Oxygen in mitochondrial disease: can there be too much of a good thing?

Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit

(2016) Massimo Girardis et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Hypoxia as a therapy for mitochondrial disease

(2016) I. H. Jain et al.   SCIENCE

The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease

(2015) James B. Stewart et al.   NATURE REVIEWS GENETICS

Association Between Hyperoxia and Mortality After Stroke

(2013) Fred Rincon et al.   CRITICAL CARE MEDICINE

New treatments for mitochondrial disease—no time to drop our standards

(2013) Gerald Pfeffer et al.   Nature Reviews Neurology

A Common Pathway for a Rare Disease?

(2013) S. B. Vafai et al.   SCIENCE

Mitochondrial disorders as windows into an ancient organelle

(2012) Scott B. Vafai et al.   NATURE

Relationship Between Supranormal Oxygen Tension and Outcome After Resuscitation From Cardiac Arrest

(2011) J. Hope Kilgannon et al.   CIRCULATION

Normobaric Hyperoxia in Traumatic Brain Injury: Does Brain Metabolic State Influence the Response to Hyperoxic Challenge?

(2011) Anna Vilalta et al.   JOURNAL OF NEUROTRAUMA

Mitochondrial aging is accelerated by anti-retroviral therapy through the clonal expansion of mtDNA mutations

(2011) Brendan A I Payne et al.   NATURE GENETICS