Ferutinin Induces Membrane Depolarization, Permeability Transition Pore Formation, and Respiration Uncoupling in Isolated Rat Liver Mitochondria by Stimulation of Ca2+-Permeability

New Drugs from Old Natural Compounds: Scarcely Investigated Sesquiterpenes as New Possible Therapeutic Agents

(2018) Stefania Sut et al.   CURRENT MEDICINAL CHEMISTRY

Calcium-Induced Mitochondrial Permeability Transitions: Parameters of Ca2+ Ion Interactions with Mitochondria and Effects of Oxidative Agents

(2017) Nina G. Golovach et al.   JOURNAL OF MEMBRANE BIOLOGY

To involvement the conformation of the adenine nucleotide translocase in opening the Tl+-induced permeability transition pore in Ca2+-loaded rat liver mitochondria

(2016) Sergey M. Korotkov et al.   TOXICOLOGY IN VITRO

Polyphenols as mitochondria-targeted anticancer drugs

(2015) Sylwia Gorlach et al.   CANCER LETTERS

Hemisynthesis, Antitumoral Effect, and Molecular Docking Studies of Ferutinin and Its Analogues

(2015) Rémi Safi et al.   Chemical Biology & Drug Design

Ferutinin as a Ca2+ complexone: lipid bilayers, conductometry, FT-IR, NMR studies and DFT-B3LYP calculations

(2015) A. Dubis et al.   DALTON TRANSACTIONS

Critical-size bone defect repair using amniotic fluid stem cell/collagen constructs: Effect of oral ferutinin treatment in rats

(2015) Manuela Zavatti et al.   LIFE SCIENCES

Cell death disguised: The mitochondrial permeability transition pore as the c-subunit of the F1FO ATP synthase

(2015) Elizabeth A. Jonas et al.   PHARMACOLOGICAL RESEARCH

Ferutinin, an Apoptosis Inducing Terpenoid from Ferula ovina

(2014) Maryam Moghaddam Matin et al.   Asian Pacific Journal of Cancer Prevention

Plant natural products: from traditional compounds to new emerging drugs in cancer therapy

(2014) L. Ouyang et al.   CELL PROLIFERATION

Mitochondrial Permeability Transition as Target of Anticancer Drugs

(2014) Lisa Via et al.   CURRENT PHARMACEUTICAL DESIGN

Investigating anticancer properties of the sesquiterpene ferutinin on colon carcinoma cells, in vitro and in vivo

(2014) Nahid Arghiani et al.   LIFE SCIENCES

SLC25A23 augments mitochondrial Ca2+ uptake, interacts with MCU, and induces oxidative stress–mediated cell death

(2014) Nicholas E. Hoffman et al.   MOLECULAR BIOLOGY OF THE CELL

Calcium mobilization by the plant estrogen ferutinin does not induce blood platelet aggregation

(2014) Maria Zamaraeva et al.   Pharmacological Reports

Ferutinin Induces in Vitro Eryptosis/Erythroptosis in Human Erythrocytes through Membrane Permeabilization and Calcium Influx

(2013) Minghui Gao et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oxidative damage of rat liver mitochondria during exposure to t-butyl hydroperoxide. Role of Ca2+ ions in oxidative processes

(2013) Ilya B. Zavodnik et al.   LIFE SCIENCES

Natural Products: Promising Resources for Cancer Drug Discovery

(2012) Susmita Mondal et al.   Anti-Cancer Agents in Medicinal Chemistry

Natural daucane sesquiterpenes with antiproliferative and proapoptotic activity against human tumor cells

(2011) Stefano Dall’Acqua et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Influence of Tl+ on mitochondrial permeability transition pore in Ca2+-loaded rat liver mitochondria

(2011) Sergey M. Korotkov et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Structural and histomorphometric evaluations of ferutinin effects on the uterus of ovariectomized rats during osteoporosis treatment

(2011) Marzia Ferretti et al.   LIFE SCIENCES

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

(2011) Joshua M. Baughman et al.   NATURE

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

(2011) Diego De Stefani et al.   NATURE

The mitochondrial permeability transition from yeast to mammals

(2010) Luca Azzolin et al.   FEBS LETTERS

Antiinflammatory sesquiterpenes from the root oil ofFerula hermonis

(2010) Afaf Geroushi et al.   PHYTOTHERAPY RESEARCH

Modulation of Apoptosis by Natural Products for Cancer Therapy

(2010) Simone Fulda   PLANTA MEDICA