MAIT cell-mediated cytotoxicity: Roles in host defense and therapeutic potentials in infectious diseases and cancer
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Title
MAIT cell-mediated cytotoxicity: Roles in host defense and therapeutic potentials in infectious diseases and cancer
Authors
Keywords
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Journal
JOURNAL OF LEUKOCYTE BIOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2018-04-18
DOI
10.1002/jlb.4ri0118-023r
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Note: Only part of the references are listed.- Mucosa-associated invariant T cells in malignancies: a faithful friend or formidable foe?
- (2018) S. M. Mansour Haeryfar et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- IL-12 and IL-7 synergize to control mucosal-associated invariant T-cell cytotoxic responses to bacterial infection
- (2018) Joshua C. Wallington et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Intra-Hepatic Depletion of Mucosal-Associated Invariant T Cells in Hepatitis C Virus-Induced Liver Inflammation
- (2017) Fabian J. Bolte et al. GASTROENTEROLOGY
- Decrease of CD69 levels on TCR Vα7.2+CD4+ innate-like lymphocytes is associated with impaired cytotoxic functions in chronic hepatitis B virus-infected patients
- (2017) Yean K Yong et al. Innate Immunity
- Activation of Human Mucosal-Associated Invariant T Cells Induces CD40L-Dependent Maturation of Monocyte-Derived and Primary Dendritic Cells
- (2017) Mariolina Salio et al. JOURNAL OF IMMUNOLOGY
- Mucosal-Associated Invariant T Cells Are More Activated in Chronic Hepatitis B, but Not Depleted in Blood: Reversal by Antiviral Therapy
- (2017) Lauke L Boeijen et al. JOURNAL OF INFECTIOUS DISEASES
- Multiple layers of heterogeneity and subset diversity in human MAIT cell responses to distinct microorganisms and to innate cytokines
- (2017) Joana Dias et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation
- (2017) Martin Solders et al. Scientific Reports
- MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression
- (2017) Christopher R. Shaler et al. PLOS BIOLOGY
- Shared and Distinct Phenotypes and Functions of Human CD161++ Vα7.2+ T Cell Subsets
- (2017) Ayako Kurioka et al. Frontiers in Immunology
- Steroid-induced Deficiency of Mucosal-associated Invariant T Cells in the Chronic Obstructive Pulmonary Disease Lung. Implications for NontypeableHaemophilus influenzaeInfection
- (2016) Timothy S. C. Hinks et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Nonreversible MAIT cell-dysfunction in chronic hepatitis C virus infection despite successful interferon-free therapy
- (2016) Julia Hengst et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The role of mucosal-associated invariant T cells in infectious diseases
- (2016) Emily B. Wong et al. IMMUNOLOGY
- Antigen processing and immune regulation in the response to tumours
- (2016) Emma Reeves et al. IMMUNOLOGY
- Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1
- (2016) Hannah C. Jeffery et al. JOURNAL OF HEPATOLOGY
- Mucosal-associated invariant T cells from patients with tuberculosis exhibit impaired immune response
- (2016) Jing Jiang et al. JOURNAL OF INFECTION
- Human MAIT-cell responses to Escherichia coli : activation, cytokine production, proliferation, and cytotoxicity
- (2016) Joana Dias et al. JOURNAL OF LEUKOCYTE BIOLOGY
- MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation
- (2016) A Gibbs et al. Mucosal Immunology
- Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18–dependent activation
- (2016) Liyen Loh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Analysis of the Phenotype and Function of the Subpopulations of Mucosal-Associated Invariant T Cells
- (2016) J. Brozova et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Human TRAV1-2-negative MR1-restricted T cells detect S. pyogenes and alternatives to MAIT riboflavin-based antigens
- (2016) Erin W. Meermeier et al. Nature Communications
- MAIT cells are activated during human viral infections
- (2016) Bonnie van Wilgenburg et al. Nature Communications
- Clinical relevance of circulating mucosal-associated invariant T cell levels and their anti-cancer activity in patients with mucosal-associated cancer
- (2016) Eun Jeong Won et al. Oncotarget
- Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling
- (2016) Jing Jiang et al. Scientific Reports
- Circulating and tumor-infiltrating mucosal associated invariant T (MAIT) cells in colorectal cancer patients
- (2016) Limian Ling et al. Scientific Reports
- Increased tumor infiltration by mucosal-associated invariant T cells correlates with poor survival in colorectal cancer patients
- (2015) Luciane Zabijak et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Recovery of mucosal-associated invariant T cells after myeloablative chemotherapy and autologous peripheral blood stem cell transplantation
- (2015) Jan Novak et al. CLINICAL AND EXPERIMENTAL MEDICINE
- IL-15 dependent induction of IL-18 secretion as a feedback mechanism controlling human MAIT-cell effector functions
- (2015) Arne Sattler et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- MR1-restricted mucosal associated invariant T (MAIT) cells in the immune response toMycobacterium tuberculosis
- (2015) Marielle C. Gold et al. IMMUNOLOGICAL REVIEWS
- High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells
- (2015) Prabhat K. Sharma et al. IMMUNOLOGY
- Mucosal-associated invariant T cell–rich congenic mouse strain allows functional evaluation
- (2015) Yue Cui et al. JOURNAL OF CLINICAL INVESTIGATION
- Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients
- (2015) Isabelle Magalhaes et al. JOURNAL OF CLINICAL INVESTIGATION
- Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers
- (2015) Azad Rahimpour et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Human Mucosa-Associated Invariant T Cells Accumulate in Colon Adenocarcinomas but Produce Reduced Amounts of IFN-γ
- (2015) Patrik Sundström et al. JOURNAL OF IMMUNOLOGY
- Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites
- (2015) Isaac G. Sakala et al. JOURNAL OF IMMUNOLOGY
- Altered Distribution and Increased IL-17 Production by Mucosal-Associated Invariant T Cells in Adult and Childhood Obesity
- (2015) Eirin Carolan et al. JOURNAL OF IMMUNOLOGY
- In Vitro and In Vivo Analysis of the Gram-Negative Bacteria–Derived Riboflavin Precursor Derivatives Activating Mouse MAIT Cells
- (2015) Claire Soudais et al. JOURNAL OF IMMUNOLOGY
- Mucosal-associated invariant T cells are numerically and functionally deficient in patients with mycobacterial infection and reflect disease activity
- (2015) Yong-Soo Kwon et al. TUBERCULOSIS
- Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection
- (2015) Edwin Leeansyah et al. PLoS Pathogens
- Mucosal-Associated Invariant T Cells in the Human Gastric Mucosa and Blood: Role in Helicobacter pylori Infection
- (2015) Jayaum S. Booth et al. Frontiers in Immunology
- Editorial: CD1- and MR1-Restricted T Cells in Antimicrobial Immunity
- (2015) S.M. Mansour Haeryfar et al. Frontiers in Immunology
- Role of Innate T Cells in Anti-Bacterial Immunity
- (2015) Yifang Gao et al. Frontiers in Immunology
- MR1-Restricted Mucosal-Associated Invariant T Cells and Their Activation during Infectious Diseases
- (2015) Lauren J. Howson et al. Frontiers in Immunology
- The Role of Mucosal Associated Invariant T Cells in Antimicrobial Immunity
- (2015) Ruth J. Napier et al. Frontiers in Immunology
- Innate mucosal-associated invariant T (MAIT) cells are activated in inflammatory bowel diseases
- (2014) N.-E. Serriari et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- CD8+MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis
- (2014) Anne Willing et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets
- (2014) A Kurioka et al. Mucosal Immunology
- T-cell activation by transitory neo-antigens derived from distinct microbial pathways
- (2014) Alexandra J. Corbett et al. NATURE
- Low Levels of Peripheral CD161++CD8+ Mucosal Associated Invariant T (MAIT) Cells Are Found in HIV and HIV/TB Co-Infection
- (2014) Emily B. Wong et al. PLoS One
- CD161+ MAIT Cells Are Severely Reduced in Peripheral Blood and Lymph Nodes of HIV-Infected Individuals Independently of Disease Progression
- (2014) Johanna Maria Eberhard et al. PLoS One
- Acquisition of innate-like microbial reactivity in mucosal tissues during human fetal MAIT-cell development
- (2014) Edwin Leeansyah et al. Nature Communications
- CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages
- (2014) Joannah R. Fergusson et al. Cell Reports
- Mucosal-Associated Invariant T-Cells: New Players in Anti-Bacterial Immunity
- (2014) James E. Ussher et al. Frontiers in Immunology
- Genetically coupled receptor-ligand pair NKp80-AICL enables autonomous control of human NK cell responses
- (2013) S. N. Klimosch et al. BLOOD
- Expansion of Functional Human Mucosal-Associated Invariant T Cells via Reprogramming to Pluripotency and Redifferentiation
- (2013) Hiroshi Wakao et al. Cell Stem Cell
- MAIT cells, surveyors of a new class of antigen: development and functions
- (2013) Lionel Le Bourhis et al. CURRENT OPINION IN IMMUNOLOGY
- CD161++CD8+T cells, including the MAIT cell subset, are specifically activated by IL-12+IL-18 in a TCR-independent manner
- (2013) James E. Ussher et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Specific MAIT cell behaviour among innate-like T lymphocytes in critically ill patients with severe infections
- (2013) David Grimaldi et al. INTENSIVE CARE MEDICINE
- Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells
- (2013) Rangsima Reantragoon et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Double Positive Thymocytes Select Mucosal-Associated Invariant T Cells
- (2013) N. Seach et al. JOURNAL OF IMMUNOLOGY
- IL-7 Licenses Activation of Human Liver Intrasinusoidal Mucosal-Associated Invariant T Cells
- (2013) X.-Z. Tang et al. JOURNAL OF IMMUNOLOGY
- Inhibition of IL-17A in Tumor Microenvironment Augments Cytotoxicity of Tumor-Infiltrating Lymphocytes in Tumor-Bearing Mice
- (2013) Keiji Hayata et al. PLoS One
- MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection
- (2013) A. Meierovics et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MAIT Cells Detect and Efficiently Lyse Bacterially-Infected Epithelial Cells
- (2013) Lionel Le Bourhis et al. PLoS Pathogens
- Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection
- (2012) E. Leeansyah et al. BLOOD
- Early and nonreversible decrease of CD161++/MAIT cells in HIV infection
- (2012) C. Cosgrove et al. BLOOD
- Analysis of stem-cell-like properties of human CD161++IL-18R + memory CD8+ T cells
- (2012) S. H. C. Havenith et al. INTERNATIONAL IMMUNOLOGY
- Human MAIT and CD8 cells develop from a pool of type-17 precommitted CD8+ T cells
- (2011) L. J. Walker et al. BLOOD
- NKG2D performs two functions in invariant NKT cells: Direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d
- (2011) Carlotta Kuylenstierna et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells
- (2010) M. Dusseaux et al. BLOOD
- Activating and inhibitory receptors of natural killer cells
- (2010) Hollie J Pegram et al. IMMUNOLOGY AND CELL BIOLOGY
- Tumor cells of non-hematopoietic and hematopoietic origins express activation-induced C-type lectin, the ligand for killer cell lectin-like receptor F1
- (2010) A. Akatsuka et al. INTERNATIONAL IMMUNOLOGY
- IL-17 Promotes Tumor Development through the Induction of Tumor Promoting Microenvironments at Tumor Sites and Myeloid-Derived Suppressor Cells
- (2010) Donggou He et al. JOURNAL OF IMMUNOLOGY
- The non-conventional MHC class I MR1 molecule controls infection by Klebsiella pneumoniae in mice
- (2010) Philippe Georgel et al. MOLECULAR IMMUNOLOGY
- Antimicrobial activity of mucosal-associated invariant T cells
- (2010) Lionel Le Bourhis et al. NATURE IMMUNOLOGY
- Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties
- (2010) E. Billerbeck et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NKT cell costimulation: experimental progress and therapeutic promise
- (2010) Marianne J. van den Heuvel et al. TRENDS IN MOLECULAR MEDICINE
- Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells
- (2010) Marielle C. Gold et al. PLOS BIOLOGY
- Functional role of human NK cell receptor 2B4 (CD244) isoforms
- (2009) Stephen O. Mathew et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution
- (2009) S. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stepwise Development of MAIT Cells in Mouse and Human
- (2009) Emmanuel Martin et al. PLOS BIOLOGY
- The Transcription Factor PLZF Directs the Effector Program of the NKT Cell Lineage
- (2008) Adam K. Savage et al. IMMUNITY
- Invariant V 7.2-J 33 TCR is expressed in human kidney and brain tumors indicating infiltration by mucosal-associated invariant T (MAIT) cells
- (2008) A. Peterfalvi et al. INTERNATIONAL IMMUNOLOGY
- Functions of natural killer cells
- (2008) Eric Vivier et al. NATURE IMMUNOLOGY
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