Hematopoietic cell-derived RELMα regulates hookworm immunity through effects on macrophages

A novel blood-feeding detoxification pathway in Nippostrongylus brasiliensis L3 reveals a potential checkpoint for arresting hookworm development

(2018) Tiffany Bouchery et al.   PLoS Pathogens

Recent Advances in Type-2-Cell-Mediated Immunity: Insights from Helminth Infection

(2017) Nicola L. Harris et al.   IMMUNITY

Mouse eosinophil associated ribonucleases: Mechanism of cytotoxic, antibacterial and antiparasitic activities

(2017) Ayush Attery et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Interleukin-4 receptor alpha is still required after Th2 polarization for the maintenance and the recall of protective immunity to Nematode infection

(2017) Justin Komguep Nono et al.   PLoS Neglected Tropical Diseases

TM7SF3, a novel p53-regulated homeostatic factor, attenuates cellular stress and the subsequent induction of the unfolded protein response

(2016) Roi Isaac et al.   CELL DEATH AND DIFFERENTIATION

Immune polarization by hookworms: taking cues from T helper type 2, type 2 innate lymphoid cells and alternatively activated macrophages

(2016) Meera G. Nair et al.   IMMUNOLOGY

Comparison of RELMα and RELMβ Single- and Double-Gene-Deficient Mice Reveals that RELMα Expression Dictates Inflammation and Worm Expulsion in Hookworm Infection

(2016) Gang Chen et al.   INFECTION AND IMMUNITY

A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice

(2016) Riccardo Sibilano et al.   Nature Communications

Immunity to Helminths: Resistance, Regulation, and Susceptibility to Gastrointestinal Nematodes

(2015) Richard K. Grencis   Annual Review of Immunology

Interleukin-4 Receptor α Signaling in Myeloid Cells Controls Collagen Fibril Assembly in Skin Repair

(2015) Johanna A. Knipper et al.   IMMUNITY

Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis

(2015) L A Borthwick et al.   Mucosal Immunology

RGS1 regulates myeloid cell accumulation in atherosclerosis and aortic aneurysm rupture through altered chemokine signalling

(2015) Jyoti Patel et al.   Nature Communications

PDGFRα plays a crucial role in connective tissue remodeling

(2015) Shinjiro Horikawa et al.   Scientific Reports

Metalloproteinases and Wound Healing

(2015) Matthew P. Caley et al.   Advances in Wound Care

Hypoxia-induced mitogenic factor (FIZZ1/RELMα) induces endothelial cell apoptosis and subsequent interleukin-4-dependent pulmonary hypertension

(2014) Kazuyo Yamaji-Kegan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Neutrophils prime a long-lived effector macrophage phenotype that mediates accelerated helminth expulsion

(2014) Fei Chen et al.   NATURE IMMUNOLOGY

The In Vivo Fibrotic Role of FIZZ1 in Pulmonary Fibrosis

(2014) Tianju Liu et al.   PLoS One

Retnla Overexpression Attenuates Allergic Inflammation of the Airway

(2014) Mi-Ran Lee et al.   PLoS One

Human and Mouse Macrophages Collaborate with Neutrophils To Kill Larval Strongyloides stercoralis

(2013) Sandra Bonne-Année et al.   INFECTION AND IMMUNITY

FGF18 as a prognostic and therapeutic biomarker in ovarian cancer

(2013) Wei Wei et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage phenotypes during tissue repair

(2013) Margaret L. Novak et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Lung-resident CD4+ T cells are sufficient for IL-4Rα-dependent recall immunity to Nippostrongylus brasiliensis infection

(2013) S G Thawer et al.   Mucosal Immunology

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

(2013) Jan-Wilhelm Kornfeld et al.   NATURE

IL-4Rα-Associated Antigen Processing by B Cells Promotes Immunity in Nippostrongylus brasiliensis Infection

(2013) William G. C. Horsnell et al.   PLoS Pathogens

Regulation of Innate Responses during Pre-patent Schistosome Infection Provides an Immune Environment Permissive for Parasite Development

(2013) Diana K. Riner et al.   PLoS Pathogens

Antibodies Trap Tissue Migrating Helminth Larvae and Prevent Tissue Damage by Driving IL-4Rα-Independent Alternative Differentiation of Macrophages

(2013) Julia Esser-von Bieren et al.   PLoS Pathogens

Resistin-Like Molecule–α Regulates IL-13–Induced Chemokine Production but Not Allergen-Induced Airway Responses

(2012) Ariel Munitz et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The FGF8-related signals Pyramus and Thisbe promote pathfinding, substrate adhesion, and survival of migrating longitudinal gut muscle founder cells

(2012) Ingolf Reim et al.   DEVELOPMENTAL BIOLOGY

Trefoil factor 2 rapidly induces interleukin 33 to promote type 2 immunity during allergic asthma and hookworm infection

(2012) Marsha Wills-Karp et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mice Deficient in Ficolin, a Lectin Complement Pathway Recognition Molecule, Are Susceptible to Streptococcus pneumoniae Infection

(2012) Y. Endo et al.   JOURNAL OF IMMUNOLOGY

An essential role for TH2-type responses in limiting acute tissue damage during experimental helminth infection

(2012) Fei Chen et al.   NATURE MEDICINE

Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response

(2012) N. J. Szerlip et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alternatively activated dendritic cells regulate CD4+ T-cell polarization in vitro and in vivo

(2012) P. C. Cook et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Lung Is an Important Site for Priming CD4 T-Cell-Mediated Protective Immunity against Gastrointestinal Helminth Parasites

(2010) M. Harvie et al.   INFECTION AND IMMUNITY

Blood Fluke Exploitation of Non-Cognate CD4+ T Cell Help to Facilitate Parasite Development

(2010) Erika W. Lamb et al.   PLoS Pathogens

Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection

(2009) De'Broski R. Herbert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Alternatively activated macrophage-derived RELM-α is a negative regulator of type 2 inflammation in the lung

(2009) Meera G. Nair et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Resistin-Like Molecule   Decreases Glucose Tolerance during Intestinal Inflammation

(2009) A. Munitz et al.   JOURNAL OF IMMUNOLOGY

Semaphorin 5A promotes angiogenesis by increasing endothelial cell proliferation, migration, and decreasing apoptosis

(2009) Anguraj Sadanandam et al.   MICROVASCULAR RESEARCH

Retnla (Relmα/Fizz1) Suppresses Helminth-Induced Th2-Type Immunity

(2009) John T. Pesce et al.   PLoS Pathogens

Role of Junctional Adhesion Molecule-Like Protein in Mediating Monocyte Transendothelial Migration

(2008) Ya-Lan Guo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Th2 Cytokine-Induced Alterations in Intestinal Smooth Muscle Function Depend on Alternatively Activated Macrophages

(2008) Aiping Zhao et al.   GASTROENTEROLOGY

Resistin-like molecule α enhances myeloid cell activation and promotes colitis

(2008) Ariel Munitz et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

FIZZ1 Plays a Crucial Role in Early Stage Airway Remodeling of OVA-Induced Asthma

(2008) Liang Dong et al.   JOURNAL OF ASTHMA

Dynamics of lung macrophage activation in response to helminth infection

(2008) Mark C. Siracusa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Moving targets: cell migration inhibitors as new anti-inflammatory therapies

(2008) Charles R Mackay   NATURE IMMUNOLOGY