- (2008) Matthew C. Walsh et al. PLoS One
- How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
- (2008) Jerry E. Chipuk et al. TRENDS IN CELL BIOLOGY
- The Pellino family: IRAK E3 ligases with emerging roles in innate immune signalling
- (2008) Paul N. Moynagh TRENDS IN IMMUNOLOGY
- The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1
- (2007) Alban Ordureau et al. BIOCHEMICAL JOURNAL
- Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20
- (2007) Su-Chang Lin et al. JOURNAL OF MOLECULAR BIOLOGY
- Screening of innate immune receptors in neurodegenerative diseases: A similar pattern
- (2007) Maryse Letiembre et al. NEUROBIOLOGY OF AGING
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started