Molecular regulation of follicle-stimulating hormone synthesis, secretion and action

Transcriptional regulation of follicle-stimulating hormone β-subunit in marmoset by an alternate distal promoter

(2017) Susha S. Kutteyil et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Genome-wide interactions between FSH and insulin-like growth factors in the regulation of human granulosa cell differentiation

(2017) Carlos Stocco et al.   HUMAN REPRODUCTION

Mitogen- and stress-activated protein kinase 1 is required for gonadotropin-releasing hormone–mediated activation of gonadotropin α-subunit expression

(2017) Majd Haj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Follicle-Stimulating Hormone β-Subunit Potentiates Bone Morphogenetic Protein 9-Induced Osteogenic Differentiation in Mouse Embryonic Fibroblasts

(2017) Xiao-Ya Su et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Blocking FSH induces thermogenic adipose tissue and reduces body fat

(2017) Peng Liu et al.   NATURE

Estradiol Restrains Prepubertal Gonadotropin Secretion in Female Mice via Activation of ERα in Kisspeptin Neurons

(2016) Sharon L. Dubois et al.   ENDOCRINOLOGY

Adrenocorticotropic hormone elicits gonadotropin secretion in premenopausal women

(2016) Jurate Aleknaviciute et al.   HUMAN REPRODUCTION

Follicle-Stimulating Hormone (FSH)-dependent Regulation of Extracellular Regulated Kinase (ERK) Phosphorylation by the Mitogen-activated Protein (MAP) Kinase Phosphatase MKP3

(2016) Elyse M. Donaubauer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SMAD3 Regulates Follicle-stimulating Hormone Synthesis by Pituitary Gonadotrope Cellsin Vivo

(2016) Yining Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Expression of FSH Receptor in Endometriotic Lesions

(2016) Donata Ponikwicka-Tyszko et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Long-chain unsaturated fatty acids reduce the transcriptional activity of the rat follicle-stimulating hormone β-subunit gene

(2016) Ryutaro MORIYAMA et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

A human FSHB transgene encoding the double N-glycosylation mutant (Asn7Δ Asn24Δ) FSHβ subunit fails to rescue Fshb null mice

(2016) Huizhen Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Forkhead box O member FOXO1 regulates the majority of follicle-stimulating hormone responsive genes in ovarian granulosa cells

(2016) Maria K. Herndon et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Evaluation of in vivo bioactivities of recombinant hypo- (FSH 21/18 ) and fully- (FSH 24 ) glycosylated human FSH glycoforms in Fshb null mice

(2016) Huizhen Wang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

GnRH Pulse Frequency Control ofFshbGene Expression Is Mediated via ERK1/2 Regulation of ICER

(2016) Iain R. Thompson et al.   MOLECULAR ENDOCRINOLOGY

Effects of intracerebroventricular infusions of ghrelin on secretion of follicle-stimulating hormone in peripubertal female sheep

(2016) Anna W�jcik-Gładysz et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

A regulatory loop between miR-132 and miR-125b involved in gonadotrope cells desensitization to GnRH

(2016) Jérôme Lannes et al.   Scientific Reports

Revisiting the expression and function of follicle-stimulation hormone receptor in human umbilical vein endothelial cells

(2016) Joanna Stelmaszewska et al.   Scientific Reports

Msx1 homeodomain transcription factor and TATA-binding protein interact to repress the expression of the glycoprotein hormone α subunit gene

(2015) Ki-Sun Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Follicle-Stimulating Hormone Increases Gap Junctional Communication Between Somatic and Germ-Line Follicular Compartments During Murine Oogenesis1

(2015) Stephany El-Hayek et al.   BIOLOGY OF REPRODUCTION

DS1, a Delta Subunit-Containing GABAA Receptor Agonist, Increases Gonadotropin Subunit Gene Expression in Mouse Pituitary Gonadotrophs1

(2015) Tselmeg Mijiddorj et al.   BIOLOGY OF REPRODUCTION

Prostate cancer imaging of FSHR antagonist modified with a hydrophilic linker

(2015) Chen Zhu et al.   Contrast Media & Molecular Imaging

β-Catenin Stabilization in Gonadotropes Impairs FSH Synthesis in Male Mice In Vivo

(2015) Derek Boerboom et al.   ENDOCRINOLOGY

GnRH Regulates Gonadotropin Gene Expression Through NADPH/Dual Oxidase-Derived Reactive Oxygen Species

(2015) Taeshin Kim et al.   ENDOCRINOLOGY

Hypoglycosylated hFSH Has Greater Bioactivity Than Fully Glycosylated Recombinant hFSH in Human Granulosa Cells

(2015) Chao Jiang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

FSH Regulates IGF-2 Expression in Human Granulosa Cells in an AKT-Dependent Manner

(2015) Sarah C. Baumgarten et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Production, purification, and characterization of recombinant hFSH glycoforms for functional studies

(2015) Viktor Y. Butnev et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Homeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development

(2015) Huimin Xie et al.   MOLECULAR ENDOCRINOLOGY

Rapid Communication: A MicroRNA-132/212 Pathway Mediates GnRH Activation of FSH Expression

(2015) Jérôme Lannes et al.   MOLECULAR ENDOCRINOLOGY

Follicle-Stimulating Hormone

(2015) Johan Smitz et al.   Reproductive Sciences

Sex-specific regulation of follicle-stimulating hormone secretion by synaptotagmin 9

(2015) Lindsey K. Roper et al.   Nature Communications

Adiponectin expression in the porcine pituitary during the estrous cycle and its effect on LH and FSH secretion

(2014) Marta Kiezun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

FSH Receptor (FSHR) Expression in Human Extragonadal Reproductive Tissues and the Developing Placenta, and the Impact of Its Deletion on Pregnancy in Mice1

(2014) Julie A.W. Stilley et al.   BIOLOGY OF REPRODUCTION

Bone Morphogenetic Protein 2 Stimulates Noncanonical SMAD2/3 Signaling via the BMP Type 1A Receptor in Gonadotrope-Like Cells: Implications for FSH Synthesis

(2014) Ying Wang et al.   ENDOCRINOLOGY

Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2

(2014) Jérôme Fortin et al.   FASEB JOURNAL

Gonadotrope-specific Deletion ofDicerResults in Severely Suppressed Gonadotropins and Fertility Defects

(2014) Huizhen Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling Through FSH Receptors on Human Umbilical Vein Endothelial Cells Promotes Angiogenesis

(2014) Julie A. Stilley et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Pituitary Gonadotrophic Hormone Synthesis, Secretion, Subunit Gene Expression and Cell Structure in Normal and Follicle-Stimulating Hormone β Knockout, Follicle-Stimulating Hormone Receptor Knockout, Luteinising Hormone Receptor Knockout, Hypogonadal and

(2014) M. H. Abel et al.   JOURNAL OF NEUROENDOCRINOLOGY

Homer1 Alternative Splicing Is Regulated by Gonadotropin-Releasing Hormone and Modulates Gonadotropin Gene Expression

(2014) Q. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Effect of orexin A on the release of GnRH-stimulated gonadotrophins from cultured pituitary cells of immature and mature female rats

(2014) L. Martynska et al.   NEUROPEPTIDES

Redirecting intracellular trafficking and the secretion pattern of FSH dramatically enhances ovarian function in mice

(2014) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Follicle-stimulating hormone regulates expression and activity of epidermal growth factor receptor in the murine ovarian follicle

(2014) Stephany El-Hayek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanisms of Activin-Stimulated FSH Synthesis: The Story of a Pig and a FOX1

(2013) Daniel J. Bernard et al.   BIOLOGY OF REPRODUCTION

Expression of follicle-stimulating hormone receptor by the vascular endothelium in tumor metastases

(2013) Ahsan Siraj et al.   BMC CANCER

Gonadotropins regulate ovarian germ cell mitosis/meiosis decision in the embryonic chicken

(2013) Bin He et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hypo-glycosylated human follicle-stimulating hormone (hFSH21/18) is much more active in vitro than fully-glycosylated hFSH (hFSH24)

(2013) George R. Bousfield et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Msx1 Homeodomain Protein Represses the αGSU and GnRH Receptor Genes During Gonadotrope Development

(2013) Huimin Xie et al.   MOLECULAR ENDOCRINOLOGY

Impaired Fertility and FSH Synthesis in Gonadotrope-SpecificFoxl2Knockout Mice

(2013) Stella Tran et al.   MOLECULAR ENDOCRINOLOGY

IGF-I Signaling Is Essential for FSH Stimulation of AKT and Steroidogenic Genes in Granulosa Cells

(2013) Ping Zhou et al.   MOLECULAR ENDOCRINOLOGY

Research Resource: Small RNA-seq of Human Granulosa Cells Reveals miRNAs in FSHR and Aromatase Genes

(2013) Agne Velthut-Meikas et al.   MOLECULAR ENDOCRINOLOGY

Differentially Expressed miRNAs after GnRH Treatment and Their Potential Roles in FSH Regulation in Porcine Anterior Pituitary Cell

(2013) Rui-Song Ye et al.   PLoS One

Dynamic changes in glycosylation and glycan composition of serum FSH and LH during natural ovarian stimulation

(2013) Leif Wide et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Activin A induction of murine and ovine follicle-stimulating hormone β transcription is SMAD-dependent and TAK1 (MAP3K7)/p38 MAPK-independent in gonadotrope-like cells

(2012) Ying Wang et al.   CELLULAR SIGNALLING

Neuroendocrine control of female reproductive function by the activin receptor ALK7

(2012) Tatiana Sandoval-Guzmán et al.   FASEB JOURNAL

miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation

(2012) X Lin et al.   LEUKEMIA

The glycan structure in recombinant human FSH affects endocrine activity and global gene expression in human granulosa cells

(2012) Nazareth Loreti et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

GnRH Regulation ofJunandAtf3Requires Calcium, Calcineurin, and NFAT

(2012) April K. Binder et al.   MOLECULAR ENDOCRINOLOGY

GnRH Increases c-Fos Half-Life Contributing to Higher FSHβ Induction

(2012) Gaddameedi R. Reddy et al.   MOLECULAR ENDOCRINOLOGY

The Adapter Protein APPL1 Links FSH Receptor to Inositol 1,4,5-Trisphosphate Production and Is Implicated in Intracellular Ca2+Mobilization

(2011) Richard M. Thomas et al.   ENDOCRINOLOGY

Impaired FSHβ Expression in the Pituitaries ofFoxl2Mutant Animals

(2011) Nicholas J. Justice et al.   MOLECULAR ENDOCRINOLOGY

Characterization of a MAPK Scaffolding Protein Logic Gate in Gonadotropes

(2011) Soon Gang Choi et al.   MOLECULAR ENDOCRINOLOGY

Synthesis and secretion of gonadotropins including structure-function correlates

(2011) George R. Bousfield et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Mapping the follicle-stimulating hormone-induced signaling networks

(2011) Pauline Gloaguen   Frontiers in Endocrinology

FSH-receptor isoforms and FSH-dependent gene transcription in human monocytes and osteoclasts

(2010) Lisa J. Robinson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Follicle-stimulating hormone promotes RANK expression on human monocytes

(2010) Joseph G. Cannon et al.   CYTOKINE

Female Mice Expressing Constitutively Active Mutants of FSH Receptor Present with a Phenotype of Premature Follicle Depletion and Estrogen Excess

(2010) Hellevi Peltoketo et al.   ENDOCRINOLOGY

FSH Aggravates Periodontitis-related Bone Loss in Ovariectomized Rats

(2010) S. Liu et al.   JOURNAL OF DENTAL RESEARCH

Emerging roles for the FSH receptor adapter protein APPL1 and overlap of a putative 14-3-3τ interaction domain with a canonical G-protein interaction site

(2010) James A. Dias et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Immunoneutralization of Inhibin in Cycling Rats Increases Follicle-Stimulating Hormone Secretion, Stimulates the Ovary and Attenuates Progesterone Receptor-Dependent Preovulatory Luteinizing Hormone Secretion

(2010) Ana Gordon et al.   NEUROENDOCRINOLOGY

Expression of Follicle-Stimulating Hormone Receptor in Tumor Blood Vessels

(2010) Aurelian Radu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Therapeutic potential of β-arrestin- and G protein-biased agonists

(2010) Erin J. Whalen et al.   TRENDS IN MOLECULAR MEDICINE

Cotranslational and Posttranslational N-Glycosylation of Polypeptides by Distinct Mammalian OST Isoforms

(2009) Catalina Ruiz-Canada et al.   CELL

A network of miRNAs expressed in the ovary are regulated by FSH

(2009) Nan Yao   Frontiers in Bioscience-Landmark

Frequency-Dependent Regulation of Follicle-Stimulating Hormone   by Pulsatile Gonadotropin-Releasing Hormone Is Mediated by Functional Antagonism of bZIP Transcription Factors

(2009) N. A. Ciccone et al.   MOLECULAR AND CELLULAR BIOLOGY

Hormonal regulation of pituitary FSH sialylation in male rats

(2009) V. Ambao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Follicle-stimulating hormone isoforms and plasma concentrations of estradiol and inhibin A in dairy cows with ovulatory and non-ovulatory follicles during the first postpartum follicle wave

(2008) Stephen T. Butler et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Paired-Like Homeodomain Transcription Factors 1 and 2 Regulate Follicle-Stimulating Hormone β-Subunit Transcription through a Conservedcis-Element

(2008) Pankaj Lamba et al.   ENDOCRINOLOGY

Activator Protein-1 and Smad Proteins Synergistically Regulate Human Follicle-Stimulating Hormone β-Promoter Activity

(2008) Ying Wang et al.   ENDOCRINOLOGY

Occurrence of postmenopausal-like acidic follicle-stimulating hormone (FSH) isoforms precedes the rise of FSH before menopause

(2008) Chris M.G. Thomas et al.   FERTILITY AND STERILITY

Signaling by G-protein-coupled receptor (GPCR): Studies on the GnRH receptor

(2008) Zvi Naor   FRONTIERS IN NEUROENDOCRINOLOGY

Bone morphogenetic protein-4 interacts with activin and GnRH to modulate gonadotrophin secretion in LβT2 gonadotrophs

(2008) L Nicol et al.   JOURNAL OF ENDOCRINOLOGY

A Composite Element that Binds Basic Helix Loop Helix and Basic Leucine Zipper Transcription Factors Is Important for Gonadotropin-Releasing Hormone Regulation of the Follicle-Stimulating Hormone β Gene

(2008) Nick A. Ciccone et al.   MOLECULAR ENDOCRINOLOGY

Oocyte-specific deletion of complex and hybrid N-glycans leads to defects in preovulatory follicle and cumulus mass development

(2008) Suzannah A Williams et al.   REPRODUCTION

Progesterone and the distribution of pituitary gonadotropin isoforms in cattle

(2007) G. Perera-Marín et al.   ANIMAL REPRODUCTION SCIENCE