PM2.5 exposure aggravates oligomeric amyloid beta-induced neuronal injury and promotes NLRP3 inflammasome activation in an in vitro model of Alzheimer’s disease

The mechanisms of air pollution and particulate matter in cardiovascular diseases

(2017) Antonella Fiordelisi et al.   HEART FAILURE REVIEWS

Particulate matter (PM 2.5 ) exposure season-dependently induces neuronal apoptosis and synaptic injuries

(2017) Minjun Chen et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

N -methyl- d -aspartate receptor-mediated calcium overload and endoplasmic reticulum stress are involved in interleukin-1beta-induced neuronal apoptosis in rat hippocampus

(2017) Yilong Dong et al.   JOURNAL OF NEUROIMMUNOLOGY

Role of oxidative stress and DNA hydroxymethylation in the neurotoxicity of fine particulate matter

(2017) Hongying Wei et al.   TOXICOLOGY

Analysis of PM 2.5 -induced cytotoxicity in human HaCaT cells based on a microfluidic system

(2017) Yuxiao Zhang et al.   TOXICOLOGY IN VITRO

Direct effects of airborne PM2.5 exposure on macrophage polarizations

(2016) Qingjie Zhao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Amelioration of particulate matter-induced oxidative damage by vitamin c and quercetin in human bronchial epithelial cells

(2016) Xiaoting Jin et al.   CHEMOSPHERE

The health effects of ambient PM2.5 and potential mechanisms

(2016) Shaolong Feng et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Gene-environment interactions linking air pollution and inflammation in Parkinson's disease

(2016) Pei-Chen Lee et al.   ENVIRONMENTAL RESEARCH

Mechanism and Regulation of NLRP3 Inflammasome Activation

(2016) Yuan He et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Nucleotide-Binding Domain, Leucine-Rich Repeat Protein 3 Inflammasome/IL-1 Receptor I Axis Mediates Innate, but Not Adaptive, Immune Responses after Exposure to Particulate Matter under 10 μm

(2015) Jeremy A. Hirota et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Progression and inflammation of human myeloid leukemia induced by ambient PM2.5 exposure

(2015) Xiao-Ting Jin et al.   ARCHIVES OF TOXICOLOGY

Role of Environmental Contaminants in the Etiology of Alzheimer’s Disease: A Review

(2015) Manivannan Yegambaram et al.   Current Alzheimer Research

NLRP3 inflammasome: From a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases

(2015) Amna Abderrazak et al.   Redox Biology

A Pilot Study to Assess Effects of Long-Term Inhalation of Airborne Particulate Matter on Early Alzheimer-Like Changes in the Mouse Brain

(2015) Dhaval P. Bhatt et al.   PLoS One

Air pollution and your brain: what do you need to know right now

(2014) Lilian Calderón-Garcidueñas et al.   Primary Health Care Research and Development

Antiepileptics Topiramate and Levetiracetam Alleviate Behavioral Deficits and Reduce Neuropathology in APPswe/PS1dE9 Transgenic Mice

(2013) Jian-Quan Shi et al.   CNS Neuroscience & Therapeutics

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

(2013) Ana Griciuc et al.   NEURON

Exposure to inhaled particulate matter activates early markers of oxidative stress, inflammation and unfolded protein response in rat striatum

(2013) R. Guerra et al.   TOXICOLOGY LETTERS

Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer’s disease

(2013) B Parajuli et al.   Cell Death & Disease

The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter

(2012) Jeremy A. Hirota et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

Short amyloid-beta immunogens show strong immunogenicity and avoid stimulating pro-inflammatory pathways in bone marrow-derived dendritic cells from C57BL/6J mice in vitro

(2011) Jian-Quan Shi et al.   PEPTIDES

Microglia Activated with the Toll-Like Receptor 9 Ligand CpG Attenuate Oligomeric Amyloid β Neurotoxicity in in Vitro and in Vivo Models of Alzheimer’s Disease

(2009) Yukiko Doi et al.   AMERICAN JOURNAL OF PATHOLOGY

Particulate Matter Induced Enhancement of Inflammatory Markers in the Brains of Apolipoprotein E Knockout Mice

(2009) Arezoo Campbell et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Differential requirement for the activation of the inflammasome for processing and release of IL-1  in monocytes and macrophages

(2008) M. G. Netea et al.   BLOOD

Role of Oxidant Stress on AT1 Receptor Expression in Neurons of Rabbits With Heart Failure and in Cultured Neurons

(2008) Dongmei Liu et al.   CIRCULATION RESEARCH

Air Pollution and Public Health: A Guidance Document for Risk Managers

(2008) Lorraine Craig et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

ATP is released by monocytes stimulated with pathogen-sensing receptor ligands and induces IL-1  and IL-18 secretion in an autocrine way

(2008) A. Piccini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA