Histone deacetylase 2 (HDAC2) attenuates lipopolysaccharide (LPS)-induced inflammation by regulating PAI-1 expression

HDAC2 Suppresses IL17A-Mediated Airway Remodeling in Human and Experimental Modeling of COPD

(2018) Tianwen Lai et al.   CHEST

Plasminogen activator inhibitor-1 regulates macrophage-dependent postoperative adhesion by enhancing EGF-HER1 signaling in mice

(2017) Kumpei Honjo et al.   FASEB JOURNAL

Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications

(2017) Dana M. Hardbower et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasminogen activator inhibitor-1 stimulates macrophage activation through Toll-like Receptor-4

(2016) Kamlesh K. Gupta et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Role of Plasminogen Activator Inhibitor Type-1 in Fibrosis

(2016) Panagiotis Flevaris et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Neutrophil and Alveolar Macrophage-Mediated Innate Immune Control of Legionella pneumophila Lung Infection via TNF and ROS

(2016) Pascal Ziltener et al.   PLoS Pathogens

Elevated circulating PAI-1 levels are related to lung function decline, systemic inflammation, and small airway obstruction in chronic obstructive pulmonary disease

(2016) Fuqiang Wen et al.   International Journal of Chronic Obstructive Pulmonary Disease

Why a second look might be worth it: immuno-modulatory therapies in the critically ill patient

(2016) Benedikt H. Siegler et al.   Journal of Thoracic Disease

Inhibition of plasminogen activator inhibitor-1 is a potential therapeutic strategy in ovarian cancer

(2015) Satsuki Mashiko et al.   CANCER BIOLOGY & THERAPY

Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease: study protocol for a randomised controlled trial

(2015) Graham Devereux et al.   Trials

A Small Molecule Inhibitor to Plasminogen Activator Inhibitor 1 Inhibits Macrophage Migration

(2013) Atsuhiko Ichimura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The plasminogen activation system: new targets in lung inflammation and remodeling

(2013) Michael Schuliga et al.   CURRENT OPINION IN PHARMACOLOGY

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

(2013) R. P. Dellinger et al.   INTENSIVE CARE MEDICINE

Severe Sepsis and Septic Shock

(2013) Derek C. Angus et al.   NEW ENGLAND JOURNAL OF MEDICINE

TNF-α modulates statin effects on secretion and expression of MCP-1, PAI-1 and adiponectin in 3T3-L1 differentiated adipocytes

(2012) Sylvia Madeira de Vergueiro Lobo et al.   CYTOKINE

Regulation of macrophage inflammatory protein-2 gene expression in response to 2,4-dinitrofluorobenzene in RAW 264.7 cells

(2011) Dong-Bum Kim et al.   BMB Reports

REVIEW: Plasminogen Activator Inhibitor-1 (PAI-1): A Key Factor Linking Fibrinolysis and Age-Related Subclinical and Clinical Conditions

(2010) Matteo Cesari et al.   Cardiovascular Therapeutics

The Surviving Sepsis Campaign: Results of an international guideline-based performance improvement program targeting severe sepsis*

(2010) Mitchell M. Levy et al.   CRITICAL CARE MEDICINE

A Novel Inhibitor of Plasminogen Activator Inhibitor-1 Provides Antithrombotic Benefits Devoid of Bleeding Effect in Nonhuman Primates

(2010) Yuko Izuhara et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Inhibition of histone deacetylase activity down-regulates urokinase plasminogen activator and matrix metalloproteinase-9 expression in gastric cancer

(2010) Kyung Hee Lee et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Histone deacetylase inhibitor KBH-A42 inhibits cytokine production in RAW 264.7 macrophage cells and in vivo endotoxemia model

(2009) Yongseok Choi et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Forced IFIT-2 expression represses LPS induced TNF-alpha expression at posttranscriptional levels

(2008) Susanne Berchtold et al.   BMC IMMUNOLOGY