Aspirin alone and combined with a statin suppresses eicosanoid formation in human colon tissue

Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice

(2017) Han-Byul Kim et al.   GASTROENTEROLOGY

Simvastatin Attenuates Endothelial Activation through 15-Epi-Lipoxin A4 Production in Murine Chronic Chagas Cardiomyopathy

(2016) Fabiola González-Herrera et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Statin Use Is Associated With Reduced Risk of Colorectal Cancer in Patients With Inflammatory Bowel Diseases

(2016) Ashwin N. Ananthakrishnan et al.   Clinical Gastroenterology and Hepatology

Statin use and the risk of colorectal adenoma: A meta-analysis

(2016) Yoon Suk Jung et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Celecoxib for the Prevention of Colorectal Adenomas: Results of a Suspended Randomized Controlled Trial

(2016) Patricia A. Thompson et al.   JNCI-Journal of the National Cancer Institute

Celecoxib for the Prevention of Colorectal Adenomas: Results of a Suspended Randomized Controlled Trial

(2016) Patricia A. Thompson et al.   JNCI-Journal of the National Cancer Institute

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity

(2015) Santiago Zelenay et al.   CELL

Statin Use Is Associated With Improved Prognosis of Colorectal Cancer in Taiwan

(2015) Yu-Yun Shao et al.   Clinical Colorectal Cancer

The efficacy and safety of non-steroidal anti-inflammatory drugs in preventing the recurrence of colorectal adenoma: a meta-analysis and systematic review of randomized trials

(2015) Y. Wang et al.   Colorectal Disease

Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections

(2015) Jesmond Dalli et al.   NATURE MEDICINE

Dual inhibition of COX-2/5-LOX blocks colon cancer proliferation, migration and invasion in vitro

(2015) XIAO-HANG CHE et al.   ONCOLOGY REPORTS

Protective effects of rosuvastatin in a rat model of lung contusion: Stimulation of the cyclooxygenase 2–prostaglandin E-2 pathway

(2015) Oleg Dolkart et al.   SURGERY

Advances in Our Understanding of Oxylipins Derived from Dietary PUFAs

(2015) Melissa Gabbs et al.   Advances in Nutrition

Statins Enhance Rotator Cuff Healing by Stimulating the COX2/PGE2/EP4 Pathway

(2014) Oleg Dolkart et al.   AMERICAN JOURNAL OF SPORTS MEDICINE

Comparison of sample preparation methods for the quantitative analysis of eicosanoids and other oxylipins in plasma by means of LC-MS/MS

(2014) Annika I. Ostermann et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Mast Cell-Derived Prostaglandin D2 Inhibits Colitis and Colitis-Associated Colon Cancer in Mice

(2014) K. Iwanaga et al.   CANCER RESEARCH

Aspirin use after diagnosis but not prediagnosis improves established colorectal cancer survival: a meta-analysis

(2014) Peiwei Li et al.   GUT

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Statin Use After Colorectal Cancer Diagnosis and Survival: A Population-Based Cohort Study

(2014) Chris R. Cardwell et al.   JOURNAL OF CLINICAL ONCOLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

An Inflammatory Mediator, Prostaglandin E2, in Colorectal Cancer

(2013) Dingzhi Wang et al.   CANCER JOURNAL

Statin Therapy Is Associated With Improved Pathologic Response to Neoadjuvant Chemoradiation in Rectal Cancer

(2013) Adam G. Mace et al.   DISEASES OF THE COLON & RECTUM

Colonoscopic Polypectomy and Long-Term Prevention of Colorectal-Cancer Deaths

(2012) Ann G. Zauber et al.   NEW ENGLAND JOURNAL OF MEDICINE

Omega-3 fatty acids and their lipid mediators: Towards an understanding of resolvin and protectin formation

(2012) Karsten H. Weylandt et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Combination of Atorvastatin with Sulindac or Naproxen Profoundly Inhibits Colonic Adenocarcinomas by Suppressing the p65/ -Catenin/Cyclin D1 Signaling Pathway in Rats

(2011) N. Suh et al.   Cancer Prevention Research

Inhibition of Intestinal Polyp Formation by Pitavastatin, a HMG-CoA Reductase Inhibitor

(2011) N. Teraoka et al.   Cancer Prevention Research

Prevention by daily soluble aspirin of colorectal adenoma recurrence: 4-year results of the APACC randomised trial

(2011) Robert Benamouzig et al.   GUT

Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

(2011) John Burn et al.   LANCET

Acetylsalicylic acid-triggered 15-HETE generation by peripheral leukocytes for identifying ASA sensitivity

(2011) Peter Korosec et al.   RESPIRATORY MEDICINE

Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials

(2010) Peter M Rothwell et al.   LANCET

Asymmetric Acetylation of the Cyclooxygenase-2 Homodimer by Aspirin and Its Effects on the Oxygenation of Arachidonic, Eicosapentaenoic, and Docosahexaenoic Acids

(2010) N. P. Sharma et al.   MOLECULAR PHARMACOLOGY

Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4

(2010) A Planagumà et al.   Mucosal Immunology

The Long-Term Use of Statins Is Associated with a Decreased Incidence of Adenomatous Colon Polyps

(2009) Ali A. Siddiqui et al.   DIGESTION

Gastroprotective effect of simvastatin against indomethacin-induced gastric ulcer in rats: Role of nitric oxide and prostaglandins

(2009) Gehan H. Heeba et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells

(2008) Hang Xiao et al.   INTERNATIONAL JOURNAL OF CANCER