Modeling cognition and disease using human glial chimeric mice

Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitors Remyelinate the Brain and Rescue Behavioral Deficits following Radiation

(2015) Jinghua Piao et al.   Cell Stem Cell

Cell competition: how to eliminate your neighbours

(2014) M. Amoyel et al.   DEVELOPMENT

Neutral competition of stem cells is skewed by proliferative changes downstream of Hh and Hpo

(2014) M. Amoyel et al.   EMBO JOURNAL

An animal model for progressive multifocal leukoencephalopathy

(2014) Sheila A. Haley et al.   JOURNAL OF CLINICAL INVESTIGATION

Human glial chimeric mice reveal astrocytic dependence of JC virus infection

(2014) Yoichi Kondo et al.   JOURNAL OF CLINICAL INVESTIGATION

A Competitive Advantage by Neonatally Engrafted Human Glial Progenitors Yields Mice Whose Brains Are Chimeric for Human Glia

(2014) M. S. Windrem et al.   JOURNAL OF NEUROSCIENCE

Generating induced pluripotent stem cells for multiple sclerosis therapy

(2014) Valentina Fossati et al.   Regenerative Medicine

Efficient Generation of Myelinating Oligodendrocytes from Primary Progressive Multiple Sclerosis Patients by Induced Pluripotent Stem Cells

(2014) Panagiotis Douvaras et al.   Stem Cell Reports

Human iPSC-Derived Oligodendrocyte Progenitor Cells Can Myelinate and Rescue a Mouse Model of Congenital Hypomyelination

(2013) Su Wang et al.   Cell Stem Cell

Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice

(2013) Xiaoning Han et al.   Cell Stem Cell

Myc-driven endogenous cell competition in the early mammalian embryo

(2013) Cristina Clavería et al.   NATURE

Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain

(2013) Ethan G Hughes et al.   NATURE NEUROSCIENCE

Direct conversion of patient fibroblasts demonstrates non-cell autonomous toxicity of astrocytes to motor neurons in familial and sporadic ALS

(2013) K. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Yields of Oligodendrocyte Lineage Cells from Human Embryonic Stem Cells at Physiological Oxygen Tensions for Evaluation of Translational Biology

(2013) Sybil R.L. Stacpoole et al.   Stem Cell Reports

Local generation of glia is a major astrocyte source in postnatal cortex

(2012) Woo-Ping Ge et al.   NATURE

Glial Progenitor Cell-Based Treatment and Modeling of Neurological Disease

(2012) S. A. Goldman et al.   SCIENCE

Progenitor Cell–Based Treatment of the Pediatric Myelin Disorders

(2011) Steven A. Goldman   ARCHIVES OF NEUROLOGY

CD140a identifies a population of highly myelinogenic, migration-competent and efficiently engrafting human oligodendrocyte progenitor cells

(2011) Fraser J Sim et al.   NATURE BIOTECHNOLOGY

NG2 Glia Generate New Oligodendrocytes But Few Astrocytes in a Murine Experimental Autoimmune Encephalomyelitis Model of Demyelinating Disease

(2010) R. B. Tripathi et al.   JOURNAL OF NEUROSCIENCE

NG2+ CNS Glial Progenitors Remain Committed to the Oligodendrocyte Lineage in Postnatal Life and following Neurodegeneration

(2010) Shin H. Kang et al.   NEURON

Prospects of Cell Therapy for Disorders of Myelin

(2009) Tamir Ben-Hur et al.   Annals of the New York Academy of Sciences

Uniquely Hominid Features of Adult Human Astrocytes

(2009) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Differentiation of human oligodendrocytes from pluripotent stem cells

(2009) Bao-Yang Hu et al.   Nature Protocols

Fate determination of adult human glial progenitor cells

(2009) Fraser J. Sim et al.   Neuron Glia Biology

Neonatal Chimerization with Human Glial Progenitor Cells Can Both Remyelinate and Rescue the Otherwise Lethally Hypomyelinated Shiverer Mouse

(2008) Martha S. Windrem et al.   Cell Stem Cell

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

(2008) Koji Yamanaka et al.   NATURE NEUROSCIENCE

Remyelination in the CNS: from biology to therapy

(2008) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Polydendrocytes (NG2 cells): multifunctional cells with lineage plasticity

(2008) Akiko Nishiyama et al.   NATURE REVIEWS NEUROSCIENCE