Review
Biochemistry & Molecular Biology
Mirian Pateiro, Julian Andres Gomez-Salazar, Mariana Jaime-Patlan, Maria Elena Sosa-Morales, Jose M. Lorenzo
Summary: Plants are rich in bioactive compounds such as polyphenols, which can replace synthetic antioxidants in meat products. These natural antioxidants, obtained from fruits, vegetables, herbs, and spices, contribute to the quality of meat products and offer benefits in terms of environmental protection and resource reutilization.
Review
Biochemistry & Molecular Biology
Eyana Thomas, Laura E. Stewart, Brien A. Darley, Ashley M. Pham, Isabella Esteban, Siva S. Panda
Summary: Viral infections are complex medical issues that pose a threat to the economy and global health. Natural products from plant sources, known for their diversity, have been a major inspiration for new drug development, yet they have received little attention from large pharmaceutical industries.
Article
Green & Sustainable Science & Technology
Shahid Adeel, Maryam Habiba, Shumaila Kiran, Sarosh Iqbal, Shazia Abrar, Ch Moazzam Hassan
Summary: This study evaluated the antioxidant and sun protection effects of apple, banana, and orange peel extracts in skincare formulations. The extracts containing polyphenols showed antioxidant activity and were incorporated into stable cosmetic emulsions. The fruit peel waste could serve as a sustainable source of natural antioxidants for the personal care industry.
Review
Pharmacology & Pharmacy
Giovane de Jesus Gomes Ribeiro, Sun Liu Rei Yan, Giuseppe Palmisano, Carsten Wrenger
Summary: Malaria, mainly affecting Africa and Southeast Asia, claims over 500,000 lives annually. The disease is caused by the protozoan parasite Plasmodium, with Plasmodium vivax and Plasmodium falciparum being the main culprits in humans. The emergence of artemisinin-resistant strains in Southeast Asia underscores the urgent need for more effective and safe antimalarial drugs. This mini-review explores the potential of plant extracts and isolated natural products as antimalarial agents, focusing on in vitro studies conducted in the last five years (2018-2022).
Editorial Material
Biochemistry & Molecular Biology
Thomas Andrillon
Summary: This passage discusses the relationship between sleep depth and brain waves, pointing out that both slow wave sleep and rapid eye movement sleep have an impact on sleep depth.
Article
Food Science & Technology
Bingwei He, Yueyue Chen, Shishuai Yu, Yining Hao, Feifei Wang, Liping Qu
Summary: Chronic sleep deficiency increases the risk of physical and mental disorders and may cause unpleasant experiences in daily life. Sleep-associated skin diseases have drawn public attention. Health food developed for skincare via improving sleep quality has positive effects.
Article
Clinical Neurology
Michael L. Perlis, Knashawn H. Morales, Ivan Vargas, Donn A. Posner, Michael A. Grandner, Alexandria L. Muench, Mark W. Seewald, Nalaka S. Gooneratne, Jacqueline D. Kloss, Amy M. Gencarelli, Waliuddin S. Khader, Michael E. Thase, Jason G. Ellis
Summary: Longitudinal analysis of subjects transitioning from acute insomnia (AI) to chronic insomnia showed that the process may not necessarily involve sleep extension, and could occur before 3 months of experiencing disrupted sleep continuity for >=3 nights. A significant proportion of subjects failed to recover from acute insomnia or develop chronic insomnia after acute insomnia.
JOURNAL OF SLEEP RESEARCH
(2021)
Article
Plant Sciences
Carolina P. Reyes, Samuel Rodriguez Sabina, Rocio Lopez-Cabeza, Cristina G. Montelongo, Cristina Gimenez, Ignacio A. Jimenez, Raimundo Cabrera, Isabel L. Bazzochi
Summary: Phytopathogens cause significant losses in agriculture. This study evaluated sixteen plant species from the Canary Islands against three phytopathogenic fungi and identified five potential candidates for biofungicide development.
Review
Biotechnology & Applied Microbiology
Junjie Lin, Xue Yin, Youran Zeng, Xinyu Hong, Shuncang Zhang, Beimi Cui, Qinlong Zhu, Zongsuo Liang, Zheyong Xue, Dongfeng Yang
Summary: Plant-derived natural products have various applications and the use of synthetic biology and plant chassis for their synthesis has become a significant trend. This paper presents recent progress in synthesizing different types of plant natural products using plant chassis and summarizes the four primary types of plant chassis as well as the enabling technologies in synthetic biology development. The role of different optimization strategies in breaking the upper limit of natural product production in plant chassis is also discussed.
BIOTECHNOLOGY ADVANCES
(2023)
Review
Agriculture, Dairy & Animal Science
Yongmei Guo, Li Li, Sumei Yan, Binlin Shi
Summary: Climate change and heat stress present significant challenges for the dairy industry, but plant extracts can play an important role in alleviating heat stress in dairy cows.
Article
Plant Sciences
Hesham R. El-Seedi, Shaden A. M. Khalifa, Azza H. Mohamed, Nermeen Yosri, Chao Zhao, Nabil El-Wakeil, Nour F. Attia, Baojun Xu, AbdElhafez R. AbdElhafez, Mohammad H. Boskabady, Sherif Elseedy, Thomas Efferth, Rob Verpoorte
Summary: Schistosomiasis is a water-borne disease caused by blood flukes, mainly affecting people in low-income regions. Plants have potential as alternative molluscicides and medicines to treat the disease, while also providing income for farmers.
PHYTOCHEMISTRY REVIEWS
(2022)
Review
Biochemistry & Molecular Biology
Li Ma, Mengmeng Zhang, Rong Zhao, Dan Wang, Yuerong Ma, Li Ai
Summary: Cancer is a major threat to human health and safety, with a lack of safe and effective therapeutic drugs. Intervening and preventing in the premalignant process is an effective way to reverse carcinogenesis. Plant natural products are promising sources for cancer chemoprevention due to their richness in sources.
Review
Chemistry, Multidisciplinary
Gina Porras, Francois Chassagne, James T. Lyles, Lewis Marquez, Micah Dettweiler, Akram M. Salam, Tharanga Samarakoon, Sarah Shabih, Darya Raschid Farrokhi, Cassandra L. Quave
Summary: The crisis of antibiotic resistance highlights the importance of exploring plant natural products as a potential source of antibacterial compounds. This review systematically examines the antibacterial activity of 459 plant-derived compounds, with a focus on 183 compounds that show promising potential as antibiotics. The rich chemodiversity and clinical effectiveness of plant NPs make them a valuable resource for future antibiotic discovery and development efforts.
Article
Biochemistry & Molecular Biology
Aikaterini Kandyliari, Panagiota Potsaki, Panoraia Bousdouni, Chrysoula Kaloteraki, Martha Christofilea, Kalliopi Almpounioti, Andreani Moutsou, Chistodoulos K. Fasoulis, Leandros V. Polychronis, Vasileios K. Gkalpinos, Andreas G. Tzakos, Antonios E. Koutelidakis
Summary: There is a growing interest in fortifying dairy products with antioxidants and phenolics derived from plant byproducts and herbs. This study analyzed the antioxidant content, phenolic profile, and organoleptic characteristics of dairy products enhanced with aqueous extracts of plant byproducts and herbs. The results showed that the fortified dairy products had significant antioxidant and phenolic content, as well as bioavailability ranging from 4% to 68%. Mass spectrometry analysis revealed the presence of 162 phytochemicals, with most belonging to the polyphenol family. The identified compounds showed enhanced antioxidant capacity. Organoleptic evaluation showed acceptable overall acceptability. These findings suggest that the studied plants and herbal extracts can be used to fortify dairy products with potential health benefits.
Article
Chemistry, Multidisciplinary
Simona de Niederhausern, Moreno Bondi, Stefania Camellini, Carla Sabia, Patrizia Messi, Ramona Iseppi
Summary: The study showed that garlic and onion plant extracts have strong antimicrobial activity against Listeria monocytogenes. While the tests on sausages did not show significant differences, the plant extracts led to a noticeable initial reduction in viable L. monocytogenes count in cooked ham, extending the lag phase and reducing the growth rate of the pathogen. This suggests the potential for complete elimination of the pathogen in cooked ham with the use of plant extracts.
APPLIED SCIENCES-BASEL
(2021)
Article
Clinical Neurology
Shinwon Park, Ilhyang Kang, Richard A. E. Edden, Eun Namgung, Jinsol Kim, Jungyoon Kim
Article
Clinical Neurology
Jiyoung Ma, Myeongju Kim, Jungyoon Kim, Gahae Hong, Eun Namgung, Shinwon Park, Soo Mee Lim, In Kyoon Lyoo, Sujung Yoon
Article
Multidisciplinary Sciences
Jungyoon Kim, Sujung Yoon, Suji Lee, Haejin Hong, Eunji Ha, Yoonji Joo, Eun Hee Lee, In Kyoon Lyoo
NATURE COMMUNICATIONS
(2020)
Article
Endocrinology & Metabolism
Suji Lee, Yoon Ji Joo, Rye Young Kim, Jaeuk Hwang, Soo Mee Lim, Sujung Yoon, Jungyoon Kim
Article
Clinical Neurology
Jiyoung Ma, Gahae Hong, Eunji Ha, Haejin Hong, Jinsol Kim, Yoonji Joo, Sujung Yoon, In Kyoon Lyoo, Jungyoon Kim
Summary: Recent evidence suggests that hyperbaric oxygenation (HBO) may change neural activities in the human brain and improve symptoms of psychiatric disorders. This study found that low-pressure HBO increased regional cerebral blood flow (rCBF) of the limbic system in firefighters with mild traumatic brain injury (mTBI) and emotional distress, demonstrating a potential mechanism underlying HBO in the human brain.
NEUROLOGICAL SCIENCES
(2021)
Article
Clinical Neurology
Shinwon Park, Haejin Hong, Rye Young Kim, Jiyoung Ma, Suji Lee, Eunji Ha, Sujung Yoon, Jungyoon Kim
Summary: The study found that firefighters had lower cerebral blood flow in the right hemispheric regions compared to non-firefighter controls, and poor sleep quality was associated with decreased brain perfusion in the right orbitofrontal and insular cortices, as well as reduced working memory performance.
NATURE AND SCIENCE OF SLEEP
(2021)
Article
Family Studies
Myeongju Kim, Gahae Hong, Rye Young Kim, Yumi Song, Hyangwon Lee, Yoonji Joo, Jungyoon Kim, Sujung Yoon
Summary: The study found that childhood abuse has a negative impact on the severity of PTSD in adulthood, with resilience and coping strategies playing important mediating roles.
CHILD ABUSE & NEGLECT
(2021)
Review
Psychology, Biological
Jiyoung Ma, In Kyoon Lyoo, Perry F. Renshaw, Deborah A. Yurgelun-Todd
Summary: This review summarizes the effects of two major cannabinoids, delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), on brain metabolites. It focuses on human studies using magnetic resonance spectroscopy (MRS) and animal studies using more invasive methods. The evidence suggests that THC and CBD may have distinct effects on brain metabolite levels, and potential limitations and suggestions for future studies are discussed.
EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY
(2023)
Article
Clinical Neurology
Haejin Hong, Rye Young Kim, Yumi Song, Chaewon Suh, Hyangwon Lee, In Kyoon Lyoo, Sujung Yoon, Soo Mee Lim, Suji Lee
Summary: The effects of genetic variations in dopamine signaling on the heterogeneity of brain changes induced by repetitive transcranial magnetic stimulation (rTMS) are still unclear. This study found that high dopamine signaling individuals showed greater improvement in functional network connectivity and working memory performance after rTMS compared to low dopamine signaling individuals.
EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Suji Lee, Sujung Yoon, Eun Namgung, Tammy D. Kim, Haejin Hong, Eunji Ha, Rye Young Kim, Yumi Song, Hyangwon Lee, Chaewon Suh, In Kyoon Lyoo
Summary: This study aims to dissect the heterogeneity of posttraumatic conditions to identify clinically meaningful subtypes in recently traumatized individuals and evaluate their neurobiological correlates and long-term prognosis. A data-driven classification approach was implemented to identify four distinct and replicable subtypes for trauma-exposed individuals based on posttraumatic stress symptoms.
MOLECULAR PSYCHIATRY
(2023)
Article
Psychology, Multidisciplinary
Eun Namgung, Jungyoon Kim, Hyeonseok Jeong, Jiyoung Ma, Gahae Hong, Ilhyang Kang, Jinsol Kim, Yoonji Joo, Rye Young Kim, In Kyoon Lyoo
Summary: Computerized relaxation training was found to significantly improve stress-related symptoms in women with psychological distress by reducing prefrontal GABA levels and increasing relative CBF.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Neurosciences
Sujung Yoon, Jungyoon Kim, Gahae Hong, Tammy D. Kim, Haejin Hong, Eunji Ha, Jiyoung Ma, In Kyoon Lyoo
FRONTIERS IN SYSTEMS NEUROSCIENCE
(2020)
