Transgelin-2 in immunity: Its implication in cell therapy

Transgelin-2 as a therapeutic target for asthmatic pulmonary resistance

(2018) Lei-Miao Yin et al.   Science Translational Medicine

Transgelin-2 is upregulated on activated B-cells and expressed in hyperplastic follicles in lupus erythematosus patients

(2017) Kaori Kiso et al.   PLoS One

Transgelin-2: A potential oncogenic factor

(2017) Ti Meng et al.   TUMOR BIOLOGY

An Essential Role for TAGLN2 in Phagocytosis of Lipopolysaccharide-activated Macrophages

(2017) Hye-Ran Kim et al.   Scientific Reports

Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation

(2017) Marco Fritzsche et al.   Science Advances

Cancer immunotherapy: the beginning of the end of cancer?

(2016) Sofia Farkona et al.   BMC Medicine

The tumor-suppressive function of miR-1 by targeting LASP1 and TAGLN2 in esophageal squamous cell carcinoma

(2016) Yan-Yan Du et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Functional significance of transgelin-2 in uterine cervical squamous cell carcinoma

(2016) Kazuyuki Yakabe et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH

Transgelin-2 in B-Cells Controls T-Cell Activation by Stabilizing T Cell - B Cell Conjugates

(2016) Bo-Ra Na et al.   PLoS One

Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological Synapse

(2016) William A. Comrie et al.   Frontiers in Immunology

TAGLN2-mediated actin stabilization at the immunological synapse: implication for cytotoxic T cell control of target cells

(2015) Bo-Ra Na et al.   BMB Reports

Phytocomponent 4-hydroxy-3-methoxycinnamaldehyde ablates T-cell activation by targeting protein kinase C-θ and its downstream pathways

(2015) Uroos Akber et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse

(2015) Bo-Ra Na et al.   JOURNAL OF CELL BIOLOGY

The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobility

(2015) William A. Comrie et al.   JOURNAL OF CELL BIOLOGY

Quantitative Phosphoproteomics Revealed Glucose-Stimulated Responses of Islet Associated with Insulin Secretion

(2015) Jiaming Li et al.   JOURNAL OF PROTEOME RESEARCH

Rab31 and APPL2 enhance FcγR-mediated phagocytosis through PI3K/Akt signaling in macrophages

(2015) Jeremy C. Yeo et al.   MOLECULAR BIOLOGY OF THE CELL

miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma

(2015) Nijiro Nohata et al.   Oncotarget

The role of the cytoskeleton at the immunological synapse

(2014) Alex T. Ritter et al.   IMMUNOLOGICAL REVIEWS

Constitutive ERK MAPK Activity Regulates Macrophage ATP Production and Mitochondrial Integrity

(2014) M. M. Monick et al.   JOURNAL OF IMMUNOLOGY

Cryo-EM reveals different coronin binding modes for ADP– and ADP–BeFx actin filaments

(2014) Peng Ge et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Targeting the actin cytoskeleton: selective antitumor action via trapping PKCɛ

(2014) F Foerster et al.   Cell Death & Disease

The pivotal position of the actin cytoskeleton in the initiation and regulation of B cell receptor activation

(2013) Wenxia Song et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Tumor-suppressivemicroRNA-143/145cluster targets hexokinase-2 in renal cell carcinoma

(2013) Hirofumi Yoshino et al.   CANCER SCIENCE

At the Bench: Preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy

(2013) Andrew M. Intlekofer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Phosphorylation of Smooth Muscle 22α Facilitates Angiotensin II–Induced ROS Production Via Activation of the PKCδ-P47 phox Axis Through Release of PKCδ and Actin Dynamics and Is Associated With Hypertrophy and Hyperplasia of Vascular Smooth Muscle Cells In Vitro and In Vivo

(2012) Pin Lv et al.   CIRCULATION RESEARCH

F-actin polymerization and retrograde flow drive sustained PLCγ1 signaling during T cell activation

(2012) Alexander Babich et al.   JOURNAL OF CELL BIOLOGY

EWI-2 Association with  -Actinin Regulates T Cell Immune Synapses and HIV Viral Infection

(2012) M. Gordon-Alonso et al.   JOURNAL OF IMMUNOLOGY

Integration of the movement of signaling microclusters with cellular motility in immunological synapses

(2012) Peter Beemiller et al.   NATURE IMMUNOLOGY

The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer

(2011) H Yoshino et al.   BRITISH JOURNAL OF CANCER

The functional significance of miR-1 and miR-133a in renal cell carcinoma

(2011) Kazumori Kawakami et al.   EUROPEAN JOURNAL OF CANCER

Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma

(2011) Yasumitsu Moriya et al.   JOURNAL OF HUMAN GENETICS

Plasma membrane proteomes of differentially matured dendritic cells identified by LC–MS/MS combined with iTRAQ labelling

(2011) Stéphanie Ferret-Bernard et al.   Journal of Proteomics

A novel interplay between oncogenic PFTK1 protein kinase and tumor suppressor TAGLN2 in the control of liver cancer cell motility

(2011) W K C Leung et al.   ONCOGENE

Early Events in B Cell Activation

(2010) Naomi E. Harwood et al.   Annual Review of Immunology

Proteomics of Smad4 regulated transforming growth factor-beta signalling in colon cancer cells

(2010) Naveid Ahmad Ali et al.   Molecular BioSystems

LFA-1 Affinity Regulation Is Necessary for the Activation and Proliferation of Naive T Cells

(2009) Yang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The actin cytoskeleton in cancer cell motility

(2008) Michael F. Olson et al.   CLINICAL & EXPERIMENTAL METASTASIS

microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart

(2008) N. Liu et al.   GENES & DEVELOPMENT

Transgelin: An actin-binding protein and tumour suppressor

(2008) Stephen J. Assinder et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Crystal structure of human transgelin

(2008) Ming Li et al.   JOURNAL OF STRUCTURAL BIOLOGY

Smooth muscle 22 alpha maintains the differentiated phenotype of vascular smooth muscle cells by inducing filamentous actin bundling

(2008) Mei Han et al.   LIFE SCIENCES