Article
Entomology
Yuyu Lei, Ying Li, Xinfeng Yang, Xuwei Zhu, Xian Zhang, Jie Du, Shimei Liang, Shanshan Li, Jianping Duan
Summary: Antheraea pernyi is an important resource for silk, food, and biohealth products, but exogenous pathogens hinder its commercial application potential. Through comparative transcriptome analysis, a gut-specific molecular tool, LITAF gene, was identified in A. pernyi, showing potential for immune response and future research and breeding applications. Immune challenge assays with nucleopolyhedrovirus and bacteria further indicated the role of ApLITAF in immune response in A. pernyi.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2021)
Article
Entomology
Yu-Lan Piao, Chun-Yang Zhang, Yue Zhang, Kun Qian, Ying Zhou, Jun-Yan Liu, Young-Cheol Chang, Hoon Cho, Dubok Choi
Summary: In this study, the wound-healing effect of Antheraea pernyi epidermal growth factor (ApEGF) was evaluated through sequence analysis, cloning, and prokaryotic expression. The results showed that ApEGF promoted cell growth and healing, making it a potential therapy for wound healing.
Article
Biochemistry & Molecular Biology
Dong-Bin Chen, Run-Xi Xia, Qun Li, Yu-Ping Li, Hui-Ying Cao, Yan-Qun Liu
Summary: This study identified 281 detoxification genes in the commercial wild silkworm, and found that certain genes play a role in detoxification of insecticides at safe concentrations, highlighting the importance of detoxification gene repertoire in insect pesticide tolerance.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Xin Fu, Miaomiao Chen, Runxi Xia, Xinyu Li, Qun Li, Yuping Li, Huiying Cao, Yanqun Liu
Summary: In this study, the cuticular proteins (CPs) in the genome of Antheraea pernyi were identified and compared with those of Bombyx mori. It was found that A. pernyi expressed more RR-2 genes during the pupal stage compared to B. mori, but expressed less RR-2 genes in the prothoracic gland. This suggests that the difference in hardness between the pupal skin and prothoracic gland of the two species may be caused by the number of expressed RR-2 genes. Additionally, it was revealed that B. mori expressed a higher number of CP genes in the antennae and prothoracic gland of the fifth instar larva than in the larval epidermis. This study provides an overall framework for functional research on CP genes in Saturniidae.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agronomy
Qian-Qian Mi, Jin-Ping Zhang, Muhammad Yasir Ali, Yong-Zhi Zhong, Nicholas J. Mills, Dun-Song Li, Yu-Ming Lei, Feng Zhang
Summary: This study assessed the reproductive attributes and functional response of Anastatus japonicus on a factitious host. The results showed that the sex ratio of adult progeny was slightly male biased, and individual wasps were unable to effectively respond to increasing host density. Therefore, releasing larger numbers of wasps and considering mutual interference among them should be taken into account in practical biological control programs.
PEST MANAGEMENT SCIENCE
(2022)
Article
Polymer Science
Jia Li, Bo-Xiang Wang, De-Hong Cheng, Yan-Hua Lu
Summary: The Antheraea Pernyi silk gland protein has been synthesized by tussah silk glands and shows great potential as a biomaterial due to its excellent biocompatibility. In this study, drug-loaded bio-hydrogels based on Antheraea Pernyi silk gland protein were fabricated using an eco-friendly method. The results demonstrate the porous structure and high drug release capability of the bio-hydrogels, as well as their non-toxic and pro-proliferative effects on cultured cells.
Article
Engineering, Biomedical
Xue Zhang, Wenbi Wu, Yulan Huang, Xiong Yang, Maling Gou
Summary: The application of 3D bioprinting in the biomedical field is growing, but the lack of bioinks that have both biocompatibility and printability remains a challenge. Silk fibroin materials are promising for biomedical applications due to their good biocompatibility. In this study, an ASF-based bioink was developed for DLP 3D bioprinting. The ASF-MA hydrogel showed mechanical properties, biocompatibility, and improved cell adhesion. Furthermore, the ASF-MA hydrogels promoted cell adhesion, migration, and proliferation. The ASF-MA hydrogels have potential applications in the biomedical field.
INTERNATIONAL JOURNAL OF BIOPRINTING
(2023)
Article
Physiology
Jie Du, Ping Zhao, Jiazhen Wang, Sanyuan Ma, Lunguang Yao, Xuwei Zhu, Xinfeng Yang, Xian Zhang, Zhenbo Sun, Shimei Liang, Dongxu Xing, Jianping Duan
Summary: This study optimized the dosage of 20-hydroxyecdysone (20E) to efficiently terminate the pupal diapause of Antheraea pernyi. Transcriptome analysis and qRT-PCR confirmed the expression patterns of genes involved in the process. These findings contribute to our understanding of the mechanism of pupal-adult transition and provide new methods and resources for the rearing and biotechnological development of A. pernyi.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Agriculture, Multidisciplinary
Qin Li, Yunqin Shen, Xingyue Guo, Yixuan Xu, Yuheng Mao, Yinfan Wu, Fang He, Caixia Wang, Yanqiu Chen, Yan Yang
Summary: Betanin can dose-dependently alleviate allergic asthma and upregulate the cAMP-PKA-CREB pathway. This study provides a novel nutritional strategy for the treatment of allergic asthma.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Fisheries
Chen Chen, Liangli Yang, Muhammad Nadeem Abbas, Deng Zou, Jun Li, Xuexia Geng, Haijun Zhang, Yuxuan Sun
Summary: This study reveals the importance of autophagy in innate immunity and its relationship with LPS-induced immune response in A. pernyi. The findings suggest that Relish gene regulates the transcription of ATG5 to eliminate Gram-negative bacteria through anti-microbial autophagy.
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY
(2022)
Article
Food Science & Technology
Shengchao Wang, Yun Meng, Dun Wang
Summary: This study reveals the dynamic changes in nutritional components of Antherea pernyi pupa after infection with Samsoniella hepiali. The content of polysaccharides and cordycepin increased with time while the content of fats and chitin decreased. The findings provide fundamental data to understand the nutritional value of the insect-fungus complex as human food and animal feed.
Article
Engineering, Biomedical
Ya Ma, Lian Duan, Jianfeng Sun, Shuangquan Gou, Fengyuan Chen, Yuqi Liang, Fangyin Dai, Bo Xiao
Summary: This study developed engineered Antheraea pernyi silk fibroin nanoparticles loaded with an anti-inflammatory drug, resveratrol, to target colonic epithelial cells and macrophages for effective ulcerative colitis (UC) treatment. The nanoparticles showed lysosomal escape capacity, pH and reactive oxygen species responsiveness, and targeted delivery to the cytoplasm for on-demand drug release. Oral treatment with these nanoparticles relieved UC symptoms by restoring damaged colonic epithelial barriers, reducing inflammation, and rebalancing intestinal microbiota.
Article
Polymer Science
Jia Li, Bo-Xiang Wang, De-Hong Cheng, Yue Zhang, Qiang Yao, Xin-bin Ji, Jing Guo, Yan-Hua Lu
Summary: To enhance the versatility of sodium alginate-loaded bio-hydrogels, Antheraea pernyi silk gland protein/sodium alginate drug-loaded hydrogels were prepared using an eco-friendly multiple network cross-link technology. The chemical structure and drug release behavior of the hydrogels were evaluated using Fourier transform infrared spectroscopy and UV-Vis spectrophotometer. The drug-loaded hydrogels exhibited strong interaction and 80% cumulative release within 400 minutes, and showed good antibacterial property and biocompatibility.
Article
Biochemistry & Molecular Biology
Chao Liu, Hong Zhao, Zhi-Hong Ji, Xin-Yu Yu
Summary: The study found that hyperhomocysteinemia leads to neuronal damage and loss in the hippocampal CA3 region, and downregulates CREB phosphorylation, which in turn induces memory impairment in rats.
NEUROCHEMICAL RESEARCH
(2022)
Article
Entomology
Shu Jia, Juntao Zhang, Xisheng Li, Yingzi He, Tinghong Yu, Chong Zhao, Ce Song
Summary: This study investigated the bacterial community in the midgut and feces of Antheraea pernyi larvae with and without AVD using 16S rRNA gene sequencing. The findings suggest that AVD infection alters the intestinal microflora in A. pernyi larvae, potentially leading to secondary bacterial infections. This is the first report of the presence of Turicibacter in the intestinal tract of lepidopterans.
JOURNAL OF ECONOMIC ENTOMOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Nan Zheng, Yu-Xuan Sun, Liang-Li Yang, Liang Wu, Muhammad Nadeem Abbas, Chen Chen, Jin Gao, Xiao-Kun Li, Chao-Liang Liu, Li-Shang Dai
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2018)
Article
Zoology
Jiawei Zhang, Qingqing Li, Guoqing Wei, Lei Wang, Cen Qian, Yu Sun, Jiwu Tian, Baojian Zhu, Chaoliang Liu
JOURNAL OF INVERTEBRATE PATHOLOGY
(2019)
Article
Biotechnology & Applied Microbiology
Shanshan Liu, Huihui Li, Zhenfei Guo, Junchang Guan, Yu Sun, Kai Zhang
INDIAN JOURNAL OF MICROBIOLOGY
(2019)
Article
Multidisciplinary Sciences
Liangli Yang, Junjun Dai, Qiuping Gao, Guozhen Yuan, Jiang Liu, Yu Sun, Yuxuan Sun, Lei Wang, Cen Qian, Baojian Zhu, Chaoliang Liu, Guoqing Wei
Article
Genetics & Heredity
Yu Sun, Hua Huang, Xiaojuan Zhang, Jun Xia, Jian Geng, Kai Zhang
MITOCHONDRIAL DNA PART B-RESOURCES
(2020)
Article
Biochemistry & Molecular Biology
Qingqing Li, Jiawei Zhang, Yu Sun, Lei Wang, Cen Qian, Guoqing Wei, Baojian Zhu, Chaoliang Liu
PROTEIN AND PEPTIDE LETTERS
(2020)
Article
Microbiology
Shanshan Liu, Huihui Li, Kai Zhang, Zhenfei Guo, Qingwei Zheng, Fuyong Hu, Wei Zhang, Yu Sun, Jun-chang Guan
Summary: This study investigated the phenotypic and genetic characteristics of Streptococcus mutans isolates from site-specific dental plaque in China, revealing differences between ECC and caries-free groups in terms of biofilm formation, pH decrease, and gene expression levels. Additionally, most ECC children shared an identical sequence type, while diversity was observed in the distribution of sequence types among different subjects. The findings suggest potential for child-to-child transmission of S. mutans.
JOURNAL OF MEDICAL MICROBIOLOGY
(2021)
Article
Multidisciplinary Sciences
Yu Sun, Hua Huang, Yudong Liu, Shanshan Liu, Jun Xia, Kai Zhang, Jian Geng
Summary: This study analyzed the complete mitochondrial genome of Speiredonia retorta, a pest belonging to the Lepidoptera order. The findings revealed consistency in mitogenome composition with other lepidopterans, and confirmed the species as a member of the Erebidae family through Bayesian inference and maximum likelihood models.
SCIENTIFIC REPORTS
(2021)
Article
Microbiology
Yudong Liu, Shanshan Liu, Qinghui Zhi, Peilin Zhuang, Rongxiu Zhang, Zhenzhen Zhang, Kai Zhang, Yu Sun
Summary: Arginine can reduce Streptococcus mutans biofilm growth and acid production by inhibiting glycolysis, amino sugar and nucleotide sugar metabolism, and peptidoglycan synthesis, leading to reductions in biofilm biomass and EPS production.
JOURNAL OF ORAL MICROBIOLOGY
(2022)
Article
Microbiology
Shanshan Liu, Yu Sun, Yudong Liu, Fuyong Hu, Li Xu, Qingwei Zheng, Qinglong Wang, Guojin Zeng, Kai Zhang
Summary: In this study, key target gene clusters against S. gordonii in S. mutans were identified and validated using clinical isolates. The expression levels of some genes were found to be consistent with RNA-seq results. These findings provide new targets for investigating critical gene clusters involved in the interaction between S. mutans and S. gordonii.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Genetics & Heredity
Yu Sun, Xiaojuan Zhang, Shanshan Liu, Jun Xia, Jian Geng, Kai Zhang
MITOCHONDRIAL DNA PART B-RESOURCES
(2019)
Article
Biochemistry & Molecular Biology
Saima Kausar, Muhammad Nadeem Abbas, Cen Qian, Baojian Zhu, Jin Gao, Yu Sun, Lei Wang, Guoqing Wei, Chaoliang Liu
ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Chen Chen, Salah Eldein, Xiaosan Zhou, Yu Sun, Jin Gao, Yuxuan Sun, Chaoliang Liu, Lei Wang
ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY
(2018)