Journal
JOURNAL OF INVESTIGATIVE DERMATOLOGY
Volume 138, Issue 2, Pages 248-251Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jid.2017.09.002
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Funding
- National Institutes of Health [4R00ES022640]
- WSU College of Pharmacy
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Acute exposure of skin to UV-B causes DNA damage and sunburn erythema in both mice and humans. Previous studies documented time-of-day-related differences in sunburn responses after UV-B exposure in mice. Because humans are diurnal and mice are nocturnal, the circadian rhythm in human skin was hypothesized to be in opposite phase to the rhythm in mice. A study by Nikkola et al. demonstrates that humans are more prone to sunburn erythema after evening exposure to solar UV-B radiation as compared with morning exposure.
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